Orthostatic Ex-Vivo Lung Perfusion (EVLP): A Proof of Concept.
Transpl Int
; 37: 13178, 2024.
Article
em En
| MEDLINE
| ID: mdl-39144835
ABSTRACT
The key goal in lung donation remains the improvement of graft preservation with the ultimate objective of increasing the number and quality of lung transplants (LTx). Therefore, in recent years the field of graft preservation focused on improving outcomes related to solid organ regeneration and restoration. In this contest Ex-Vivo Lung Perfusion (EVLP) plays a crucial role with the purpose to increase the donor pool availability transforming marginal and/or declined donor lungs suitable for transplantation. Aim of this proof of concept is to test the safety, suitability and feasibility of a new tilting dome for EVLP designed considering the dorsal lung areas as the "Achilles' heel" of the EVLP due to a more fluid accumulation than in the supine standard position.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Preservação de Órgãos
/
Perfusão
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Transplante de Pulmão
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Estudo de Prova de Conceito
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Pulmão
Limite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Transpl Int
Assunto da revista:
TRANSPLANTE
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Itália