Water-soluble single molecular probe for simultaneous detection of viscosity and hydrazine.
Spectrochim Acta A Mol Biomol Spectrosc
; 294: 122558, 2023 Jun 05.
Article
em En
| MEDLINE
| ID: mdl-36863083
ABSTRACT
Hydrazine (N2H4) can cause serious damage to human health, while intracellular viscosity is highly associated with many diseases and cellular dysfunctions. Herein, we report the synthesis of a dual-responsive organic molecule-based fluorescent probe with excellent water solubility being capable of detection of N2H4 and viscosity through dual-fluorescence channels in "turn on" manner for both. Besides sensitive detection of N2H4 in aqueous solution with detection limit of 0.135 µM, this probe could be used for vapor N2H4 detection in colorimetric and fluorescent manners. In addition, the probe demonstrated viscosity-dependent fluorescence enhancement behavior, and as high as 150-fold enhancement could be obtained at 95% glycerol aqueous solution. Cell imaging experiment revealed that the probe could be used for the discriminating of living and dead cells.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Água
/
Sondas Moleculares
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Spectrochim Acta A Mol Biomol Spectrosc
Assunto da revista:
BIOLOGIA MOLECULAR
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
China