Oral Malassezia infection co-occurring with tinea versicolor: metagenomic sequencing of the saliva.
Oral Surg Oral Med Oral Pathol Oral Radiol
; 137(3): e45-e52, 2024 03.
Article
em En
| MEDLINE
| ID: mdl-38155006
ABSTRACT
Malassezia is a lipid-dependent cutaneous symbiotic fungal genus associated with tinea versicolor. Here, we first present a rare case of a young tinea versicolor patient with oral manifestations presenting as white strips, patches, and pigmentation. The patient had a family history of tinea versicolor and a habit of frequent intake of cream. Histopathologic features and periodic acid-schiff staining of oral lesion indicated oral infection with round budding yeasts with short hyphae. Saliva metagenomic sequencing identified Malassezia and demonstrated the upregulated amount, diversity and activity of inflammatory bacteria. The clinical manifestations of oral Malassezia infection and changes in bacterial communities shed light on the pathogenic role of Malassezia in oral mucosa. In conclusion, we report the first oral Malassezia infection, which broadens the pathogenic cognitive scope of Malassezia and highlights the value of molecular techniques in the diagnostic process.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tinha Versicolor
/
Malassezia
Limite:
Humans
Idioma:
En
Revista:
Oral Surg Oral Med Oral Pathol Oral Radiol
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China