Multiomics analysis revealed the mechanisms related to the enhancement of proliferation, metastasis and EGFR-TKI resistance in EGFR-mutant LUAD with ARID1A deficiency.

Sun, Dantong; Feng, Feiyue; Teng, Fei; Xie, Tongji; Wang, Jinsong; Xing, Puyuan; Qian, Haili; Li, Junling

Sun, Dantong; Feng, Feiyue; Teng, Fei; Xie, Tongji; Wang, Jinsong; Xing, Puyuan; Qian, Haili; Li, Junling.

Afiliação

Sun D; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Feng F; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Teng F; Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Xie T; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Wang J; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Xing P; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Qian H; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. xingpuyuan@cicams.ac.cn.
Li J; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. qianhaili001@163.com.

Cell Commun Signal ; 21(1): 48, 2023 03 03.

Article em En | MEDLINE | ID: mdl-36869329

Assuntos

Adenocarcinoma de Pulmão; Neoplasias Pulmonares; Humanos; Multiômica; Proliferação de Células; Receptores ErbB; Proteínas de Ligação a DNA; Fatores de Transcrição

Palavras-chave

ARID1A; Cell cycle; EGFR-TKI resistance; EGFR-mutant LUAD; Multiomics analysis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adenocarcinoma de Pulmão / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cell Commun Signal Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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