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1.
Cureus ; 16(1): e53298, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38435913

RESUMO

BACKGROUND: Unnecessary prescription of antibiotics for patients with upper respiratory tract infections (URTIs) carries the potential risk to the development of bacterial resistance. OBJECTIVE: This study aimed to investigate the behavior of primary healthcare (PHC) physicians toward an antibiotic prescription for URTI, Al-Madinah City, Saudi Arabia in 2021. METHODS: A cross-sectional study was conducted at PHC centers in Al-Madinah City, Saudi Arabia. The study invited all physicians in the randomly selected 28 PHC centers to participate in the study. A master sheet adopted from a researcher done in the Asir region of Saudi Arabia about the pattern of prescription for URTI was used and included data about socio-demographic characteristics and data about presenting symptoms and signs of URTIs, the clinical diagnosis, type of medication prescribed, and duration of treatment also, included data about the factors that press physicians to prescribe antibiotics and their response. The questionnaire was filled out and returned back by 140 physicians. The collected data were analyzed and tabulated using appropriate statistical tests. RESULTS: The mean age of the studied physicians was 34.4 ± 7.6 years (25-59 years). General practitioners and specialists were 66.4% and 33.6%, respectively. The prevalence of antibiotic prescriptions was 44.3%. The most prescribed antibiotics were amoxicillin (58.6%) and Augmentin (28.6%). Congested tonsils (87.1%), ear discharge (84.2%), and cervical lymphadenopathy (89.3%) were the most clinical factors that affected physicians' decisions to prescribe antibiotics for URTI. The non-clinical factors affecting physicians' decisions include patient request (52.8%) and press (28.5%), with no statistically significant difference detected between general practitioners and specialists. CONCLUSION: The study findings indicate the need to develop intervention programs targeting physicians as well as the general population to decrease inappropriate antibiotic prescriptions in primary care centers.

2.
Cureus ; 16(1): e51865, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38327941

RESUMO

Otitis media, a common inflammation of the middle ear, frequently complicates upper respiratory infections. Gradenigo's syndrome, a rare complication, manifests as suppurative otitis media, abducens nerve palsy, and severe trigeminal nerve pain. Prompt recognition is vital because of the proximity of the infection to critical neurovascular structures. We present the case of a 38-year-old female who presented with facial pain, otalgia, and diplopia following an upper respiratory infection. Examination revealed facial weakness and abducens nerve palsy. Laboratory results showed elevated inflammatory markers. Imaging confirmed middle ear involvement. Antibiotics were initiated, and myringotomy was performed, resulting in a successful outcome. This case report contributes to understanding Gradenigo's syndrome's clinical nuances, emphasizing the necessity of a structured diagnostic and therapeutic approach. Ongoing research is crucial for refining diagnostic criteria, optimizing treatment, and enhancing pathophysiological understanding. Increased medical education is imperative to ensure early detection and improved patient outcomes.

3.
Cureus ; 16(1): e51942, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38333486

RESUMO

The Bacillus Calmette-Guérin (BCG) vaccine, a cornerstone in global immunization programs for tuberculosis prevention, has generally proven to be safe and effective. However, rare complications, including localized abscess formation, have been reported. This case report highlights a two-year-old male who developed a painless swelling on the left chest wall, noticed six weeks post-BCG vaccination. Physical and imaging evaluations confirmed a cold abscess. Laboratory tests ruled out alternative diagnoses. Antitubercular therapy led to a favorable response, avoiding surgical intervention. Follow-up revealed complete resolution, showcasing successful management of this rare BCG-related complication in a pediatric patient. The success of antimycobacterial therapy supports a tailored and conservative approach, raising questions about the necessity of surgical intervention. The presented case sheds light on the complex interplay between BCG vaccination, host response, and rare complications, providing valuable insights for further research. Vigilance, robust surveillance, and collaborative efforts are essential to unravel vaccine-related adverse events. This case contributes to a deeper understanding of rare BCG-related complications, guiding clinical practice, and advancing the knowledge base.

4.
Cureus ; 16(1): e52302, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38357058

RESUMO

Trigeminal schwannomas, rare tumors originating from Schwann cells of the trigeminal nerve, present unique diagnostic challenges due to their infrequent occurrence. The clinical manifestation of facial numbness and tingling necessitates a comprehensive approach for accurate diagnosis and optimal management. We present the case of a 45-year-old female who presented with a six-month history of progressive facial numbness localized to the left maxillary and mandibular regions. Intermittent sharp, shooting pain exacerbated by chewing and cold stimuli was reported. Physical examination revealed sensory deficits in left trigeminal nerve distribution. Magnetic resonance imaging confirmed a well-circumscribed, enhancing lesion along the left trigeminal nerve. Surgical excision of the tumor confirmed the diagnosis of schwannoma. This case underscores the significance of a detailed clinical history, advanced imaging, and collaboration between neurologists and neurosurgeons in achieving an accurate diagnosis and favorable outcome for trigeminal schwannomas. The successful surgical intervention, coupled with histopathological confirmation, contributes to the understanding of these rare tumors.

5.
Cureus ; 16(1): e52963, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38406127

RESUMO

Cubonavicular coalition is a rare congenital anomaly involving fibrous or osseous fusion between the cuboid and navicular bones. This case report presents a comprehensive analysis of a 10-year-old female patient with cubonavicular coalition, detailing the diagnostic challenges and tailored therapeutic interventions. The patient presented with persistent left foot pain and restricted range of motion. Clinical examination, radiographic studies, and magnetic resonance imaging confirmed cubonavicular coalition. Laboratory investigations ruled out systemic inflammatory processes. A multidisciplinary approach was adopted, initially employing nonsteroidal anti-inflammatory drugs and physical therapy. Surgical resection of the coalition was performed due to persistent symptoms, leading to successful outcomes. This case report contributes valuable insights into the clinical presentation, diagnosis, and management of cubonavicular coalition in pediatric patients. The successful outcome underscores the importance of a comprehensive and individualized approach, providing a basis for informed decision-making in similar cases. Continued research is essential to refine therapeutic algorithms and enhance understanding of rare musculoskeletal anomalies.

6.
Cureus ; 16(1): e51506, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38304654

RESUMO

Cavernomas, also known as cavernous angiomas or cavernous malformations, are rare vascular lesions characterized by abnormal clusters of dilated capillaries without intervening brain tissue. While often asymptomatic, they can manifest with neurological symptoms such as headaches, seizures, and focal deficits. We present a case of a 45-year-old male who presented with persistent headaches and visual hallucinations. Thorough clinical assessment revealed intermittent throbbing headaches localized to the left occipital region, accompanied by brief episodes of vivid visual hallucinations. Extensive work-up, including laboratory tests and neuroimaging, identified a subependymal cavernoma in the left occipital lobe. A surgical excision was performed, resulting in sustained relief from headaches and the absence of visual hallucinations during follow-up examinations. This case contributes to the understanding of cavernomas by detailing the clinical presentation, diagnostic process, and successful surgical intervention for a subependymal cavernoma in the left occipital lobe. The resolution of symptoms postoperatively underscores the importance of individualized treatment approaches, considering factors such as lesion location, patient age, and associated risks. The case highlights the evolving knowledge in cavernoma management and emphasizes the need for tailored therapeutic decisions in addressing neurovascular disorders.

7.
Cureus ; 16(1): e51736, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38318598

RESUMO

Disseminated superficial porokeratosis is a rare dermatological disorder characterized by annular keratotic lesions, presenting diagnostic challenges due to its variable clinical manifestations. The pathogenesis involves genetic predisposition and environmental factors, with mutations in the mevalonate pathway implicated. Despite its benign nature, this condition significantly impacts patients' quality of life, necessitating accurate diagnosis and effective therapeutic strategies. We present the case of a 45-year-old female with a three-year history of annular plaques on sun-exposed areas progressing to involve multiple body regions. The characteristic histopathological finding of coronoid lamellae confirmed the diagnosis of disseminated superficial porokeratosis. Treatment involved a multimodal approach, including topical corticosteroids, calcineurin inhibitors, and systemic retinoids, resulting in satisfactory clinical outcomes. Long-term follow-up emphasized the need for ongoing disease monitoring and patient education regarding sun protection. The presented case underscores the importance of recognizing characteristic histopathological features for accurate diagnosis and highlights the significance of long-term follow-up, disease monitoring, and patient education to optimize outcomes and enhance overall quality of life.

8.
Cureus ; 15(11): e48158, 2023 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-38046761

RESUMO

Esophageal leiomyomatosis, an uncommon benign condition marked by the proliferation of smooth muscle cells within the esophageal wall, frequently presents diagnostic challenges due to its rarity and diverse clinical manifestations. In this case report, we document the clinical journey of a 28-year-old female who presented with a two-year history of progressive dysphagia. Upon physical examination and endoscopy, a submucosal mass in the lower esophagus was identified, prompting further imaging and subsequent biopsy, which confirmed the diagnosis of leiomyomatosis. A multidisciplinary team recommended surgical intervention, leading to a minimally invasive laparoscopic resection of the esophageal leiomyomas. Postoperatively, the patient experienced a substantial improvement in her dysphagia and was discharged in stable condition. This case not only underscores the importance of a multidisciplinary approach in achieving an accurate diagnosis but also highlights the successful application of minimally invasive surgical techniques for alleviating symptoms in esophageal leiomyomatosis patients. The rarity and varied clinical presentation of this condition emphasize the need for individualized and tailored management strategies.

9.
Cureus ; 15(9): e45497, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-37859913

RESUMO

Migraine, a widespread and incapacitating neurological disorder, affects numerous individuals worldwide, causing severe headaches and impairing their quality of life. The interplay of genetic, environmental, and neurovascular factors underlies the pathophysiology of migraine. This report highlights the case of a 25-year-old woman with recurrent, severe headaches, predominantly in the right frontal and temporal regions. She was diagnosed with migraine with aura, a diagnosis supported by her family history. No previous history of seizures was reported. A comprehensive work-up, including neuroimaging, revealed left internal carotid artery hypoplasia with compensatory collateral circulation. The coexistence of severe migraines and left internal carotid artery hypoplasia underscores the complex interrelationship between cerebrovascular anomalies and neurological symptoms. The rarity of this vascular variation emphasizes the need for attentive clinical evaluation and consideration of anatomical deviations in migraine patients. As medical knowledge progresses, further research is essential to unravel the mechanisms connecting vascular anomalies and neurological disorders, ultimately leading to personalized interventions for improved patient outcomes.

10.
Cureus ; 15(9): e46113, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-37900502

RESUMO

Splenic cysts in the pediatric population are rare but can present with a range of clinical manifestations. Acute abdominal pain, although uncommon, is a significant presentation that requires prompt evaluation and management. We present the case of an 11-year-old female who presented to the emergency department with severe left upper quadrant abdominal pain of 24 hours' duration. Physical examination revealed tenderness and guarding in the left upper quadrant with a palpable, firm mass. Elevated serum amylase and lipase levels initially raised suspicion of a pancreatic etiology, but further investigations confirmed the presence of a large cystic lesion in the spleen. The patient underwent laparoscopic splenectomy, and the resected specimen confirmed a benign splenic cyst. Postoperatively, she recovered uneventfully and was discharged with appropriate follow-up plans. This case report underscores the importance of early recognition and prompt surgical intervention in managing splenic cysts in pediatric patients. The diverse etiologies and pathophysiological mechanisms of splenic cysts necessitate a comprehensive diagnostic approach.

11.
Cureus ; 15(9): e44902, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-37814772

RESUMO

A carotid-cavernous fistula is a rare vascular anomaly involving abnormal communication between the carotid artery and the cavernous sinus. This condition leads to the shunting of arterial blood directly into the venous system, causing diverse clinical manifestations. The classification includes direct and indirect fistulas, with endovascular techniques emerging as a preferred treatment option. In this report, we present the case of a 58-year-old male who presented with progressive right-sided proptosis, headache, and visual disturbances. He exhibited right abducens nerve palsy, reduced visual acuity, and a dilated superior ophthalmic vein on imaging. A multidisciplinary team confirmed the diagnosis of a carotid-cavernous fistula and chose to pursue endovascular embolization. Catheter angiography revealed the fistula and balloon-assisted occlusion restored normal arterial flow. The patient's symptoms improved, and follow-up showed complete resolution of proptosis and enhanced visual acuity. Successful endovascular embolization underscores the significance of a multidisciplinary approach and showcases the positive outcomes achievable when diverse specialties converge for patient well-being.

12.
Cureus ; 15(8): e43108, 2023 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-37692598

RESUMO

Ovarian cystadenomas are rare neoplastic tumors arising from the ovarian surface epithelium. While commonly observed in adult women, their occurrence in adolescents is exceedingly uncommon. The management of large ovarian cystadenomas in this age group poses unique challenges due to acute presentations and potential complications. We present the case of a 16-year-old girl who presented with sudden, severe abdominal pain and distension. Imaging revealed a 15 cm complex cystic mass originating from the right ovary, consistent with a cystadenoma. Urgent surgical intervention led to the right salpingo-oophorectomy, confirming the benign nature of the tumor. This report highlights the importance of a comprehensive approach to diagnosing and managing rare ovarian neoplasms in adolescents. Timely recognition, appropriate imaging, histopathological evaluation, and surgical intervention are crucial for optimal outcomes and reducing potential complications.

13.
Cureus ; 15(7): e42525, 2023 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-37637667

RESUMO

May-Thurner syndrome, also known as iliocaval compression syndrome, is a rare vascular condition that involves compression of the left common iliac vein by the right common iliac artery. This compression can lead to venous stasis and increase the risk of deep vein thrombosis in the left lower extremity. Treatment options range from conservative measures to endovascular procedures such as venous stenting. Here, we present the case of a 45-year-old female with a history of recurrent deep vein thrombosis in her left leg, who arrived at the emergency department with swelling, pain, and tenderness. She was on warfarin therapy for deep vein thrombosis management. Physical examination and laboratory investigations supported the diagnosis of acute deep vein thrombosis. Further investigations revealed May-Thurner syndrome, with the left common iliac vein being compressed by the right common iliac artery, leading to extensive thrombosis in the left lower extremity. Endovascular stenting was performed to relieve the obstruction and restore venous blood flow. The patient's symptoms improved after the stenting procedure, and she remained asymptomatic during follow-up with continued anticoagulation therapy. Awareness of May-Thurner syndrome is crucial, especially in patients with recurrent deep venous thrombosis and anatomical risk factors. Successful management requires a multidisciplinary approach involving anticoagulation therapy and endovascular stenting.

14.
Cureus ; 15(7): e42224, 2023 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-37605682

RESUMO

Carotid body tumors are rare neuroendocrine tumors originating from paraganglionic cells in the carotid body. Although these tumors are typically slow-growing and benign, their location and vascularity present unique challenges in management. Here, we present a case study of a 58-year-old male who presented with a painless, gradually enlarging neck mass over a six-month period. Physical examination revealed a non-tender, pulsatile mass measuring approximately 3 cm in the left carotid triangle. Imaging studies, including ultrasound and contrast-enhanced computed tomography, confirmed the presence of a well-defined, hypoechoic mass at the left carotid bifurcation, displacing adjacent vessels. A multidisciplinary team planned surgical resection, guided by imaging, resulting in the successful removal of the tumor. Histopathological examination confirmed the diagnosis of a carotid body tumor. This case report underscores the significance of accurate diagnosis, a multidisciplinary approach, and advanced imaging techniques in managing carotid body tumors. Surgical resection, guided by imaging, aims to achieve complete excision while preserving vital structures. Long-term follow-up is crucial to detect potential recurrence or progression early.

