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MicroRNA-enriched exosome as dazzling dancer between cancer and immune cells.
Hsu, Chou-Yi; Ahmed, Abdulrahman T; Bansal, Pooja; Hjazi, Ahmed; Al-Hetty, Hussein Riyadh Abdul Kareem; Qasim, Maytham T; Sapaev, Ibrokhim; Deorari, Mahamedha; Mustafa, Yasser Fakri; Elawady, Ahmed.
Afiliação
  • Hsu CY; Thunderbird School of Global Management, Arizona State University Tempe Campus, Phoenix, Arizona 85004, USA.
  • Ahmed AT; Department of Nursing, Al-Maarif University College, Ramadi, AL-Anbar Governorate, Iraq.
  • Bansal P; Department of Biotechnology and Genetics, Jain (Deemed-to-be) University, Bengaluru, 560069, Karnataka, India.
  • Hjazi A; Department of Allied Healthcare and Sciences, Vivekananda Global University, Jaipur, Rajasthan, 303012, India.
  • Al-Hetty HRAK; Department of Medical Laboratory, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia.
  • Qasim MT; Department of Biology, College Of Education For Pure Sciences, University Of Anbar, Ramadi, Anbar, 31001, Iraq. hussin.riyadh@uoanbar.edu.iq.
  • Sapaev I; College of Health and Medical Technology, Al-Ayen University, Thi-Qar, 64001, Iraq.
  • Deorari M; Tashkent Institute of Irrigation and Agricultural Mechanization Engineers" National Research University, Tashkent, Uzbekistan.
  • Mustafa YF; School of Engineering, Central Asian University, Tashkent, 111221, Uzbekistan.
  • Elawady A; Western Caspian University, Scientific researcher, Baku, Azerbaijan.
J Physiol Biochem ; 2024 Sep 24.
Article em En | MEDLINE | ID: mdl-39316240
ABSTRACT
Exosomes are widely recognized for their roles in numerous biological processes and as intercellular communication mediators. Human cancerous and normal cells can both produce massive amounts of exosomes. They are extensively dispersed in tumor-modeling animals' pleural effusions, ascites, and plasma from people with cancer. Tumor cells interact with host cells by releasing exosomes, which allow them to interchange various biological components. Tumor growth, invasion, metastasis, and even tumorigenesis can all be facilitated by this delicate and complex system by modifying the nearby and remote surroundings. Due to the existence of significant levels of biomolecules like microRNA, exosomes can modulate the immune system's stimulation or repression, which in turn controls tumor growth. However, the role of microRNA in exosome-mediated communication between immunological and cancer cells is still poorly understood. This study aims to get the most recent information on the "yin and yang" of exosomal microRNA in the regulation of tumor immunity and immunotherapy, which will aid current cancer treatment and diagnostic techniques.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: J Physiol Biochem Assunto da revista: BIOQUIMICA / FISIOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: J Physiol Biochem Assunto da revista: BIOQUIMICA / FISIOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos