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1.
J Med Signals Sens ; 12(2): 155-162, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35755979

RESUMO

Stress can lead to harmful conditions in the body, such as anxiety disorders and depression. One of the promising noninvasive methods, which has been widely used in detecting stress and emotion, is electrodermal activity (EDA). EDA has a tonic and phasic component called skin conductance level and skin conductance response (SCR). However, the components of the EDA cannot be directly extracted and need to be deconvolved to obtain it. The EDA signals were collected from 18 healthy subjects that underwent three sessions - Stroop test with increasing stress levels. The EDA signals were then deconvoluted by using continuous deconvolution analysis (CDA) and convex optimization approach to electrodermal activity (cvxEDA). Four features from the result of the deconvolution process were collected, namely sample average, standard deviation, first absolute difference, and normalized first absolute difference. Those features were used as the input of the classification process using the extreme learning machine (ELM). The output of classification was the stress level; mild, moderate, and severe. The visual of the phasic component using cvxEDA is more precise or smoother than the CDA's result. However, both methods could separate SCR from the original skin conductivity raw and indicate the small peaks from the SCR. The classification process results showed that both CDA and cvxEDA methods with 50 hidden layers in ELM had a high accuracy in classifying the stress level, which was 95.56% and 94.45%, respectively. This study developed a stress level classification method using ELM and the statistical features of SCR. The result showed that EDA could classify the stress level with over 94% accuracy. This system could help people monitor their mental health during overworking, leading to anxiety and depression because of untreated stress.

2.
J Med Signals Sens ; 10(2): 125-133, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32676449

RESUMO

BACKGROUND: Bioimpedance spectroscopy (BIS) is a device used to measure electrical impedance at frequencies from 0 Hz to 1 MHz. Many clinical diagnosis and fundamental researches, especially in the field of physiology and pathology, rely on this device. The device can be used to estimate human body composition, through the information of total body water, extracellular fluid and intracellular fluid, fat-free mass, and fat mass from its impedance. BIS analysis can provide physiological statuses such as ischemia, pulmonary edema, skin cancer, and intramuscular tumors. BIS is expected to be used even more widely, both for hospital or home-based use, particularly because BIS handy, compact, inexpensive, and less power-consuming with adequately accurate real-time. In previous research, the BIS design was based on the magnitude-ratio and phase-difference detection using the AD8302 gain-phase detector method which resulted in an operating range between 20 kHz and 1 MHz. However, the impedance was obtained from the logarithmic ratio magnitude which caused the device to have limited accuracy at frequencies <20 kHz. METHODS: In this research, we conduct design and development of a low-cost arduino-based electrical bioimpedance spectrometer. RESULTS: The low-cost bioimpedance spectrometry was successfully developed using AD9850 as the programmable function generator, OPA2134 as the OpAm of voltage-controlled current source, AD620A as the instrument amplifier and AD536A as the alternating current to direct current converter which could work accurately from 0 Hz to 100 kHz. CONCLUSION: The multi-frequency bioimpedance device developed in this research has the capability to safely measure the impedance of the human body due to its relatively stable electric current, which is equal to (0.370 ± 0.003) mA with frequencies ranging from 5 to 200 kHz and has an accuracy of over 90% in the frequency range of 10 Hz to 100 kHz.

3.
Dose Response ; 18(2): 1559325820921023, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32636718

RESUMO

In the shoes industry, benzene constitute as one of the source of chemical hazard especially used in the gluing section. This compound is metabolized by the liver, forming free radicals in the body which can ultimately reduce the concentration of glutathione and increased malondialdehyde causing DNA degeneration. The purpose of this study was to determine the relationship between benzene concentration, excess cancer risk (ECR), malondialdehyde, glutathione, and DNA degeneration among workers in shoes industry in Osowilangun, Surabaya. This is an observational study with a cross-sectional design. The number of research samples was 25 respondents. The average concentration of benzene in workers was above the threshold (10.31 ppm). There were 15 (60%) respondents with ECR >0.0001 who experienced DNA degeneration. There was no relationship between benzene concentration, malondialdehyde, glutathione, and DNA degeneration. However, there was a relationship between benzene ECR, malondialdehyde, glutathione, and DNA degeneration in the shoe industry workers in Osowilangun.

4.
Sensors (Basel) ; 20(7)2020 Mar 30.
Artigo em Inglês | MEDLINE | ID: mdl-32235454

RESUMO

This research offers a method for separating the components of tissue impedance, namely resistance and capacitive reactance. Two objects that have similar impedance or low contrast can be improved through separating the real and imaginary images. This method requires an Electrical Impedance Tomography (EIT) device. EIT can obtain potential data and the phase angle between the current and the potential measured. In the future, the device is very suitable for imaging organs in the thorax and abdomen that have the same impedance but different resistance and capacitive reactance. This device consists of programmable generators, Voltage Controlled Current Source (VCCS), mulptiplexer-demultiplexer potential meters, and phase meters. Data collecting was done by employing neighboring, while reconstruction was used the linear back-projection method from two different data frequencies, namely 10 kHz and 100 kHz. Phantom used in this experiment consists of distillated water and a carrot as an anomaly. Potential and phase data from the device is reconstructed to produce impedance, real, and imaginary images. Image analysis is performed by comparing the three images to the phantom. The experimental results show that the device is reliable.


Assuntos
Impedância Elétrica , Processamento de Imagem Assistida por Computador/métodos , Tórax/diagnóstico por imagem , Tomografia/métodos , Algoritmos , Humanos , Imagens de Fantasmas
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