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A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes.
Chan, Magnus; Sahakyan, Harutyun; Eldstrom, Jodene; Sastre, Daniel; Wang, Yundi; Dou, Ying; Pourrier, Marc; Vardanyan, Vitya; Fedida, David.
Afiliação
  • Chan M; Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada.
  • Sahakyan H; Laboratory of Computational Modeling of Biological Processes, Institute of Molecular Biology, Yerevan, Armenia.
  • Eldstrom J; Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada.
  • Sastre D; Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada.
  • Wang Y; Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada.
  • Dou Y; Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada.
  • Pourrier M; Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada.
  • Vardanyan V; Molecular Neuroscience Group, Institute of Molecular Biology, Yerevan, Armenia.
  • Fedida D; Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada.
Elife ; 122023 09 14.
Article em En | MEDLINE | ID: mdl-37707495
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Calmodulina / Canal de Potássio KCNQ1 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Elife Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Calmodulina / Canal de Potássio KCNQ1 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Elife Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá