Levomilnacipran Improves Lipopolysaccharide-Induced Dysregulation of Synaptic Plasticity and Depression-Like Behaviors via Activating BDNF/TrkB Mediated PI3K/Akt/mTOR Signaling Pathway.

Wu, Yuhan; Zhu, Zhanpeng; Lan, Tian; Li, Shuhan; Li, Ye; Wang, Changmin; Feng, Yabo; Mao, Xueqin; Yu, Shuyan

Wu, Yuhan; Zhu, Zhanpeng; Lan, Tian; Li, Shuhan; Li, Ye; Wang, Changmin; Feng, Yabo; Mao, Xueqin; Yu, Shuyan.

Afiliação

Wu Y; Department of Physiology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, 44 Wenhuaxilu Road, Jinan, Shandong Province, 250012, People's Republic of China.
Zhu Z; Department of Physiology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, 44 Wenhuaxilu Road, Jinan, Shandong Province, 250012, People's Republic of China.
Lan T; Department of Physiology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, 44 Wenhuaxilu Road, Jinan, Shandong Province, 250012, People's Republic of China.
Li S; Department of Physiology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, 44 Wenhuaxilu Road, Jinan, Shandong Province, 250012, People's Republic of China.
Li Y; Department of Physiology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, 44 Wenhuaxilu Road, Jinan, Shandong Province, 250012, People's Republic of China.
Wang C; Department of Physiology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, 44 Wenhuaxilu Road, Jinan, Shandong Province, 250012, People's Republic of China.
Feng Y; Department of Neurology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province, 250021, People's Republic of China.
Mao X; Department of Psychology, Qilu Hospital of Shandong University, 107 Wenhuaxilu Road, Jinan, Shandong Province, 250012, People's Republic of China. m_xqin@126.com.
Yu S; Department of Physiology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, 44 Wenhuaxilu Road, Jinan, Shandong Province, 250012, People's Republic of China. shuyanyu@sdu.edu.cn.

Mol Neurobiol ; 2023 Dec 07.

Article em En | MEDLINE | ID: mdl-38057644

Palavras-chave

BDNF; Depression; Levomilnacipran; Neuroinflammation; Synaptic plasticity

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Mol Neurobiol Assunto da revista: BIOLOGIA MOLECULAR / NEUROLOGIA Ano de publicação: 2023 Tipo de documento: Article

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