Association between grip strength and walking pace with incidence of degenerative cervical myelopathy: a UK biobank observational study.
Eur Spine J
; 2024 Jul 09.
Article
em En
| MEDLINE
| ID: mdl-38980365
ABSTRACT
PURPOSE:
This study investigates the association between handgrip strength, walking pace, and the incidence of degenerative cervical myelopathy (DCM) using the UK Biobank dataset.METHODS:
We analyzed data from 364,716 UK Biobank participants without prior neurological conditions. Handgrip strength was measured with a dynamometer, and walking pace was self-reported. Cox proportional hazards models assessed hazard ratios (HRs) and 95% confidence intervals (CIs) for DCM development.RESULTS:
The cohort, with an average age of 56.2 years (SD, 8.1) and 47.4% male, was followed for a median of 12.6 years. During this period, 3,993 participants (1.1%) developed DCM. A significant inverse correlation was found between handgrip strength and DCM incidence (P for trend < 0.001), with decreasing HRs for DCM across quartiles of increasing grip strength HRs were 0.70 (95% CI 0.64-0.76), 0.62 (95% CI 0.57-0.68), and 0.59 (95% CI 0.54-0.66) for the second, third, and fourth quartiles, respectively. Participants with average or brisk walking paces had a lower DCM risk (HR, 0.55; 95% CI 0.50-0.61 and HR, 0.48; 95% CI 0.43-0.54) compared to slow walkers. The greatest risk reduction was in those with both higher handgrip strength and faster pace (HR, 0.39; 95% CI 0.34-0.44).CONCLUSIONS:
Handgrip strength and walking pace are inversely associated with DCM incidence, suggesting their potential as cost-effective screening tools for identifying individuals at risk for DCM.
Texto completo:
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Base de dados:
MEDLINE
Idioma:
En
Revista:
Eur Spine J
Assunto da revista:
ORTOPEDIA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China