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The aim of this animal study was to compare the primary/secondary stability and micro-CT bone and tissue volumes of implants that were immersed in Limosilactobacillus reuteri, cholecalciferol-D3 (vitamin D) and injectable platelet-rich fibrin (i-PRF) suspensions/solutions before placement in bone. 40 implants (10 in each group) were placed in the iliac crest of 5 sheep. The implants were immersed in L. reuteri, vitamin D or i-PRF solutions for five minutes before placement or left unsoaked as controls. Implant stability was determined by ISQ values and bone volume around implants was histomorphometrically analysed by micro-CT evaluation. At 4 weeks, implants in the L. reuteri group showed the highest secondary stability and 2- and 3D BV/TV values. Both L. reuteri and vitamin D immersed implants had higher osseointegration values compared to the implants in the i-PRF group and controls. There were no statistical differences between L. reuteri and vitamin D immersed implants. Within the limits of the study, the results suggest that immersing implants in L. reuteri or vitamin D suspensions/solutions before implant placement in bone may have beneficial effects on osseointegration.
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OBJECTIVE: This study investigates the biomechanical effects of graft width and chondrolabral junction (CLJ) preservation on the labral suction seal in a bovine hip model and aims to validate this model as a practical alternative for hip biomechanical research by comparing it with human cadaver studies. MATERIALS AND METHODS: Twenty hips from two-year-old male bovines were divided into two main groups: CLJ preserved (CLJ+) and CLJ excised (CLJ-). These groups were further divided into eight subgroups: Group 1 with an intact labrum; Group 2 with labrum excision preserving CLJ; Groups 3 and 4 with labral reconstruction on preserved CLJ using 4.5 mm and 9 mm grafts, respectively; Group 5 with a labral tear at 12 to 3 o'clock position without CLJ preservation; Group 6 with complete labrum excision without CLJ preservation; and Groups 7 and 8 with labral reconstruction on excised CLJ using 4.5 mm and 9 mm grafts. Mechanical tests measuring compression and distraction forces were conducted, recording force-displacement values. RESULTS: Both CLJ+ and CLJ- groups showed that labrum excision resulted in the lowest distraction forces, emphasizing labral integrity. Notably, reconstruction with 9 mm grafts improved distraction forces more than 4.5 mm grafts (p<0.001). The change in distraction forces from intact to excised stages was nearly significant between CLJ+ and CLJ- groups (Δ Intact-excised: CLJ+ vs. CLJ-: 92 N vs. 105 N, p=0.08). Distraction forces were measured at 206±27 Newtons in the CLJ preserved group and 186±24 Newtons in the resected group. CONCLUSIONS: This study demonstrates that increasing the width of the graft, despite being approximately half and a quarter of the native labrum's size, significantly enhances the distraction force in labral reconstruction within a bovine hip model. This improvement is more pronounced than the effects of preserving the CLJ, highlighting the critical role of graft size in maintaining the biomechanical integrity of the labral suction seal.
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Articulação do Quadril , Animais , Bovinos , Masculino , Fenômenos Biomecânicos , Articulação do Quadril/cirurgia , Cartilagem Articular/cirurgia , Humanos , Modelos AnimaisRESUMO
The invasive tetraploid Cirsium vulgare hybridizes with both Cirsium and Lophiolepis. Its conflicted position in molecular phylogenies, and its peculiar combination of morphological, anatomical, and genomic features that are alternatively shared with representatives of Cirsium or Lophiolepis, strongly suggest its intergeneric hybrid origin. Genetic relationships of C. vulgare (8 samples) with genus Lophiolepis (11 species) and other representatives of genus Cirsium (12 species) were evaluated using restriction site-associated DNA sequencing (RADseq) and examined using analytical and imaging approaches, such as NeighborNet, Heatmap, and STRUCTURE, to identify nuclear genomes admixture. Estimation of the intensity of spontaneous hybridization within and between Cirsium and Lophiolepis was based on herbarium revisions and published data for all reported hybrids pertinent to taxa currently included in Cirsium or Lophiolepis. The genome of any examined Cirsium species is more similar to C. vulgare than to any Lophiolepis species, and vice versa. The nuclear genome of the tetraploid C. vulgare is composed of two equivalent parts, each attributable either to Lophiolepis or to Cirsium; the organellar RADseq data clustered C. vulgare with the genus Cirsium. Spontaneous hybridization between Cirsium and Lophiolepis is significantly less intensive than within these genera. Our analyses provide compelling evidence that the invasive species C. vulgare has an allotetraploid intergeneric origin, with the maternal parent from Cirsium and the paternal from Lophiolepis. For the purpose of delimiting monophyletic genera, we propose keeping Lophiolepis separate from Cirsium and segregating C. vulgare into the hybridogenous genus Ascalea.
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Cirsium , Genoma de Planta , Hibridização Genética , Tetraploidia , Cirsium/genética , Genoma de Planta/genética , Filogenia , Espécies Introduzidas , Análise de Sequência de DNARESUMO
INTRODUCTION: The purpose of this in vitro study was to evaluate the dimensional accuracy, trueness, and precision of vinyl siloxane ether (VSXE) and polyvinylsiloxane (PVS) impression materials using different impression techniques. MATERIAL AND METHODS: A three-dimensional (3D) printed mandibular model with implants and metal rods served as the reference model. Impressions were taken in custom trays, resulting in four groups: PVS-closed-tray, VSXE-closed-tray, PVS-open-tray, and VSXE-open-tray. The reference model and impressions were scanned and analyzed using 3D analysis software to assess the trueness and precision within each group. RESULTS: There was significant difference in trueness between the groups, with PVS closed tray showing a higher deviation than VSXE-closed-tray and PVS-open-tray. VSXE-open-tray had the lowest deviation, which was statistically significant. In terms of precision, PVS-closed-tray showed the highest deviation, while no significant differences were found among the other groups. CONCLUSIONS: VSXE impression material with an open tray technique consistently demonstrated the highest levels of accuracy and precision. Conversely, PVS impression material with a closed tray technique yielded less favorable results. CLINICAL RELEVANCE: Better understanding of trueness and precision of new impression materials with new impression techniques will increase their clinical effectiveness.
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Materiais para Moldagem Odontológica , Técnica de Moldagem Odontológica , Revestimento de Dentadura , Mandíbula , Polivinil , Siloxanas , Materiais para Moldagem Odontológica/química , Siloxanas/química , Humanos , Prótese Dentária Fixada por Implante , Impressão Tridimensional , Técnicas In Vitro , Modelos DentáriosRESUMO
OBJECTIVES: In-office and lab milled prostheses are the staple for indirect restorations. It is therefore critical to determine their long-term bonding durability. METHODS: CAD/ CAM blocks of two classes of restorative materials: 1) a nano-ceramic reinforced polymer matrix (NCPM) and, 2) a polymer-infiltrated ceramic network (PICN) were bonded using four different universal adhesives (UA) and silane systems. A lithium disilicate glassceramic (LDS) was used as a reference. The blocks were bisected and bonded with different UA/resin-cement pairs. Bonded blocks were then cut into 1.0x1.0x12.0 mm bar specimens for microtensile bond testing. Half the bars were subjected to bond strength testing immediately and the other half after aging by 50,000 thermal cycles between 5°C and 55°C. ANOVA and post-hoc tests were used to compare mean bond strength among groups. RESULTS: NCPM presented consistently high bond strength regardless of bonding techniques, while the bond strength of PICN and LDS were lower when bonded with UA relative to traditional silanes. The more hydrophilic UA produced higher bond strengths. DISCUSSION: Glass-ceramics exhibited lower bond strength with UA than the conventional etch-rinse-silane techniques. However, UAs preserved bonding interface in the long-term. SIGNIFICANCE: NCPM displayed superior bond strength relative to PICN and LDS regardless of the type of adhesives and bonding techniques.
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INTRODUCTION: This study aims to investigate the effect of different particle sizes and pressures on the shear bond strength (SBS) and the roughness (Ra) of polyetheretherketone. MATERIALS AND METHODS: A total of 117 polyetheretherketone specimens were fabricated and divided into a control (CN: no air-particle abrasion) and eight pre-treatment groups (air-abraded with 50- or 110-µm Al2O3 particles at 1(A), 1.5(B), 2(C), and 2.5(D) bar). The adhesive, Visio.link was used. Thermal aging was performed. Surface properties, SBS and failure mode were assessed. Data was analyzed by linear regression, Pearson correlation and Dunnett's T3 test for pairwise comparisons (p⟨0.05). RESULTS: The highest and lowest Ra were found in the 110D and CN groups respectively, and the highest SBS results were obtained from the 50B group. Pressure and particle size showed significant difference on the investigated properties (p⟨0.001). Only adhesive failure was observed in the CN, and resin cohesive failure was observed in addition to adhesive failure in the overall study groups. CONCLUSION: The air-borne particle abrasion procedures and the adhesive material combination are critical to the strength of the polyetheretherketone bond. The combination of visio.link with the pre-treatment option of 50-µm Al2O3 particles applied at 1.5-bar pressure delivered the most favorable results.
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Benzofenonas , Cetonas , Teste de Materiais , Tamanho da Partícula , Polietilenoglicóis , Polímeros , Pressão , Propriedades de Superfície , Cetonas/química , Polietilenoglicóis/química , Resistência ao Cisalhamento , Colagem Dentária , Análise do Estresse DentárioRESUMO
This case report compares a conventional and a digital workflow for manufacturing metal frameworks for maxillary and mandibular removable partial dentures (RPDs). Two sets of maxillary and mandible RPDs were produced. The metal framework of one set of RPDs was produced conventionally using the lost wax casting technique. Intraoralscanning and computer-aided designing (CAD) were used to fabricate the metal frameworks of the other set of RPDs using direct metal laser sintering (DMLS) technology. The accuracy of fit of the two sets of RPDs was evaluated after 3 months using replica models. Patient satisfaction was assessed. Two years later, the fit accuracy of the DMLS prosthesis and patient satisfaction were re-evaluated. The accuracy of fit in the maxillary RPD with the DLMS manufactured metal framework showed better results in all areas except areas of rests (457 vs. 421 µm) and the major connector (850 vs. 512 µm). The mandibular RPD with DLMS manufactured metal framework showed only in the areas of the reciprocal arm and major connector better fit accuracy compared to the conventional RPD. The patient satisfaction with the DLMS manufactured RPDs was rated equally to the conventional one. The use of digital technologies in manufacturing RPDs seems promising regarding accuracy and patient satisfaction.
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Desenho Assistido por Computador , Prótese Parcial Removível , Humanos , Satisfação do Paciente , Mandíbula , MaxilaRESUMO
There is a lack of reports in the literature on the long-term clinical performance of ultratranslucent zirconia, especially considering its use in manufacturing monolithic veneers. The purpose of this case series is to describe the aesthetic treatment steps of three patients with minimally invasive ultratranslucent zirconia veneers and to report the clinical findings up to five years. Three patients (woman: 2, man: 1; mean age: 30 years) unsatisfied with their dental aesthetics sought dental treatment. The treatment plan involved cementing ultratranslucent zirconia veneers. Air-abrasion was performed on the internal surface of zirconia with alumina particles coated by silica (silicatization), followed by silane and adhesive applications for the adhesive cementation. All veneers were adhesively cemented to enamel with resin cement (Variolink Esthetic, Ivoclar). The patients were clinically evaluated annually considering the Ryge modified/ California Dental Association criteria. After a mean follow-up of 4.33 years (4-5 years), a survival rate of 100% was detected for the 28 minimally invasive ultratranslucent zirconia veneers cemented in the 3 patients. There were no absolute failures such as debonding, veneer fracture, or secondary caries. Superficial marginal discoloration was observed in one element (maxillary left lateral incisor) of one patient. Ultratranslucent zirconia is a viable option for manufacturing veneers due to its excellent clinical performance and longevity. However, further long-term clinical studies are essential to consolidate this material as an option for esthetic restorations.
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Porcelana Dentária , Zircônio , Masculino , Feminino , Humanos , Adulto , Seguimentos , Zircônio/uso terapêutico , CimentaçãoRESUMO
INTRODUCTION: The aim of this systematic review was to assess the literature reporting on the failure rates, survival rates and complication rates and patient reported outcome measures (PROMs) of anterior full (FC) or partial (PC) coverage single tooth restorations after a mean observation period of at least 3 years. METHODS: Systematic search was conducted using the electronic databases: MEDLINE, EMBASE and Cochrane library. Data regarding survival (restoration failure) and complication rates and PROMs were extracted and presented descriptively. RESULTS: Altogether 42 studies were included in the analysis (28 with FC, 12 with PC and 2 with both types of restorations). For FC restorations the estimated annual failure rate was 0.72 (95%CI: 0.33-1.57), resulting in a 5-year survival rate of 96.4% (95%CI: 92.4-98.3). For PC restorations, the estimated annual failure rate was 0.62 (95%CI: 0.27-1.46), resulting in a 5-year survival rate of 96.9% (95%CI: 93.0-98.7). There was no significant difference between the groups regarding survival or technical complications, while significantly fewer biological complications were observed with PC compared to FC restorations (test for subgroup differences, p=0.01). CONCLUSIONS: FC and PC restorations showed high 5-year survival rates but the teeth restored with FC restorations may be more prone to biological complications.
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OBJECTIVES: The aim of this systematic review and meta-analysis is to assess the comparative clinical success and survival of intracoronal indirect restorations using gold, lithium disilicate, leucite, and indirect composite materials. MATERIAL AND METHODS: This systematic review and meta-analysis were conducted following the Cochrane Handbook for Systematic Reviews of Interventions and PRISMA guidelines. The protocol for this study was registered in PROSPERO (registration number: CRD42021233185). A comprehensive literature search was conducted across various databases and sources, including PubMed/Medline, Embase, Cochrane Library, Web of Science, ClinicalTrials.gov, and gray literature. A total of 7826 articles were screened on title and abstract. Articles were not excluded based on the vitality of teeth, the language of the study, or the observation period. The risk difference was utilized for the analyses, and a random-effects model was applied. All analyses were conducted with a 95% confidence interval (95% CI). The calculated risk differences were derived from the combined data on restoration survival and failures obtained from each individual article. The presence of heterogeneity was assessed using the I2 statistic, and if present, the heterogeneity of the data in the articles was evaluated using the non-parametric chi-squared statistic (p < 0.05). RESULTS: A total of 12 eligible studies were selected, which included 946 restorations evaluated over a minimum observation period of 1 year and a maximum observation period of 7 years. Results of the meta-analysis indicated that intracoronal indirect resin composite restorations have an 18% higher rate of failure when compared to intracoronal gold restorations over 5-7 years of clinical service (risk difference = - 0.18 [95% CI: - 0.27, - 0.09]; p = .0002; I2 = 0%). The meta-analysis examining the disparity in survival rates between intracoronal gold and leucite restorations could not be carried out due to methodological differences in the studies. CONCLUSIONS: According to the currently available evidence, medium-quality data indicates that lithium disilicate and indirect composite materials demonstrate comparable survival rates in short-term follow-up. Furthermore, intracoronal gold restorations showed significantly higher survival rates, making them a preferred option over intracoronal indirect resin-composite restorations. Besides that, the analysis revealed no statistically significant difference in survival rates between leucite and indirect composite restorations. The short observation period, limited number of eligible articles, and low sample size of the included studies were significant limitations. CLINICAL SIGNIFICANCE: Bearing in mind the limitations of the reviewed literature, this systematic review and meta-analysis help clinicians make evidence-based decisions on how to restore biomechanically compromised posterior teeth.
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Silicatos de Alumínio , Porcelana Dentária , Resinas Compostas , OuroRESUMO
OBJECTIVES: The purpose of this study was to investigate the oxidative stress cycle consisting of reactive oxygen molecules (ROS), glutathione (GSH) and glutathione S-transferase (GST) in caries-related pulp inflammation. METHODOLOGY: Fifty-four pulp tissue samples were collected from healthy donors with the diagnosis of reversible pulpitis, symptomatic irreversible pulpitis, and healthy pulp. Twelve pulp samples from each group were homogenized and total protein, ROS, GSH, and GST were measured by spectrophotometer. The remaining 6 samples from each group were prepared for paraffin block and used for the histopathologic and immunohistochemical evaluation of oxidative stress parameters and TUNEL labeling. Data were analyzed statistically. RESULTS: The results revealed that total protein levels significantly decreased; however, ROS levels increased in both reversible and irreversible pulpitis compared to the healthy pulp (p < 0.01). Also, as inflammation increases, GST enzyme levels decrease while GSH levels increase significantly (p < 0.05). It was found that the number of TUNEL (+) cells was increased in irreversible pulpitis samples compared to healthy and reversible pulpitis groups (p < 0.05). GSTP1 and GSH immunoreactivity were also observed in irreversible pulpitis samples. CONCLUSIONS: It has been revealed that caries-related inflammation alters the oxidative stress cycle in dental pulp tissue. The increase in GSH levels in the inflamed dental pulp due to the increase in ROS levels may improve the defensive ability of the dental pulp. CLINICAL RELEVANCE: There is a relationship between oxidative stress and inflammation. Control of excessive oxidative stress in pulpitis can stimulate reparative and regenerative processes. The present findings may provide an overview of the management of oxidative stress in cases with pulpitis during regenerative treatments.
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Cárie Dentária , Pulpite , Humanos , Polpa Dentária/metabolismo , Espécies Reativas de Oxigênio/metabolismo , Inflamação/patologia , Cárie Dentária/patologia , Estresse OxidativoRESUMO
The chemomechanical cleaning of the root canal system is performed using manual and rotary files. This study aimed to compare the effect of ProTaper, Reciproc and HyFlex rotary files considering 2.5% sodium hypochlorite and 2% chlorhexidine (CHX) as irrigating solutions on apical extrusion of intracanal debris. Single-canal mandibular premolars (N=165) were evaluated. The teeth were divided into 6 experimental groups (N=25) for root canal instrumentation using 3 file systems, (Reciproc, HyFlex and ProTaper) and two irrigation solutions, namely 2.5% sodium hypochlorite or 2% CHX. Fifteen teeth were also assigned into three control groups (n=5) with saline as irrigation solution. Eppendorf tubes were weighed and the teeth were placed inside. The canals were instrumented and the tubes weighed to determine the dry weight of extruded debris. Data were analyzed using one-way ANOVA and Bonferroni test (α=0.05). The mean amount of extruded debris using the sodium hypochlorite solution was significantly higher than other irrigating solutions (p⟨0.001). The mean amount of extruded debris using the Reciproc file system was significantly higher compared to ProTaper and HyFlex (p⟨0.001). The use of the sodium hypochlorite solution, single-file systems and reciprocal movement are associated with higher debris extrusion and might be associated with higher risk of postoperative pain.
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Preparo de Canal Radicular , Hipoclorito de Sódio , Clorexidina , Cavidade Pulpar/cirurgia , Ápice Dentário/cirurgiaRESUMO
To assess the clinical periodontal status of abutment teeth in regards of different design components of distal-extension removable partial dentures. Subjects (N=100) with acrylic or cobalt-chromium distal-extension removable partial dentures were enrolled and their periodontal parameters plaque and gingival indices [PI, GI], probing depths [PD], clinical attachment loss [CAL] and a mobility index [MI] evaluated. Denture base type, major connector, occlusal rests position, design of direct retainers, retention, stability and denture wearing habits were further evaluated. Acrylic RPDs were associated with higher mean±SE PI [1.70±0.74], GI [1.76±0.55], PD scores [2.47±1.02 mm] and CAL values [4.46±2.11 mm] compared to CO-CR RPDs [p⟨0.05]. For abutments, the PI [1.6±0.83], GI [1.72±0.57], PD [2.32±1.03] and CAL [4.26±2.08] were higher than their non-abutments counterparts [p⟨0.05]. CAL scores were found to be significantly higher for mandibular abutments compared to maxillary ones [P=0.002]. The highest PI [1.83±1.10] and GI [2.00±0.00] scores were associated with lingual bars and horse-shoe connectors, respectively. Full palatal coverage and lingual plates were associated with the highest PD [2.80±0.48] and CAL [4.70±0.37] scores. Acrylic RPDs, type of major connector, wrought wire clasps and distal occlusal rests may be considered as risk factors for periodontal disease progression in distal-extension removable partial denture wearers.
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Prótese Parcial Removível , Doenças Periodontais , Dente , Humanos , Prótese Parcial Removível/efeitos adversos , Estudos Transversais , Dente Suporte , Doenças Periodontais/etiologia , Retenção de Dentadura/efeitos adversosRESUMO
This study evaluated the effect of the thickness and translucency of lithium disilicatebased glass ceramics on resin composite substrates on color change and masking effect. Laminate veneers were fabricated using IPS e.max CAD (A1) blocks with two different light transmittance values (High translucent [HT], Low translucent [LT]). Slices of two different thicknesses (0.3 mm, 0.5 mm) were obtained (n=10) and laminate veneers were cemented on the resin composite substrates of two different shades (A2, A3.5). The color change (ΔE values) was evaluated with the CIELab color system using a spectrophotometer, while the masking effect was calculated. The data were analyzed using independent-samples t-test and two-way analysis of variance. The ceramic thickness and translucency had a significant effect on final color and masking. When HT was used, and the laminate veneer thickness decreased (0.3 mm), the masking effect in ΔE values were lower (p⟨0.05). The ΔE values (⟩3.7) were clinically unacceptable. With the increase in thickness, translucency of porcelain laminate veneers decreases showing better color masking ability. Veneer thickness seems to be more effective on the restoration's masking ability than the shade of the substrate and translucency. Cinically, in case a 0.5-mm or thinner laminate veneer is planned, tooth color, resin cement and ceramic type should be considered.
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Porcelana Dentária , Facetas Dentárias , Cor , Teste de Materiais , Cerâmica , Cimentos de Resina , Resinas CompostasRESUMO
OBJECTIVES: The objective is to evaluate the long-term clinical survival and performance of direct and indirect resin composite restorations replacing cusps in vital upper premolars. METHODS: Between 2001 and 2007, 176 upper premolars in 157 patients were restored with 92 direct and 84 indirect resin composite restorations as part of an RCT. Inclusion criteria were fracture of the buccal or palatal cusp of vital upper premolars along with a class II cavity or restoration in the same tooth. RESULTS: Forty patients having 23 direct and 22 indirect composite restorations respectively, were lost to follow-up (25.6%). The cumulative Kaplan-Meier survival rates were 63.6% (mean observation time: 15.3 years, SE 5.6%) with an AFR of 2.4% for direct restorations and 54.5% (mean observation time: 13.9 years, SE: 6.4%) with an AFR of 3.3% for indirect restorations. The Cox regression analysis revealed a statistically significant influence of the patient's age at placement on the survival of the restoration (HR 1.036, p = 0.024), the variables gender, type of upper premolar, type of restoration, and which cusp involved in the restoration had no statistically significant influence. Direct composite restorations failed predominantly due to tooth fracture, indirect restorations primarily by adhesive failure (p < 0.05). SIGNIFICANCE: There was no statistically significant difference in survival rates between direct and indirect composite cusp-replacing restorations. Both direct and indirect resin composite cusp-replacing restorations are suitable options to restore compromised premolars. The longer treatment time and higher costs for the indirect restoration argue in favor of the direct technique.
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Preparo da Cavidade Dentária , Fraturas dos Dentes , Humanos , Dente Pré-Molar , Seguimentos , Preparo da Cavidade Dentária/métodos , Resinas Compostas , Restauração Dentária Permanente/métodos , Falha de Restauração DentáriaRESUMO
This study evaluated the clinical performance of low-shrinkage bioactive resin composite compared with a conventional nanohybrid resin composite. A total of 35 patients (18 males, 17 females; mean age: 29±9 years old) received, randomly, 35 pairs of fillings restored with either low-shrinkage bioactive material employing Giomer filler technology (Beautifil II LS, Shofu Inc, Kyoto, Japan) or conventional nanohybrid resin composite (Clearfil Majesty Posterior, Kuraray, Japan) in Class I and Class II cavities. Two operators made all the restorations using the corresponding adhesive resins: FL-Bond II (Shofu Inc) and Clearfil SE Bond (Kuraray), according to each manufacturer's instructions. Two calibrated operators evaluated the restorations two weeks after placement (baseline), at six months, and at one and two years using FDI criteria (Scores 1-5). Data were analyzed using the McNemar test (α=0.05). Mean observation time was 27.4 ± 4.1 months (min=20.8; max=33.7). In both groups, according to FDI criteria, the restorations were mostly rated with best scores (Score 1 or 2) for biological, functional, and optical parameters. For one filling in the group restored with nanohybrid resin composite, a small and localized secondary caries lesion was observed and monitored at the one- and two-year follow-ups. One restoration in the low-shrinkage Giomer restorative group was accepted as a failure due to retention loss. Over the two-year follow-up, both the Giomer and the nanohybrid resin composite restorations' performance was clinically acceptable.
