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1.
BMC Public Health ; 23(1): 526, 2023 03 20.
Artigo em Inglês | MEDLINE | ID: mdl-36941552

RESUMO

BACKGROUND: A randomised trial of European Fans in Training (EuroFIT), a 12-week healthy lifestyle program delivered in 15 professional football clubs in the Netherlands, Norway, Portugal, and the United Kingdom, successfully increased physical activity and improved diet but did not reduce sedentary time. To guide future implementation, this paper investigates how those effects were achieved. We ask: 1) how was EuroFIT implemented? 2) what were the processes through which outcomes were achieved? METHODS: We analysed qualitative data implementation notes, observations of 29 of 180 weekly EuroFIT deliveries, semi-structured interviews with 16 coaches and 15 club representatives, and 30 focus group discussions with participants (15 post-program and 15 after 12 months). We descriptively analysed quantitative data on recruitment, attendance at sessions and logs of use of the technologies and survey data on the views of participants at baseline, post program and after 12 months. We used a triangulation protocol to investigate agreement between data from difference sources, organised around meeting 15 objectives within the two research questions. RESULTS: We successfully recruited clubs, coaches and men to EuroFIT though the draw of the football club seemed stronger in the UK and Portugal. Advertising that emphasized getting fitter, club-based deliveries, and not 'standing out' worked and attendance and fidelity were good, so that coaches in all countries were able to deliver EuroFIT flexibly as intended. Coaches in all 15 clubs facilitated the use of behaviour change techniques and interaction between men, which together enhanced motivation. Participants found it harder to change sedentary time than physical activity and diet. Fitting changes into daily routines, planning for setbacks and recognising the personal benefit of behaviour change were important to maintain changes. Bespoke technologies were valued, but technological hitches frustrated participants. CONCLUSION: EuroFIT was delivered as planned by trained club coaches working flexibly in all countries. It worked as expected to attract men and support initiation and maintenance of changes in physical activity and diet but the use of bespoke, unstable, technologies was frustrating. Future deliveries should eliminate the focus on sedentary time and should use only proven technologies to support self-monitoring and social interaction. TRIAL REGISTRATION: ISRCTN81935608, registered 16/06/2015.


Assuntos
Futebol Americano , Futebol , Masculino , Humanos , Exercício Físico , Estilo de Vida Saudável , Portugal , Avaliação de Programas e Projetos de Saúde
2.
J Child Orthop ; 16(3): 183-190, 2022 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-35800653

RESUMO

Purpose: The purpose of the study was to assess the effect of further follow-up for children treated for developmental dysplasia of the hip, with normal clinical and radiological findings at 1-year time point. The effect was quantified by the number of hips with a pathologic deterioration up to 5 years. Methods: Among 47,289 children born in Sør-Trøndelag county in Norway between 2003 and 2015, 265 children had developmental dysplasia of the hip. Of these, 164 children (239 hips) treated for developmental dysplasia of the hip with normal clinical findings and normal acetabular index at the 1-year time point were included in the study. The number of hips with pathologic acetabular index at the 5-year time point were reported. The diagnostic uncertainty related to radiological measurements was quantified together with the effect of introducing a second radiographic measurement, the center edge angle. Results: A total of 239 treated hips were normal at the 1-year time point. At 5-year time point, 10 (4.2%) hips had a pathologic acetabular index measurement and none classified to have developmental dysplasia of the hip caused by measurement inaccuracy. Eight (3.3%) hips had pathologic center edge angle measurement. Four hips had both pathologic acetabular index and center edge angle measurements, with three later treated with surgery. The intra- and interobserver repeatability coefficients were within 3.1°-6.6°. Conclusion: The repeatability coefficient of the acetabular index measurements was high and no hips could be classified to have developmental dysplasia of the hip at the 5-year time point when taking this repeatability into account. Hips classified as pathologic combining acetabular index and center edge angle measurements were likely to be treated with surgery for residual dysplasia. We recommend further follow-up for these children. Level of evidence: level II.

3.
Int J Behav Nutr Phys Act ; 18(1): 166, 2021 12 20.
Artigo em Inglês | MEDLINE | ID: mdl-34930299

RESUMO

BACKGROUND: Increased physical activity (PA), reduced time spent sedentary (SED), healthier diet and reduced body weight may all have a positive impact on cardiometabolic risk. The relative importance of change in each of these variables on cardiometabolic risk, however, is unclear. We therefore sought to investigate the relative contributions of changes in PA, SED, diet and body weight on cardiometabolic risk. METHODS: This is a secondary analysis of data collected from the EuroFIT randomised controlled trial, which was a 12-week group-based lifestyle intervention for overweight middle-aged men delivered by coaches in football club stadia aiming to improve PA, SED, diet, and body weight. PA and SED were assessed by accelerometry, diet using the Dietary Instrument for Nutrition Education (DINE). An overall cardiometabolic risk score was derived from combining z-scores for glucose, HbA1c, insulin, lipids and blood pressure. In total, 707 men (from the overall cohort of 1113) with complete data for these variables at baseline and 12-month follow-up were included in the multivariable linear regression analyses. RESULTS: In multivariable analyses, change in number of steps (explaining 5.1% of R2) and dietary factors (less alcohol, fatty and sugary food, and more fruit and vegetables) (together explaining 4.5% of R2), but not changes in standing time or SED, were significantly associated with change in body weight. Changes in number of steps (R2 = 1.7%), fatty food score (R2 = 2.4%), and sugary food score (R2 = 0.4%) were significantly associated with change in cardiometabolic risk score in univariable models. However, in multivariable models which included changes in weight as well as changes in steps and dietary variables, change in weight explained a substantially larger proportion of the change in cardiometabolic risk score, explaining 14.1% of R2 (out of an overall model R2 of 19.0%). When baseline (as well as change) values were also included in the model, 38.8% of R2 for change in cardiometabolic risk score was explained overall, with 14.1% of R2 still explained by change in weight. CONCLUSION: Change in body weight, together with baseline cardiometabolic risk explained most of the change in cardiometabolic risk. Thus, the benefits of increasing physical activity and improving diet on cardiometabolic risk appear to act largely via an effect on changes in body weight. TRIAL REGISTRATION: International Standard Randomised Controlled Trials, ISRCTN-81935608. Registered 06052015. https://www.isrctn.com/ISRCTN81935608?q=&filters=recruitmentCountry:Portugal&sort=&offset=7&totalResults=92&page=1&pageSize=10&searchType=basic-search.


Assuntos
Doenças Cardiovasculares , Comportamento Sedentário , Doenças Cardiovasculares/prevenção & controle , Dieta , Exercício Físico/fisiologia , Humanos , Masculino , Pessoa de Meia-Idade , Sobrepeso
4.
PLoS One ; 16(11): e0259458, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34797842

RESUMO

This study mapped existing health-promotion provisions targeting adults in professional football clubs across England, the Netherlands, Norway, and Portugal, and explored motives behind the clubs' adoption of the European Fans in Training (EuroFIT) programme. We surveyed top-tier football clubs in the four countries and interviewed representatives from football clubs and the clubs' charitable foundation who delivered EuroFIT. The findings showed large between-country differences, with football clubs in England reporting far greater healthy lifestyle provision than other countries. Relatively few health-promotion programmes targeted adults, particularly in the Netherlands, Portugal, and Norway. Club representatives reported that the motives for adopting the EuroFIT programme often involved adhering to both the social objectives of the football club or club's foundation and business-related objectives. They viewed the scientific evidence and evaluation underpinning EuroFIT as helpful in demonstrating the value and potential future impact of both the programme and the clubs' wider corporate social responsibility provision.


Assuntos
Promoção da Saúde , Motivação , Adulto , Dieta Saudável , Europa (Continente) , Feminino , Futebol Americano , Humanos , Entrevistas como Assunto , Masculino , Pessoa de Meia-Idade , Avaliação de Programas e Projetos de Saúde , Participação dos Interessados/psicologia , Inquéritos e Questionários , Telefone , Adulto Jovem
5.
Int J Sports Physiol Perform ; 16(1): 37-44, 2021 01 01.
Artigo em Inglês | MEDLINE | ID: mdl-32604071

RESUMO

PURPOSE: To investigate the effect of a double-poling (DP) high-intensity aerobic interval-training (HIT) intervention performed without increasing total HIT volume. This means that regular HIT training (eg, running) was replaced by HIT DP. The aim was to explore whether this intervention could improve peak oxygen uptake in DP, the fractional utilization of maximal oxygen uptake (VO2max) in DP, oxygen cost of DP, maximal aerobic speed, and a 3-km DP time trial. METHODS: Nine non-specially-DP-trained cross-country skiers (intervention group) and 9 national-level cross-country skiers (control group) were recruited. All participants were tested for VO2max in running, peak oxygen uptake in DP, oxygen cost of DP, and time-trial performance before and after a 6-wk, 3-times-per-week HIT DP intervention. The intervention group omitted all regular HIT with HIT in DP, leaving the total weekly amount of HIT unchanged. RESULTS: Seven participants in each group completed the study. VO2max in running remained unchanged in both groups, whereas peak oxygen uptake in DP improved by 7.1% (P = .005) in the intervention group. The fractional utilization of VO2max in DP thus increased by 7.3% (P = .019), oxygen cost of DP by 9.2% (P = .047), maximal aerobic speed by 16.5% (P = .009), and time trial by 19.5% (P = .004) in the intervention group but remained unchanged in the control group. CONCLUSIONS: The results indicate that a 6-wk HIT DP intervention could be an effective model to improve DP-specific capacities, with maintenance of VO2max in running.


Assuntos
Desempenho Atlético/fisiologia , Consumo de Oxigênio , Esqui/fisiologia , Teste de Esforço , Treinamento Intervalado de Alta Intensidade , Humanos , Músculo Esquelético/fisiologia , Oxigênio , Corrida/fisiologia
7.
PLoS Med ; 16(2): e1002736, 2019 02.
Artigo em Inglês | MEDLINE | ID: mdl-30721231

RESUMO

BACKGROUND: Reducing sitting time as well as increasing physical activity in inactive people is beneficial for their health. This paper investigates the effectiveness of the European Fans in Training (EuroFIT) programme to improve physical activity and sedentary time in male football fans, delivered through the professional football setting. METHODS AND FINDINGS: A total of 1,113 men aged 30-65 with self-reported body mass index (BMI) ≥27 kg/m2 took part in a randomised controlled trial in 15 professional football clubs in England, the Netherlands, Norway, and Portugal. Recruitment was between September 19, 2015, and February 2, 2016. Participants consented to study procedures and provided usable activity monitor baseline data. They were randomised, stratified by club, to either the EuroFIT intervention or a 12-month waiting list comparison group. Follow-up measurement was post-programme and 12 months after baseline. EuroFIT is a 12-week, group-based programme delivered by coaches in football club stadia in 12 weekly 90-minute sessions. Weekly sessions aimed to improve physical activity, sedentary time, and diet and maintain changes long term. A pocket-worn device (SitFIT) allowed self-monitoring of sedentary time and daily steps, and a game-based app (MatchFIT) encouraged between-session social support. Primary outcome (objectively measured sedentary time and physical activity) measurements were obtained for 83% and 85% of intervention and comparison participants. Intention-to-treat analyses showed a baseline-adjusted mean difference in sedentary time at 12 months of -1.6 minutes/day (97.5% confidence interval [CI], -14.3-11.0; p = 0.77) and in step counts of 678 steps/day (97.5% CI, 309-1.048; p < 0.001) in favor of the intervention. There were significant improvements in diet, weight, well-being, self-esteem, vitality, and biomarkers of cardiometabolic health in favor of the intervention group, but not in quality of life. There was a 0.95 probability of EuroFIT being cost-effective compared with the comparison group if society is willing to pay £1.50 per extra step/day, a maximum probability of 0.61 if society is willing to pay £1,800 per minute less sedentary time/day, and 0.13 probability if society is willing to pay £30,000 per quality-adjusted life-year (QALY). It was not possible to blind participants to group allocation. Men attracted to the programme already had quite high levels of physical activity at baseline (8,372 steps/day), which may have limited room for improvement. Although participants came from across the socioeconomic spectrum, a majority were well educated and in paid work. There was an increase in recent injuries and in upper and lower joint pain scores post-programme. In addition, although the five-level EuroQoL questionnaire (EQ-5D-5L) is now the preferred measure for cost-effectiveness analyses across Europe, baseline scores were high (0.93), suggesting a ceiling effect for QALYs. CONCLUSION: Participation in EuroFIT led to improvements in physical activity, diet, body weight, and biomarkers of cardiometabolic health, but not in sedentary time at 12 months. Within-trial analysis suggests it is not cost-effective in the short term for QALYs due to a ceiling effect in quality of life. Nevertheless, decision-makers may consider the incremental cost for increase in steps worth the investment. TRIAL REGISTRATION: International Standard Randomised Controlled Trials, ISRCTN-81935608.


Assuntos
Exercício Físico/fisiologia , Promoção da Saúde/métodos , Aptidão Física/fisiologia , Avaliação de Programas e Projetos de Saúde/métodos , Comportamento Sedentário , Futebol/fisiologia , Adulto , Idoso , Europa (Continente)/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade
10.
Carbon Balance Manag ; 10: 18, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26246851

RESUMO

BACKGROUND: Anthropogenic uses of fire play a key role in regulating fire regimes in African savannas. These fires contribute the highest proportion of the globally burned area, substantial biomass burning emissions and threaten maintenance and enhancement of carbon stocks. An understanding of fire regimes at local scales is required for the estimation and prediction of the contribution of these fires to the global carbon cycle and for fire management. We assessed the spatio-temporal distribution of fires in miombo woodlands of Tanzania, utilizing the MODIS active fire product and Landsat satellite images for the past ~40 years. RESULTS: Our results show that up to 50.6% of the woodland area is affected by fire each year. An early and a late dry season peak in wetter and drier miombo, respectively, characterize the annual fire season. Wetter miombo areas have higher fire activity within a shorter annual fire season and have shorter return intervals. The fire regime is characterized by small-sized fires, with a higher ratio of small than large burned areas in the frequency-size distribution (ß = 2.16 ± 0.04). Large-sized fires are rare, and occur more frequently in drier than in wetter miombo. Both fire prevalence and burned extents have decreased in the past decade. At a large scale, more than half of the woodland area has less than 2 years of fire return intervals, which prevent the occurrence of large intense fires. CONCLUSION: The sizes of fires, season of burning and spatial extent of occurrence are generally consistent across time, at the scale of the current analysis. Where traditional use of fire is restricted, a reassessment of fire management strategies may be required, if sustainability of tree cover is a priority. In such cases, there is a need to combine traditional and contemporary fire management practices.

11.
Environ Monit Assess ; 186(3): 1765-80, 2014 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-24310365

RESUMO

Classifying multi-temporal image data to produce thematic maps and quantify land cover changes is one of the most common applications of remote sensing. Mapping land cover changes at the regional level is essential for a wide range of applications including land use planning, decision making, land cover database generation, and as a source of information for sustainable management of natural resources. Land cover changes in Lake Hawassa Watershed, Southern Ethiopia, were investigated using Landsat MSS image data of 1973, and Landsat TM images of 1985, 1995, and 2011, covering a period of nearly four decades. Each image was partitioned in a GIS environment, and classified using an unsupervised algorithm followed by a supervised classification method. A hybrid approach was employed in order to reduce spectral confusion due to high variability of land cover. Classification of satellite image data was performed integrating field data, aerial photographs, topographical maps, medium resolution satellite image (SPOT 20 m), and visual image interpretation. The image data were classified into nine land cover types: water, built-up, cropland, woody vegetation, forest, grassland, swamp, bare land, and scrub. The overall accuracy of the LULC maps ranged from 82.5 to 85.0 %. The achieved accuracies were reasonable, and the observed classification errors were attributable to coarse spatial resolution and pixels containing a mixture of cover types. Land cover change statistics were extracted and tabulated using the ERDAS Imagine software. The results indicated an increase in built-up area, cropland, and bare land areas, and a reduction in the six other land cover classes. Predominant land cover is cropland changing from 43.6 % in 1973 to 56.4 % in 2011. A significant portion of land cover was converted into cropland. Woody vegetation and forest cover which occupied 21.0 and 10.3 % in 1973, respectively, diminished to 13.6 and 5.6 % in 2011. The change in water body was very peculiar in that the area of Lake Hawassa increased from 91.9 km(2) in 1973 to 95.2 km(2) in 2011, while that of Lake Cheleleka whose area was 11.3 km(2) in 1973 totally vanished in 2011 and transformed into mud-flat and grass dominated swamp. The "change and no change" analysis revealed that more than one third (548.0 km(2)) of the total area was exposed to change between 1973 and 2011. This study was useful in identifying the major land cover changes, and the analysis pursued provided a valuable insight into the ongoing changes in the area under investigation.


Assuntos
Monitoramento Ambiental/métodos , Sistemas de Informação Geográfica , Lagos/química , Tecnologia de Sensoriamento Remoto , Agricultura , Conservação dos Recursos Naturais , Etiópia , Árvores , Urbanização , Áreas Alagadas
12.
J Pediatr ; 161(1): 146-51, 2012 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-22364819

RESUMO

OBJECTIVE: To study attitudes regarding life-saving interventions. STUDY DESIGN: An Internet questionnaire describing 6 patients of different ages needing resuscitation was sent to members of the Norwegian Pediatric Association (n = 676): a 24-week gestational age infant, a term infant, a 2-month-old infant, a 7-year, a 50-year, and an 80-year-old individual. Neonates had similar or better described outcomes than older patients. RESULTS: A total of 266 people responded (39.4%). The majority would resuscitate all the patients except the 80-year-old. The majority thought that resuscitation was in the best interest of the younger 5 patients, but fewer thought so for neonates (P < .05). Although the majority of the respondents thought that resuscitation was in the neonates' best interest (71% for 24-week-old and 75% for term infant), significantly more would accept comfort care at parental demand (62% for 24-week-old and 72% for term infant), unlike for other scenarios. Quality of life was used to justify decision making; 25% used the length of the life for neonates to motivate their answers. Patients were prioritized for resuscitation in the following order: 2-month-old infant, 7-year-old child with multiple disabilities, 50-year-old adult, the neonates, and lastly the 80-year-old individual. CONCLUSION: There are challenges in reconciling best interest and parental exercise of autonomy in pediatric life-or-death situations. Neonates seem to be devalued.


Assuntos
Atitude Frente a Saúde , Pais/psicologia , Autonomia Pessoal , Ressuscitação , Idoso de 80 Anos ou mais , Criança , Humanos , Lactente , Recém-Nascido , Pessoa de Meia-Idade , Inquéritos e Questionários
13.
Neuroradiology ; 53(6): 435-47, 2011 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-20857284

RESUMO

INTRODUCTION: To assess the diagnostic accuracy of microvascular leakage (MVL), cerebral blood volume (CBV) and blood flow (CBF) values derived from dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging (DSC-MR imaging) for grading of cerebral glial tumors, and to estimate the correlation between vascular permeability/perfusion parameters and tumor grades. METHODS: A prospective study of 79 patients with cerebral glial tumors underwent DSC-MR imaging. Normalized relative CBV (rCBV) and relative CBF (rCBF) from tumoral (rCBVt and rCBFt), peri-enhancing region (rCBVe and rCBFe), and the value in the tumor divided by the value in the peri-enhancing region (rCBVt/e and rCBFt/e), as well as MVL, expressed as the leakage coefficient K(2) were calculated. Hemodynamic variables and tumor grades were analyzed statistically and with Pearson correlations. Receiver operating characteristic (ROC) curve analyses were also performed for each of the variables. RESULTS: The differences in rCBVt and the maximum MVL (MVL(max)) values were statistically significant among all tumor grades. Correlation analysis using Pearson was as follows: rCBVt and tumor grade, r = 0.774; rCBFt and tumor grade, r = 0.417; MVL(max) and tumor grade, r = 0.559; MVL(max) and rCBVt, r = 0.440; MVL(max) and rCBFt, r = 0.192; and rCBVt and rCBFt, r = 0.605. According to ROC analyses for distinguishing tumor grade, rCBVt showed the largest areas under ROC curve (AUC), except for grade III from IV. CONCLUSION: Both rCBVt and MVL(max) showed good discriminative power in distinguishing all tumor grades. rCBVt correlated strongly with tumor grade; the correlation between MVL(max) and tumor grade was moderate.


Assuntos
Neoplasias Encefálicas/diagnóstico , Encéfalo/irrigação sanguínea , Circulação Cerebrovascular , Glioma/diagnóstico , Imageamento por Ressonância Magnética , Microvasos/patologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Encéfalo/patologia , Neoplasias Encefálicas/patologia , Meios de Contraste , Diagnóstico Diferencial , Feminino , Glioma/patologia , Humanos , Masculino , Microvasos/fisiopatologia , Pessoa de Meia-Idade , Gradação de Tumores , Perfusão , Estudos Prospectivos
14.
Eur J Radiol ; 80(2): 462-70, 2011 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-20708868

RESUMO

PURPOSE: Tumor grading is very important both in treatment decision and evaluation of prognosis. While tissue samples are obtained as part of most therapeutic approaches, factors that may result in inaccurate grading due to sampling error (namely, heterogeneity in tissue sampling, as well as tumor-grade heterogeneity within the same tumor specimen), have led to a desire to use imaging better to ascertain tumor grade. The purpose in our study was to evaluate the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), area under the curve (AUC), and accuracy of diffusion-weighted MR imaging (DWI), proton MR spectroscopic imaging (MRSI) or both in grading primary cerebral gliomas. MATERIALS AND METHODS: We performed conventional MR imaging (MR), DWI, and MRSI in 74 patients with newly diagnosed brain gliomas: 59 patients had histologically verified high-grade gliomas: 37 glioblastomas multiform (GBM) and 22 anaplastic astrocytomas (AA), and 15 patients had low-grade gliomas. Apparent diffusion coefficient (ADC) values of tumor and peritumoral edema, and ADC ratios (ADC in tumor or peritumoral edema to ADC of contralateral white matter, as well as ADC in tumor to ADC in peritumoral edema) were determined from three regions of interest. The average of the mean, maximum, and minimum for ADC variables was calculated for each patient. The metabolite ratios of Cho/Cr and Cho/NAA at intermediate TE were assessed from spectral maps in the solid portion of tumor, peritumoral edema and contralateral normal-appearing white matter. Tumor grade determined with the two methods was then compared with that from histopathologic grading. Logistic regression and receiver operating characteristic (ROC) curve analysis were performed to determine optimum thresholds for tumor grading. Measures of diagnostic examination performance, such as sensitivity, specificity, PPV, NPV, AUC, and accuracy for identifying high-grade gliomas were also calculated. RESULTS: Statistical analysis demonstrated a threshold minimum ADC tumor value of 1.07 to provide sensitivity, specificity, PPV, and NPV of 79.7%, 60.0%, 88.7%, and 42.9% respectively, in determining high-grade gliomas. Threshold values of 1.35 and 1.78 for peritumoral Cho/Cr and Cho/NAA metabolite ratios resulted in sensitivity, specificity, PPV, and NPV of 83.3%, 85.1%, 41.7%, 97.6%, and 100%, 57.4%, 23.1% and 100% respectively for determining high-grade gliomas. Significant differences were noted in the ADC tumor values and ratios, peritumoral Cho/Cr and Cho/NAA metabolite ratios, and tumoral Cho/NAA ratio between low- and high-grade gliomas. The combination of mean ADC tumor value, maximum ADC tumor ratio, peritumoral Cho/Cr and Cho/NAA metabolite ratios resulted in sensitivity, specificity, PPV, and NPV of 91.5%, 100%, 100% and 60% respectively. CONCLUSION: Combining DWI and MRSI increases the accuracy of preoperative imaging in the determination of glioma grade. MRSI had superior diagnostic performance in predicting glioma grade compared with DWI alone. The predictive values are helpful in the clinical decision-making process to evaluate the histologic grade of tumors, and provide a means of guiding treatment.


Assuntos
Neoplasias Encefálicas/diagnóstico , Imagem de Difusão por Ressonância Magnética/métodos , Glioma/diagnóstico , Espectroscopia de Ressonância Magnética/métodos , Área Sob a Curva , Ácido Aspártico/análogos & derivados , Ácido Aspártico/metabolismo , Neoplasias Encefálicas/metabolismo , Neoplasias Encefálicas/patologia , Colina/metabolismo , Creatina/metabolismo , Feminino , Glioma/metabolismo , Glioma/patologia , Humanos , Interpretação de Imagem Assistida por Computador , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Gradação de Tumores , Valor Preditivo dos Testes , Prótons , Curva ROC , Sensibilidade e Especificidade
15.
J Magn Reson Imaging ; 31(5): 1124-31, 2010 May.
Artigo em Inglês | MEDLINE | ID: mdl-20432347

RESUMO

PURPOSE: To investigate the contrast of three-dimensional balanced steady state free precession (3D bSSFP) in the two component T2 model and to apply the results to optimize 3D bSSFP for prostate imaging at 1.5 Tesla. MATERIALS AND METHODS: In each of seven healthy volunteers, six 3D bSSFP acquisitions were performed with flip angles (alpha) equally spaced between 10 degrees and 110 degrees . Predictions of signal and contrast were obtained from synthetic bSSFP images calculated from relaxation parameters obtained from a multi-spin-echo acquisition. One biexponential and two monoexponential models were applied. Measured and predicted signals were compared by simple linear regression. RESULTS: The measured contrast to signal ratio increased continuously with alpha. Mean R(2) for the biexponential model was almost constant for alpha in the range 50-110 degrees . The biexponential model was a better predictor of the measured signal than the monoexponential model. A monoexponential model restricted to the echoes TE = 50-125 ms performed similar to the biexponential model. The predicted contrast peaked at alpha between 50 degrees and 90 degrees . CONCLUSION: Prostate imaging with bSSFP benefited from high flip angles. The biexponential model provided good signal prediction while predictions from the monoexponential models are dependent on the range of TE used for T2 determination.


