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Bioanalysis of an antibody drug conjugate (ADC) PYX-201 in human plasma using a hybrid immunoaffinity LC-MS/MS approach.
Yin, Feng; Adhikari, Diana; Sun, Minghao; Shane Woolf, M; Ma, Eric; Mylott, William; Shaheen, Elizabeth; Harriman, Shawn; Pinkas, Jan.
Afiliação
  • Yin F; Department of Nonclinical Research, Pyxis Oncology, Inc., 321 Harrison Avenue, Suite 1, Boston, MA 02118, USA.
  • Adhikari D; Department of Nonclinical Research, Pyxis Oncology, Inc., 321 Harrison Avenue, Suite 1, Boston, MA 02118, USA.
  • Sun M; Chromatographic Services - Research & Development, Biologics by LC-MS/MS, PPD Laboratory Services, 8700 Quioccasin Road, Henrico, VA 23229, USA.
  • Shane Woolf M; Chromatographic Services - Research & Development, Biologics by LC-MS/MS, PPD Laboratory Services, 8700 Quioccasin Road, Henrico, VA 23229, USA.
  • Ma E; Chromatographic Services - Research & Development, Biologics by LC-MS/MS, PPD Laboratory Services, 8700 Quioccasin Road, Henrico, VA 23229, USA.
  • Mylott W; Chromatographic Services - Research & Development, Biologics by LC-MS/MS, PPD Laboratory Services, 8700 Quioccasin Road, Henrico, VA 23229, USA.
  • Shaheen E; Department of Project Management, Pyxis Oncology, Inc., 321 Harrison Avenue, Suite 1, Boston, MA 02118, USA.
  • Harriman S; Department of Nonclinical Research, Pyxis Oncology, Inc., 321 Harrison Avenue, Suite 1, Boston, MA 02118, USA. Electronic address: sharriman@pyxisoncology.com.
  • Pinkas J; Department of Nonclinical Research, Pyxis Oncology, Inc., 321 Harrison Avenue, Suite 1, Boston, MA 02118, USA. Electronic address: jpinkas@pyxisoncology.com.
Article em En | MEDLINE | ID: mdl-37094503

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoconjugados Limite: Humans Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoconjugados Limite: Humans Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos