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Targeting GLI1 and GLI2 with small molecule inhibitors to suppress GLI-dependent transcription and tumor growth.
Maresca, Luisa; Crivaro, Enrica; Migliorini, Francesca; Anichini, Giulia; Giammona, Alessandro; Pepe, Sara; Poggialini, Federica; Vagaggini, Chiara; Giannini, Giuseppe; Sestini, Serena; Borgognoni, Lorenzo; Lapucci, Andrea; Dreassi, Elena; Taddei, Maurizio; Manetti, Fabrizio; Petricci, Elena; Stecca, Barbara.
Afiliação
  • Maresca L; Core Research Laboratory - Institute for Cancer Research and Prevention (ISPRO), Florence, Italy.
  • Crivaro E; Core Research Laboratory - Institute for Cancer Research and Prevention (ISPRO), Florence, Italy; Dept. of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.
  • Migliorini F; Dept. of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.
  • Anichini G; Core Research Laboratory - Institute for Cancer Research and Prevention (ISPRO), Florence, Italy.
  • Giammona A; Core Research Laboratory - Institute for Cancer Research and Prevention (ISPRO), Florence, Italy.
  • Pepe S; Core Research Laboratory - Institute for Cancer Research and Prevention (ISPRO), Florence, Italy.
  • Poggialini F; Dept. of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.
  • Vagaggini C; Dept. of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.
  • Giannini G; R&D, Alfasigma SpA, Roma, Italy.
  • Sestini S; Plastic and Reconstructive Surgery Unit Regional Melanoma Referral Center and Melanoma & Skin Cancer Unit, Santa Maria Annunziata Hospital, Florence, Italy.
  • Borgognoni L; Plastic and Reconstructive Surgery Unit Regional Melanoma Referral Center and Melanoma & Skin Cancer Unit, Santa Maria Annunziata Hospital, Florence, Italy.
  • Lapucci A; Department of Health Sciences, University of Florence, Florence, Italy.
  • Dreassi E; Dept. of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.
  • Taddei M; Dept. of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.
  • Manetti F; Dept. of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy. Electronic address: fabrizio.manetti@unisi.it.
  • Petricci E; Dept. of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy. Electronic address: elena.petricci@unisi.it.
  • Stecca B; Core Research Laboratory - Institute for Cancer Research and Prevention (ISPRO), Florence, Italy. Electronic address: b.stecca@ispro.toscana.it.
Pharmacol Res ; 195: 106858, 2023 09.
Article em En | MEDLINE | ID: mdl-37473878
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína GLI1 em Dedos de Zinco / Proteína Gli2 com Dedos de Zinco / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína GLI1 em Dedos de Zinco / Proteína Gli2 com Dedos de Zinco / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália