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1.
Sensors (Basel) ; 23(22)2023 Nov 14.
Artigo em Inglês | MEDLINE | ID: mdl-38005561

RESUMO

The maximum reflection at an open end of a standard rectangular waveguide is about -10 dB in its operating frequency range. It is often used without matching. For critical applications, it is desirable to further reduce the reflection coefficient. In this paper, a new technique is presented for the broadband impedance matching of an open-ended rectangular waveguide. The proposed technique employs three thin capacitive matching elements placed at proper intervals via a low-loss dielectric material. The capacitance of, and distance between, the matching elements are optimized for broadband impedance matching using a simulation tool. Based on the proposed technique, two design examples are presented for the matching of a WR75 waveguide radiator. A reflection coefficient of less than -16 dB and -20 dB has been achieved over a ratio bandwidth of 2.13:1 and 1.62:1, respectively.

2.
J Med Syst ; 42(10): 189, 2018 Sep 04.
Artigo em Inglês | MEDLINE | ID: mdl-30178422

RESUMO

False positive signals (FPSs) of continuous monitoring blood culture system (CMBCS) cause delayed reporting time and increased laboratory cost. This study aimed to analyze growth graphs digitally in order to identify specific patterns of FPSs and true positive signals (TPSs) and to find the method for improving positive predictive value (PPV) of FPS and TPS. 606 positive signal samples from the BACTEC FX (BD, USA) CMBCS with more than one hour of monitoring data after positive signal were selected, and were classified into FPS and TPS groups using the subculture results. The pattern of bacterial growth graph was analyzed in two steps: the signal stage recorded using the monitoring data until positive signal and the post-signal stage recorded using one additional hour of monitoring data gained after the positive signal. The growth graph before the positive signal consists of three periods; initial decline period, stable period, and steeping period. Signal stage analyzed initial decline period and stable period, and classified the graphs as standard, increasing, decreasing, irregular, or defective pattern, respectively. Then, all patterns were re-assigned as confirmed or suspicious pattern in the post-signal stage. Standard, increasing, and decreasing patterns with both initial decline period and stable period are typical patterns; irregular patterns lacking a smooth stable period and defective patterns without an initial decline period are false positive patterns. The false positive patterns have 77.2% of PPV for FPS. The confirmed patterns, showing a gradually increasing fluorescence level even after positive signal, have 97.0% of PPV for TPS.


Assuntos
Bactérias/isolamento & purificação , Hemocultura , Meios de Cultura , Reações Falso-Positivas , Monitorização Fisiológica , República da Coreia
3.
Appl Biochem Biotechnol ; 161(1-8): 502-10, 2010 May.
Artigo em Inglês | MEDLINE | ID: mdl-19937397

RESUMO

The microbial production of 1,3-propanediol (1,3-PD) from raw glycerol, a byproduct of biodiesel production, is economically and environmentally advantageous. Although direct use of raw glycerol without any pretreatment is desirable, previous studies have reported that this could cause inhibition of microbial growth. In this study, we investigated the effects of raw glycerol type, different microorganisms, and pretreatment of raw glycerol on the production of 1,3-PD. Raw glycerol from waste vegetable-oil-based biodiesel production generally caused more inhibition of 1,3-PD production and microbial growth compared to raw glycerol from soybean-oil-based biodiesel production. In addition, two raw glycerol types produced from two biodiesel manufacturers using waste vegetable oil exhibited different 1,3-PD production behavior, partially due to different amounts of methanol included in the raw glycerol from the two biodiesel manufacturers. Klebsiella strains were generally resistant to all types of raw glycerol while the growth of Clostridium strains was variably inhibited depending on the type of raw glycerol. The 1,3-PD production of the Clostridium strains using acid-pretreated raw glycerol was significantly enhanced compared to that with raw glycerol, demonstrating the feasibility of using raw glycerol for 1,3-PD production by various microorganisms.


Assuntos
Biocombustíveis , Clostridium/metabolismo , Glicerol/metabolismo , Klebsiella/metabolismo , Propilenoglicóis/metabolismo , Reatores Biológicos , Fermentação
4.
Biol Pharm Bull ; 29(2): 261-5, 2006 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-16462028

RESUMO

The purpose of this study was to characterize the putative anxiolytic-like effects of the aqueous extract of the rhizome of Gastrodia elata along with its phenolic constituents, 4-hydroxybenzyl alcohol (HA) and 4-hyroxybenzaldehyde (HD), using an elevated plus maze (EPM) in mice. The mice were administered either the aqueous G. elata extract orally or received an intraperitoneal injection of the phenolic constituents, 1 h before the behavioral evaluation in the EPM. A single treatment of the aqueous G. elata extract significantly increased the percentage of time spent and arm entries into the open arms of the EPM versus the saline controls. Among the phenolic constituents of G. elata, HA and HD significantly increased the percentage of time spent and arm entries into the open arms of the EPM versus saline controls (p<0.05). Moreover, there were no changes in the locomotor activity and myorelaxant effects in any group compared with the saline controls. In addition, the anxiolytic-like effects of G. elata extract were blocked by both WAY 100635 (0.3 mg/kg, i.p.), a 5-HT(1A) receptor antagonist, and flumazenil (10 mg/kg, i.p.), a GABA(A) receptor antagonist. The anxiolytic-like effects of HA were inhibited by WAY 100635 and the effects of HD were antagonized by flumazenil. These results indicate that G. elata is an effective anxiolytic agent, and suggests that the anxiolytic-like effects of G. elata via the serotonergic nervous system depends on HA and those effects of G. elata via the GABAergic nervous system depends on HD.


Assuntos
Ansiolíticos/farmacologia , Benzaldeídos/farmacologia , Álcoois Benzílicos/farmacologia , Gastrodia/química , Fenóis/química , Animais , Ansiolíticos/isolamento & purificação , Comportamento Animal/efeitos dos fármacos , Benzaldeídos/isolamento & purificação , Álcoois Benzílicos/isolamento & purificação , Flumazenil/farmacologia , Antagonistas GABAérgicos/farmacologia , Masculino , Aprendizagem em Labirinto/efeitos dos fármacos , Camundongos , Camundongos Endogâmicos ICR , Atividade Motora/efeitos dos fármacos , Piperazinas/farmacologia , Extratos Vegetais/isolamento & purificação , Extratos Vegetais/farmacologia , Piridinas/farmacologia , Rizoma/química , Antagonistas da Serotonina/farmacologia
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