Preceding Night Sleep Quality and Atrial Fibrillation Episodes in the I-STOP-AFIB Randomized Trial.
JACC Clin Electrophysiol
; 10(1): 56-64, 2024 Jan.
Article
em En
| MEDLINE
| ID: mdl-37921790
ABSTRACT
BACKGROUND:
Chronic sleep disruption is associated with incident atrial fibrillation (AF), but it is unclear whether poor sleep quality acutely triggers AF.OBJECTIVES:
The aim of this study was to characterize the relationship between a given night's sleep quality and the risk of a discrete AF episode.METHODS:
Patients with symptomatic paroxysmal AF in the I-STOP-AFIB (Individualized Studies of Triggers of Paroxysmal Atrial Fibrillation) trial reported sleep quality on a daily basis. Participants were also queried daily regarding AF episodes and were provided smartphone-based mobile electrocardiograms (ECGs) (KardiaMobile, AliveCor).RESULTS:
Using 15,755 days of data from 419 patients, worse sleep quality on any given night was associated with a 15% greater odds of a self-reported AF episode the next day (OR 1.15; 95% CI 1.10-1.20; P < 0.0001) after adjustment for the day of the week. No statistically significant associations between worsening sleep quality and mobile ECG-confirmed AF events were observed (OR 1.04; 95% CI 0.95-1.13; P = 0.43), although substantially fewer of these mobile ECG-confirmed events may have limited statistical power. Poor sleep was also associated with longer self-reported AF episodes, with each progressive category of worsening sleep associated with 16 (95% CI 12-21; P < 0.001) more minutes of AF the next day.CONCLUSIONS:
Poor sleep was associated with an immediately heightened risk for self-reported AF episodes, and a dose-response relationship existed such that progressively worse sleep was associated with longer episodes of AF the next day. These data suggest that sleep quality may be a potentially modifiable trigger relevant to the near-term risk of a discrete AF episode.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fibrilação Atrial
Limite:
Humans
Idioma:
En
Revista:
JACC Clin Electrophysiol
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Estados Unidos