A novel statistical method for decontaminating T-cell receptor sequencing data.

Li, Ruoxing; Altan, Mehmet; Reuben, Alexandre; Lin, Ruitao; Heymach, John V; Tran, Hai; Chen, Runzhe; Little, Latasha; Hubert, Shawna; Zhang, Jianjun; Li, Ziyi

Li, Ruoxing; Altan, Mehmet; Reuben, Alexandre; Lin, Ruitao; Heymach, John V; Tran, Hai; Chen, Runzhe; Little, Latasha; Hubert, Shawna; Zhang, Jianjun; Li, Ziyi.

Afiliação

Li R; Department of Biostatistics and Data Science, The University of Texas Health Science Center at Houston, 77030, Texas, Houston, USA.
Altan M; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, 77030, Texas, Houston, USA.
Reuben A; Department of Thoracic-Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, 77030, Texas, Houston, USA.
Lin R; Department of Thoracic-Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, 77030, Texas, Houston, USA.
Heymach JV; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, 77030, Texas, Houston, USA.
Tran H; Department of Thoracic-Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, 77030, Texas, Houston, USA.
Chen R; Department of Thoracic-Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, 77030, Texas, Houston, USA.
Little L; Department of Thoracic-Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, 77030, Texas, Houston, USA.
Hubert S; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, 77030, Texas, Houston, USA.
Zhang J; Department of Thoracic-Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, 77030, Texas, Houston, USA.
Li Z; Department of Thoracic-Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, 77030, Texas, Houston, USA.

Brief Bioinform ; 24(4)2023 07 20.

Article em En | MEDLINE | ID: mdl-37337757

Assuntos

Receptores de Antígenos de Linfócitos T; Linfócitos T; Humanos; Teorema de Bayes; Receptores de Antígenos de Linfócitos T/genética; Modelos Estatísticos; Sequenciamento de Nucleotídeos em Larga Escala/métodos

Palavras-chave

Bayesian model; Contamination detection; TCR sequencing

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores de Antígenos de Linfócitos T / Linfócitos T Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Brief Bioinform Assunto da revista: BIOLOGIA / INFORMATICA MEDICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google