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Cutan Ocul Toxicol ; : 1-11, 2024 Aug 18.
Artigo em Inglês | MEDLINE | ID: mdl-39155622

RESUMO

Environmental contamination is a significant global health issue, with cosmetics and pharmaceuticals being major polluters. High concentrations of heavy metals, such as Hg, have been found to have toxic effects and may pose a threat to human health. This study aimed to determine the concentration of mercury (Hg) in lipsticks available in the Saudi Arabia market. In this study, 12 lipstick samples from three colours were analysed using inductively coupled plasmaoptical emission spectrometry (ICP-OES) to measure the content of Hg. The concentration range of Hg was 0.004-0.296 ppm. Moreover, the systemic exposure dosage of mercury in the lipstick samples examined in this study ranged from 5.01x10-8 to 1.43x10-6 µg/kg bw/day, while the range of the margin of safety was from 7.3 x 109 to 2.2 x 108.The Hg concentration in all analysed samples was less than 0.50 and 1 ppm, which indicated that the Hg level was within acceptable limits according to Saudi Standards, Metrology and Quality Organization (SASO) and the United States Food and Drug Administration (US FDA), respectively.On the other hand, the calculated margin of safety values for mercury exceeded the safe standard established by the WHO. The results derived from using hazard quotient (HQ) indices depict the potential carcinogenic health risk posed to consumers who employ red-coloured lipsticks.

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