Protective effect of soy isolate protein against streptozotocin induced gestational diabetes mellitus via TLR4/MyD88/NF-&#954;B signaling pathway.

Wang, Shuijing; Ma, Liangkun; Ji, Jing; Huo, Ruichao; Dong, Shan; Bai, Yunfeng; Hua, Linlin; Lei, Jiao; Tian, Sasa; Wang, Manning; Yu, Yan

Protective effect of soy isolate protein against streptozotocin induced gestational diabetes mellitus via TLR4/MyD88/NF-κB signaling pathway.

Wang, Shuijing; Ma, Liangkun; Ji, Jing; Huo, Ruichao; Dong, Shan; Bai, Yunfeng; Hua, Linlin; Lei, Jiao; Tian, Sasa; Wang, Manning; Yu, Yan.

Afiliação

Wang S; School of Public Health, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, China; Shaanxi SANZ Pharmaceutical Co., Ltd, Xi'an, Shaanxi 710086, China.
Ma L; Department of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, PUMC Hospital, CAMS and PUMC, Beijing100730, China.
Ji J; Northwest Women's and Children's Hospital, Xi'an, Shaanxi 710061, China.
Huo R; Pingyao Agriculture and Rural Bureau, Pingyao, Shanxi 031100, China.
Dong S; Nutritional Department, Maternal and Child Health Care Hospital of HaiDian District, Beijing 100000, China.
Bai Y; School of Public Health, Shaanxi University of Chinese Medicine, Xianyang 712046, China.
Hua L; Department of Advanced Medical Research, The Second Affiliated Hospital of Zhengzhou University, Jingba road, Jinshui district, Zhengzhou 450014, China.
Lei J; Shaanxi SANZ Pharmaceutical Co., Ltd, Xi'an, Shaanxi 710086, China.
Tian S; Shaanxi SANZ Pharmaceutical Co., Ltd, Xi'an, Shaanxi 710086, China.
Wang M; Shaanxi SANZ Pharmaceutical Co., Ltd, Xi'an, Shaanxi 710086, China.
Yu Y; School of Public Health, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, China. Electronic address: yanyuxjt@hotmail.com.

Biomed Pharmacother ; 168: 115688, 2023 Dec.

Article em En | MEDLINE | ID: mdl-37890205

Assuntos

Diabetes Gestacional; Animais; Feminino; Gravidez; Ratos; Antioxidantes/farmacologia; Antioxidantes/metabolismo; Glicemia/metabolismo; Peso Corporal; Citocinas/metabolismo; Diabetes Gestacional/prevenção & controle; Glucose/metabolismo; Insulina/metabolismo; Lipídeos/sangue; Fator 88 de Diferenciação Mieloide/genética; Fator 88 de Diferenciação Mieloide/metabolismo; NF-kappa B/metabolismo; Placenta/metabolismo; Ratos Sprague-Dawley; RNA Mensageiro/metabolismo; Transdução de Sinais; Estreptozocina/farmacologia; Receptor 4 Toll-Like/genética; Receptor 4 Toll-Like/metabolismo

Palavras-chave

Antioxidant; Inflammation; Insulin; MRNA expression; Soy isolate protein

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diabetes Gestacional Limite: Animals / Pregnancy Idioma: En Revista: Biomed Pharmacother Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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