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Orthostatic Ex-Vivo Lung Perfusion (EVLP): A Proof of Concept.
Boffini, Massimo; Costamagna, Andrea; Marro, Matteo; Simonato, Erika; Cassoni, Paola; Bertero, Luca; Fanelli, Vito; Barbero, Cristina; Brazzi, Luca; Rinaldi, Mauro.
Afiliação
  • Boffini M; Cardiac Surgery Division, Surgical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, Italy.
  • Costamagna A; Anesthesiology and Intensive Care Division, Surgical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, Italy.
  • Marro M; Cardiac Surgery Division, Surgical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, Italy.
  • Simonato E; Cardiac Surgery Division, Surgical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, Italy.
  • Cassoni P; Pathology Unit, Medical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, Italy.
  • Bertero L; Pathology Unit, Medical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, Italy.
  • Fanelli V; Anesthesiology and Intensive Care Division, Surgical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, Italy.
  • Barbero C; Cardiac Surgery Division, Surgical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, Italy.
  • Brazzi L; Anesthesiology and Intensive Care Division, Surgical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, Italy.
  • Rinaldi M; Cardiac Surgery Division, Surgical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, Italy.
Transpl Int ; 37: 13178, 2024.
Article em En | MEDLINE | ID: mdl-39144835
ABSTRACT
The key goal in lung donation remains the improvement of graft preservation with the ultimate objective of increasing the number and quality of lung transplants (LTx). Therefore, in recent years the field of graft preservation focused on improving outcomes related to solid organ regeneration and restoration. In this contest Ex-Vivo Lung Perfusion (EVLP) plays a crucial role with the purpose to increase the donor pool availability transforming marginal and/or declined donor lungs suitable for transplantation. Aim of this proof of concept is to test the safety, suitability and feasibility of a new tilting dome for EVLP designed considering the dorsal lung areas as the "Achilles' heel" of the EVLP due to a more fluid accumulation than in the supine standard position.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preservação de Órgãos / Perfusão / Transplante de Pulmão / Estudo de Prova de Conceito / Pulmão Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Transpl Int Assunto da revista: TRANSPLANTE Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Itália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preservação de Órgãos / Perfusão / Transplante de Pulmão / Estudo de Prova de Conceito / Pulmão Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Transpl Int Assunto da revista: TRANSPLANTE Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Itália