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First-in-human study to evaluate the safety, tolerability, and population pharmacokinetic/pharmacodynamic target attainment analysis of FL058 alone and in combination with meropenem in healthy subjects.
Huang, Zhiwei; Yang, Xinyi; Jin, Yi; Yu, Jicheng; Cao, Guoying; Wang, Jingjing; Hu, Yingying; Dai, Jingyi; Wu, Jufang; Wei, Qiong; Tian, Yan; Yu, Shuyan; Zhu, Xu; Mao, Xiaomeng; Liu, Wei; Liang, Hong; Zheng, Shansong; Ju, Yunfei; Wang, Zenghua; Zhang, Jing; Wu, Xiaojie.
Afiliação
  • Huang Z; Phase I Clinical Research Center, Huashan Hospital, Fudan University , Shanghai, China.
  • Yang X; Institute of Antibiotics, Huashan Hospital, Fudan University , Shanghai, China.
  • Jin Y; Phase I Clinical Research Center, Huashan Hospital, Fudan University , Shanghai, China.
  • Yu J; Phase I Clinical Research Center, Huashan Hospital, Fudan University , Shanghai, China.
  • Cao G; Phase I Clinical Research Center, Huashan Hospital, Fudan University , Shanghai, China.
  • Wang J; Phase I Clinical Research Center, Huashan Hospital, Fudan University , Shanghai, China.
  • Hu Y; Research Ward of Huashan Hospital, Fudan University , Shanghai, China.
  • Dai J; Phase I Clinical Research Center, Huashan Hospital, Fudan University , Shanghai, China.
  • Wu J; Phase I Clinical Research Center, Huashan Hospital, Fudan University , Shanghai, China.
  • Wei Q; Phase I Clinical Research Center, Huashan Hospital, Fudan University , Shanghai, China.
  • Tian Y; Phase I Clinical Research Center, Huashan Hospital, Fudan University , Shanghai, China.
  • Yu S; Phase I Clinical Research Center, Huashan Hospital, Fudan University , Shanghai, China.
  • Zhu X; Phase I Clinical Research Center, Huashan Hospital, Fudan University , Shanghai, China.
  • Mao X; Phase I Clinical Research Center, Huashan Hospital, Fudan University , Shanghai, China.
  • Liu W; Phase I Clinical Research Center, Huashan Hospital, Fudan University , Shanghai, China.
  • Liang H; Phase I Clinical Research Center, Huashan Hospital, Fudan University , Shanghai, China.
  • Zheng S; Phase I Clinical Research Center, Huashan Hospital, Fudan University , Shanghai, China.
  • Ju Y; Phase I Clinical Research Center, Huashan Hospital, Fudan University , Shanghai, China.
  • Wang Z; Qilu Pharmaceutical Co. Ltd. , Jinan, China.
  • Zhang J; Qilu Pharmaceutical Co. Ltd. , Jinan, China.
  • Wu X; Qilu Pharmaceutical Co. Ltd. , Jinan, China.
Antimicrob Agents Chemother ; 68(1): e0133023, 2024 Jan 10.
Article em En | MEDLINE | ID: mdl-38054726
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de beta-Lactamases / Antibacterianos Limite: Adult / Humans Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de beta-Lactamases / Antibacterianos Limite: Adult / Humans Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China