NIK-mediated reactivation of SIX2 enhanced the CSC-like traits of hepatocellular carcinoma cells through suppressing ubiquitin-proteasome system.

Daren, Liu; Dan, Ye; Jinhong, Wu; Chao, Li

Daren, Liu; Dan, Ye; Jinhong, Wu; Chao, Li.

Afiliação

Daren L; Department of General Surgery, The Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
Dan Y; Department of General Surgery, The Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
Jinhong W; Department of General Surgery, The Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
Chao L; Department of General Surgery, The Second Affiliated Hospital of Zhejiang University, Hangzhou, China.

Environ Toxicol ; 39(2): 583-591, 2024 Feb.

Article em En | MEDLINE | ID: mdl-37461228

Assuntos

Carcinoma Hepatocelular; Neoplasias Hepáticas; Humanos; Carcinoma Hepatocelular/patologia; Linhagem Celular Tumoral; Proteínas de Homeodomínio/genética; Neoplasias Hepáticas/patologia; Proteínas do Tecido Nervoso/genética; Quinase Induzida por NF-kappaB; Complexo de Endopeptidases do Proteassoma; Ubiquitina

Palavras-chave

NIK; SIX2; cancer stem cell; protein stability; ubiquitination

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas Limite: Humans Idioma: En Revista: Environ Toxicol Assunto da revista: SAUDE AMBIENTAL / TOXICOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google