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Cárie Dentária , Restauração Dentária Permanente , Adulto , Feminino , Humanos , Masculino , Adulto Jovem , Resinas Compostas/uso terapêutico , Resinas Compostas/química , Cárie Dentária/terapia , Adaptação Marginal Dentária , Estudos ProspectivosRESUMO
Two different restoration materials, an alkasite-based resin composite and a resinmodified glass ionomer cement were used to assess restoration of non-carious cervical dental lesions. This split mouth randomized controlled trial included 40 patients. After randomization both sides of the dental arch were restored with either an alkasite-based (Cention N, Ivoclar Vivadent) or a resin-modified glass ionomer cement (Voco GmbH) restoration. The placed fillings were evaluated by blinded additional operators 1, 6 months and 1 year after to the USPHS criteria (retention, marginal integrity and discoloration, anatomical form and secondary caries). Data were analyzed using Kendall's Coefficient of Concordance test and Chi-square tests using SPSS software (SPSS Inc., Version 20) (P=0.05). As for retention and anatomic form both materials performed similar after one month. However, the retention and anatomic form for alkasite based restorative Cention showed significantly better results after 6 months (p=0.013/p=0.003) and one year (p=0.026/p=0.008). The resin modified glass ionomer restoration showed higher discoloration after 6 months (p=0.025) and one year (p=0.018), while Cention performed better regarding marginal integrity at all time intervals. No secondary caries occurred. Alkasite based restorative materials displayed superior technical, mechanical and aesthetical performance in a follow-up period of one year and can therefore be recommended as an alternative to resin-modified glass ionomer cements.
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Cárie Dentária , Restauração Dentária Permanente , Humanos , Restauração Dentária Permanente/métodos , Cimentos de Resina , Materiais Dentários , Resinas Compostas , Cimentos de Ionômeros de Vidro , Adaptação Marginal Dentária , SeguimentosRESUMO
This study investigated the effect of silane coupling agent and universal adhesive application on repair bond strength of resin-based composite after bur grinding. Microhybrid resin composite (Charisma Smart) blocks (N=80; 8x8x4 mm3) were prepared, aged (37°C; 1 month), roughened, etched and randomly divided into two groups. Silane was applied to half of the groups (Porcelain Primer, Bisco), before one of the following universal primers/adhesives was applied: a) Scotchbond Universal (3M), b) All-Bond Universal (Bisco), c) G-Premio Bond (GC), and d) Clearfil SE Bond (Kuraray). In each adhesive group half of the group was photo-polymerized. The blocks were repaired with the same size resin composite and segmented into beams. Half of the beams were subjected to micro-tensile bond test (1 mm/min), while the other half was aged (37°C; 6 months) prior to testing. Failure modes were analyzed using Scanning Electron Microscopy (SEM). Data were analyzed using repeated measures of ANOVA, Tukey's post-hoc, and paired t-tests (alpha=0.05). The silane application did not affect the repair bond strength regardless of photo-polymerization of the adhesive resin. The repair bond strength decreased significantly after 6 months when adhesive resin was not photopolymerized (p⟨0.05). Photo-polymerizing universal adhesives might ensure higher repair bond strength and its maintenance after aging.
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Colagem Dentária , Cimentos Dentários , Resinas Compostas/química , Teste de Materiais , Polimerização , Cimentos de Resina/química , Silanos/química , Propriedades de Superfície , Resistência à TraçãoRESUMO
Objective: This study aims to determine the prevalence of neuropathy in the prediabetic period. Design Subjects and Method: Informed consent was attained from the patients who volunteered to participate in the study after ethics committee approval was obtained. Patients under the age of 18, having vitamin B12 or folic acid deficiency, history of collagen tissue-rheumatological disease, chronic kidney failure, cirrhosis, ethylism, thyroid disease, autoimmune disease, malignancy, tuberculosis, type 1 or 2 diabetes mellitus and pregnant women were excluded from the study. Patients diagnosed with prediabetes were evaluated by the DN4 neuropathy complaint questionnaire. Neuropathy was diagnosed in patients having a score of four or more. For the statistical analyses Student t-test, Pearson chi-square test, and Fisher's exact test were performed using the NCSS program. Results: A total of 224 volunteers, 167 women and 57 men, were included in the study. The mean age of the participants was 51 and the mean level of hemoglobin A1C was 5.9. Neuropathy was detected in 45% of the cases. Especially in women, there was a significant increase in the frequency of neuropathy compared to men. The most common complaints found in our study were burning sensation and numbness in the extremities. Conclusions: Similar to diabetic patients, prediabetic patients also have a high rate of neuropathy. For the early diagnosis of neuropathy and to be treated promptly, screening tests such as DN4 should be performed for all prediabetic patients. According to the test results, advanced examinations such as EMG or biopsy should be performed earlier.