Thiamethoxam-induced hematological, biochemical, and genetic alterations and the ameliorated effect of Moringa oleifera in male mice.

Thiamethoxam (TMX) exerts pronounced insecticidal effects against a wide variety of economically imperative pests. However, the administration of TMX in experimental animals induced notable adverse effects on the function of various organs. The purpose of this study was to assess TMX induced hematological, biochemical, and genetic alterations and the potential ameliorative effects on them of Moringa oleifera leaf extract (MLE) in male mice Animals were orally administered TMX (≈1/10 LD50) daily either alone or with MLE (200 mg/kg b.w.) for 28 successive days. Blood was collected to evaluate the hematological profile and serum levels of Aspartate Aminotransferase (AST), Alanine aminotransferase (ALT), alkaline phosphatase (ALP), albumin, creatinine, uric acid, and urea. Liver and kidney cells were used to assess the Malondialdehyde (MDA) content and antioxidant enzymes. DNA integrity was estimated also in the liver and kidney using comet and colorimetric diphenylamine assays. Results revealed that TMX exhibited significant changes in the hematological profile and liver and kidney functions. Besides, TMX significantly raised the MDA content and DNA damage in both two of these organs. In contrast, TMX reduced the antioxidant activities in the cells of both liver and kidney. Meanwhile, Moringa extract combined with TMX significantly attenuated the deleterious findings of TMX. Specifically, it improved the TMX-induced hematological changes, liver and kidney function alterations, oxidative stress, and DNA damage rate. It can be concluded that TMX had adverse effects on different cells of male mice, but MLE successfully ameliorated TMX's hematological and hepatorenal toxicity.

Metal Ion Removal from Wastewaters by Sorption on Activated Carbon, Cement Kiln Dust, and Sawdust.

This study assessed the efficiency of activated carbon, cement kiln dust (CKD), and sawdust for the removal of cadmium (Cd), copper (Cu), lead (Pb), and zinc (Zn) from aqueous solutions under mono-metal and competitive sorption systems and the removal of Cd, Cu, and Zn from different industrial wastewaters. Batch equilibrium experiments were conducted in a mono-metal and competitive sorption system. The efficiency of the sorbents in the removal of Cd, Cu, and Zn from industrial wastewaters was also investigated. Cement kiln dust expressed the highest affinity for the metals followed by activated carbon and sawdust. Competition among the metals changed their distribution coefficient (Kd) with the sorbents. Sorption of Pb and Cu was higher than Cd and Zn. The average metal removal from the wastewaters varied from 74, 61, and 60% for Cd, Cu, and Zn, respectively, to nearly 100%. The efficiencies of CKD and activated carbon in removing metals were higher than sawdust, suggesting their potential as low-cost sorbents for the removal of toxic metals from wastewaters.

Heavy metals removal from aqueous solutions and wastewaters by using various byproducts.

Water contamination with heavy metals (HM) represents a potential threat to humans, animals and plants, and thus removal of these metals from contaminated waters has received increasing attention. The present study aimed to assess the efficiency of some low cost sorbents i.e., chitosan (CH), egg shell (ES), humate potassium (HK), and sugar beet factory lime (SBFL) for removal of cadmium (Cd), copper (Cu), lead (Pb) and zinc (Zn) from wastewaters. For this purpose batch equilibrium experiments were conducted with aqueous solutions containing various concentrations of the metals and sorbents in a mono-metal and competitive sorption system. Sorption isotherms were developed, and sorption parameters were determined. The potential applicability of the tested sorbents in the removal of Cd, Cu, and Zn from contaminated wastewaters was also investigated by equilibrating different sorbents and water ratios. Chitosan expressed the highest affinity for the metals followed by SBFL, ES, and HK. Nearly 100% of the metals were removed from aqueous solutions with the lowest initial metal concentrations by the sorbents especially CH and SBFL. However, the sorption efficiency decreased as the initial metal concentrations increased. Competition among the four metals changed significantly their distribution coefficient (Kd) values with the sorbents. The selectivity sequence of the metals was: Pb > Cu > Zn > Cd. The metal removal from the wastewaters varied from 72, 69, and 60 to nearly 100% for Cd, Cu and Zn, respectively. The efficiency of the studied byproducts in removing metals from the wastewaters differed based on the source of contamination and metal concentrations. Cadmium removal percentages by HK and CH were higher than SBFL and ES. The HK and CH exhibited the highest removal percentage of Cu from water with high concentrations. The SBFL and ES revealed the highest removal percentage of Zn from water with high concentrations. The results, demonstrate a high potential of CH, SBFL, HK, and ES for the remediation of HM contaminated wastewaters.