Assuntos
Algoritmos , Interpretação de Imagem Assistida por Computador/métodos , Imageamento Tridimensional/métodos , Imageamento por Ressonância Magnética/métodos , Modelos Anatômicos , Modelos Biológicos , Próstata/anatomia & histologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Simulação por Computador , Humanos , Aumento da Imagem/métodos , Masculino , Pessoa de Meia-Idade , Modelos Estatísticos , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
16.
J Magn Reson Imaging ; 28(5): 1166-72, 2008 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-18972358

RESUMO

PURPOSE: To investigate the T2 decay in prostate tissue for multiexponentiality and to assess how the biexponential model relates to established T2W contrast. MATERIALS AND METHODS: A 32-echo spin-echo sequence was performed on 16 volunteers. Six single-voxel decay curves were sampled from each prostate. Prediction accuracies were assessed by jackknifing for the mono-, bi-, and triexponential models. The differences were evaluated by cross-validated analysis of variance (CVANOVA). Multiple linear regression was performed to assess the relation between parameters in the biexponential model and the contrast in T2W images. RESULTS: Mono-, bi-, and triexponential models were preferred in 8 (10%), 72 (86%), and 4 (5%) cases, respectively. The biexponential short T2 was 64 msec (range 43 to 92 msec) and the long T2 was 490 msec (range 161 to 1319 msec). The fitted signal fraction, f, of the long T2 component was 27% (range 3% to 80%). The adjusted R(2) was 75.1% for the full regression model and decreased by 0.9%, 1.3%, and 39.2% when short T2, long T2, and f were removed from the model, respectively. CONCLUSION: Prostatic T2 decay was, in general, biexponential. The differences between the T2 components were large enough for accurate quantification. The T2W image contrast was primarily predicted by the biexponential signal fractions.


Assuntos
Algoritmos , Aumento da Imagem/métodos , Interpretação de Imagem Assistida por Computador/métodos , Imageamento por Ressonância Magnética/métodos , Próstata/patologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Humanos , Masculino , Pessoa de Meia-Idade , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Adulto Jovem
17.
Am J Sports Med ; 33(4): 561-7, 2005 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-15722279

RESUMO

BACKGROUND: The prevalence of jumper's knee across different sports has not been examined, and it is not known if there is a gender difference. Data from surgical case series indicate that there may be a high prevalence in sports with high speed and power demands. HYPOTHESIS: The aim of this study was to estimate the prevalence of jumper's knee in different sports among female and male athletes and to correlate the prevalence to the loading characteristics of the extensor mechanism in these sports. STUDY DESIGN: Cross-sectional study; Level of evidence, 4. METHODS: The authors examined approximately 50 Norwegian male and female athletes at the national elite level from each of the following 9 sports: athletics (male athletes: high jump, 100- and 200-m sprint), basketball (male athletes), ice hockey (male athletes), volleyball (male athletes), orienteering (male athletes), road cycling (male athletes), soccer (male and female athletes), team handball (male and female athletes), and wrestling (male athletes). The examination included an interview on individual characteristics (weight, age, height, and training background), a clinical examination, and self-recorded Victorian Institute of Sport Assessment score from 0 (worst) to 100 (best). RESULTS: The overall prevalence of current jumper's knee was 14.2% (87 of 613 athletes), with a significant difference between sports with different performance characteristics (range, 0%-45%). In addition, 51 athletes (8%) reported previous symptoms. The prevalence of current symptoms was highest in volleyball (44.6%+/-6.6%) and basketball (31.9%+/-6.8%), whereas there were no cases in cycling or orienteering. The prevalence of current jumper's knee was lower among women (5.6%+/-2.2%) compared with men (13.5%+/-3.0%; chi2 test, P=.042). The duration of symptoms among athletes with current jumper's knee (n=87) was 32+/-25 (standard deviation) months, with a Victorian Institute of Sport Assessment score of 64+/-19. CONCLUSION: The prevalence of jumper's knee is high in sports characterized by high demands on speed and power for the leg extensors. The symptoms are often serious, resulting in long-standing impairment of athletic performance.


Assuntos
Traumatismos em Atletas/epidemiologia , Traumatismos do Joelho/epidemiologia , Métodos Epidemiológicos , Feminino , Humanos , Masculino , Fatores Sexuais , Suporte de Carga
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