Multi-path decoder U-Net: A weakly trained real-time segmentation network for object detection and localization in ultrasound scans.

Detecting and localizing an anatomical structure of interest within the field of view of an ultrasound scan is an essential step in many diagnostic and therapeutic procedures. However, ultrasound scans suffer from high levels of variabilities across sonographers and patients, making it challenging for sonographers to accurately identify and locate these structures without extensive experience. Segmentation-based convolutional neural networks (CNNs) have been proposed as a solution to assist sonographers in this task. Despite their accuracy, these networks require pixel-wise annotations for training; an expensive and labor-intensive operation that requires the expertise of an experienced practitioner to identify the precise outline of the structures of interest. This complicates, delays, and increases the cost of network training and deployment. To address this problem, we propose a multi-path decoder U-Net architecture that is trained on bounding box segmentation maps; not requiring pixel-wise annotations. We show that the network can be trained on small training sets, which is the case in medical imaging datasets; reducing the cost and time needed for deployment and use in clinical settings. The multi-path decoder design allows for better training of deeper layers and earlier attention to the target anatomical structures of interest. This architecture offers up to a 7% relative improvement compared to the U-Net architecture in localization and detection performance, with an increase of only 0.75% in the number of parameters. Its performance is on par with, or slightly better than, the more computationally expensive U-Net++, which has 20% more parameters; making the proposed architecture a more computationally efficient alternative for real-time object detection and localization in ultrasound scans.

A CNN Segmentation-Based Approach to Object Detection and Tracking in Ultrasound Scans with Application to the Vagus Nerve Detection.

Ultrasound scanning is essential in several medical diagnostic and therapeutic applications. It is used to visualize and analyze anatomical features and structures that influence treatment plans. However, it is both labor intensive, and its effectiveness is operator dependent. Real-time accurate and robust automatic detection and tracking of anatomical structures while scanning would significantly impact diagnostic and therapeutic procedures to be consistent and efficient. In this paper, we propose a deep learning framework to automatically detect and track a specific anatomical target structure in ultrasound scans. Our framework is designed to be accurate and robust across subjects and imaging devices, to operate in real-time, and to not require a large training set. It maintains a localization precision and recall higher than 90% when trained on training sets that are as small as 20% in size of the original training set. The framework backbone is a weakly trained segmentation neural network based on U-Net. We tested the framework on two different ultrasound datasets with the aim to detect and track the Vagus nerve, where it outperformed current state-of-the-art real-time object detection networks.Clinical Relevance-The proposed approach provides an accurate method to detect and localize target anatomical structures in real-time, assisting sonographers during ultrasound scanning sessions by reducing diagnostic and detection errors, and expediting the duration of scanning sessions.