Antidepressant-like effects of tomatidine and tomatine, steroidal alkaloids from unripe tomatoes, via activation of mTORC1 in the medial prefrontal cortex in lipopolysaccharide-induced depression model mice.

Deyama, Satoshi; Sugie, Rinako; Tabata, Masaki; Kaneda, Katsuyuki

Deyama, Satoshi; Sugie, Rinako; Tabata, Masaki; Kaneda, Katsuyuki.

Afiliação

Deyama S; Laboratory of Molecular Pharmacology, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
Sugie R; Laboratory of Molecular Pharmacology, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
Tabata M; Laboratory of Molecular Pharmacology, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
Kaneda K; Laboratory of Molecular Pharmacology, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.

Nutr Neurosci ; : 1-14, 2023 Sep 13.

Article em En | MEDLINE | ID: mdl-37704369

Palavras-chave

Antidepressant; depression; mechanistic target of rapamycin complex 1; medial prefrontal cortex; steroidal alkaloid; tomatidine; tomatine; tomato

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Nutr Neurosci Assunto da revista: CIENCIAS DA NUTRICAO / NEUROLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão

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