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Targeting stromal cell sialylation reverses T cell-mediated immunosuppression in the tumor microenvironment.
Egan, Hannah; Treacy, Oliver; Lynch, Kevin; Leonard, Niamh A; O'Malley, Grace; Reidy, Eileen; O'Neill, Aoise; Corry, Shania M; De Veirman, Kim; Vanderkerken, Karin; Egan, Laurence J; Ritter, Thomas; Hogan, Aisling M; Redmond, Keara; Peng, Li; Che, Jenny; Gatlin, Wayne; Jayaraman, Pushpa; Sheehan, Margaret; Canney, Aoife; Hynes, Sean O; Kerr, Emma M; Dunne, Philip D; O'Dwyer, Michael E; Ryan, Aideen E.
Afiliação
  • Egan H; Discipline of Pharmacology and Therapeutics, School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Ireland; Regenerative Medicine Institute (REMEDI), School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Irel
  • Treacy O; Discipline of Pharmacology and Therapeutics, School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Ireland; Regenerative Medicine Institute (REMEDI), School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Irel
  • Lynch K; Discipline of Pharmacology and Therapeutics, School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Ireland; Regenerative Medicine Institute (REMEDI), School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Irel
  • Leonard NA; Discipline of Pharmacology and Therapeutics, School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Ireland; Regenerative Medicine Institute (REMEDI), School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Irel
  • O'Malley G; Discipline of Pharmacology and Therapeutics, School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Ireland; Regenerative Medicine Institute (REMEDI), School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Irel
  • Reidy E; Discipline of Pharmacology and Therapeutics, School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Ireland; Regenerative Medicine Institute (REMEDI), School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Irel
  • O'Neill A; Discipline of Pharmacology and Therapeutics, School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Ireland; Regenerative Medicine Institute (REMEDI), School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Irel
  • Corry SM; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.
  • De Veirman K; Laboratory for Haematology and Immunology (HEIM), Department of Biomedical Sciences, Vrije Universiteit Brussel, Brussels, Belgium.
  • Vanderkerken K; Laboratory for Haematology and Immunology (HEIM), Department of Biomedical Sciences, Vrije Universiteit Brussel, Brussels, Belgium.
  • Egan LJ; Discipline of Pharmacology and Therapeutics, School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Ireland; Lambe Institute for Translational Research, School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Ir
  • Ritter T; Regenerative Medicine Institute (REMEDI), School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Ireland; CÚRAM, SFI Research Centre for Medical Devices, University of Galway, Galway, Ireland.
  • Hogan AM; Lambe Institute for Translational Research, School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Ireland; Department of Colorectal Surgery, Galway University Hospital, Galway, Ireland.
  • Redmond K; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.
  • Peng L; Palleon Pharmaceuticals, Waltham, MA 02451, USA.
  • Che J; Palleon Pharmaceuticals, Waltham, MA 02451, USA.
  • Gatlin W; Palleon Pharmaceuticals, Waltham, MA 02451, USA.
  • Jayaraman P; Palleon Pharmaceuticals, Waltham, MA 02451, USA.
  • Sheehan M; Division of Anatomical Pathology, Galway University Hospital, Galway, Ireland.
  • Canney A; Division of Anatomical Pathology, Galway University Hospital, Galway, Ireland.
  • Hynes SO; Division of Anatomical Pathology, Galway University Hospital, Galway, Ireland; Discipline of Pathology, School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Ireland.
  • Kerr EM; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.
  • Dunne PD; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK; Cancer Research UK Beatson Institute, Glasgow, UK.
  • O'Dwyer ME; Lambe Institute for Translational Research, School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Ireland; Blood Cancer Network of Ireland (BCNI), Galway, Ireland; Department of Hematology, Galway University Hospital, Galway, Ireland.
  • Ryan AE; Discipline of Pharmacology and Therapeutics, School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Ireland; Regenerative Medicine Institute (REMEDI), School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Irel
Cell Rep ; 42(5): 112475, 2023 05 30.
Article em En | MEDLINE | ID: mdl-37167967
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fibroblastos Associados a Câncer / Neoplasias Limite: Humans Idioma: En Revista: Cell Rep Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fibroblastos Associados a Câncer / Neoplasias Limite: Humans Idioma: En Revista: Cell Rep Ano de publicação: 2023 Tipo de documento: Article