Application of Cardiovascular Physiology to the Critically Ill Patient.
Crit Care Med
; 52(5): 821-832, 2024 05 01.
Article
em En
| MEDLINE
| ID: mdl-38126845
ABSTRACT
OBJECTIVES:
To use the ventricular pressure-volume relationship and time-varying elastance model to provide a foundation for understanding cardiovascular physiology and pathophysiology, interpreting advanced hemodynamic monitoring, and for illustrating the physiologic basis and hemodynamic effects of therapeutic interventions. We will build on this foundation by using a cardiovascular simulator to illustrate the application of these principles in the care of patients with severe sepsis, cardiogenic shock, and acute mechanical circulatory support. DATA SOURCES Publications relevant to the discussion of the time-varying elastance model, cardiogenic shock, and sepsis were retrieved from MEDLINE. Supporting evidence was also retrieved from MEDLINE when indicated. STUDY SELECTION, DATA EXTRACTION, ANDSYNTHESIS:
Data from relevant publications were reviewed and applied as indicated.CONCLUSIONS:
The ventricular pressure-volume relationship and time-varying elastance model provide a foundation for understanding cardiovascular physiology and pathophysiology. We have built on this foundation by using a cardiovascular simulator to illustrate the application of these important principles and have demonstrated how complex pathophysiologic abnormalities alter clinical parameters used by the clinician at the bedside.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Choque Cardiogênico
/
Sepse
Limite:
Humans
Idioma:
En
Revista:
Crit Care Med
Ano de publicação:
2024
Tipo de documento:
Article