15.
Cureus ; 15(5): e38589, 2023 May.
Artigo em Inglês | MEDLINE | ID: mdl-37284391

RESUMO

Polysplenia syndrome is a rare congenital anomaly characterized by multiple spleens and associated organ anomalies, which can present with serious complications such as splenic infarction. Diagnosis and management of the disorder can be challenging due to the presence of associated anomalies and the condition is often diagnosed incidentally. We report a case of a six-year-old girl with no significant medical history who presented to the emergency department with fever, abdominal pain, and vomiting. Physical examination and laboratory investigations showed leukocytosis, anemia, and elevated levels of C-reactive protein. A computed tomography scan revealed splenic infarction with polysplenia syndrome. The patient received intravenous antibiotics and pain management and was closely monitored for complications such as sepsis. Early diagnosis and appropriate management are essential to prevent complications, and close monitoring and follow-up are necessary for long-term management.

16.
Cureus ; 15(3): e36875, 2023 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-37123689

RESUMO

Angiolipoma is a benign soft tissue tumor composed of mature adipocytes and small capillaries. Although it can occur in any part of the body, it is rare in the oral cavity, especially in the lips. We report the case of a 47-year-old male who presented with a painless, slow-growing mass on the right lower lip that had gradually increased in size over several months. The initial diagnosis included lipoma, mucocele, and hemangioma. The mass was surgically excised, and the histological examination confirmed the diagnosis of angiolipoma. Angiolipomas involving the lips are rare and can be easily misdiagnosed. Therefore, clinical suspicion, along with appropriate imaging and histological examination, is essential for an accurate diagnosis and appropriate management. The patient had a smooth recovery after surgery and showed no recurrence of the condition during the one-year follow-up examination.

17.
Cureus ; 15(3): e36846, 2023 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-37123700

RESUMO

Trigeminal neuralgia is a rare and debilitating condition characterized by severe facial pain, often caused by the compression or irritation of the trigeminal nerve. Although trigeminal neuralgia caused by petrous bone lesions is uncommon, it can significantly impact a patient's quality of life. In this case report, we describe a 40-year-old female with a five-year history of severe facial pain diagnosed as trigeminal neuralgia. Imaging revealed an aneurysmal bone cyst in the petrous part of the left temporal bone, located near the trigeminal nerve's root entry zone. The patient underwent a successful left retrosigmoid craniotomy with the resection of the lesion, resulting in a significant improvement in her symptoms. At the six-month follow-up, the patient reported no recurrence of her symptoms and a considerable improvement in her quality of life. Although trigeminal neuralgia caused by an aneurysmal bone cyst in the left temporal bone is rare, surgery is the most effective treatment. Long-term outcomes are generally favorable with close follow-up. This case report highlights the importance of early diagnosis and timely surgical intervention in the management of this debilitating condition.

18.
Cureus ; 15(4): e37054, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-37153313

RESUMO

Artery of Percheron infarction is a serious but rare condition that can result in acute bilateral thalamic infarction and a wide range of neurological symptoms. It occurs due to occlusion of the single arterial branch that supplies the medial thalamus and rostral midbrain bilaterally. In this case report, we describe a 58-year-old female with a history of hypertension and hyperlipidemia who presented with sudden confusion, speech difficulties, and right-sided weakness. An initial CT scan showed ill-defined hypodensity in the left internal capsule, which, when combined with the clinical features, suggested acute ischemic stroke. The patient received an IV tissue plasminogen activator within the recommended time window. Several days later, repeated imaging showed bilateral thalamic hypodensity consistent with subacute infarction in the territory of the artery of Percheron. The patient was subsequently discharged to a rehabilitation facility for further recovery and rehabilitation with residual mild hemiparesis. It is important for healthcare providers to maintain a high index of suspicion for the artery of Percheron infarction and be aware of its potential to cause acute bilateral thalamic infarction and a variety of neurological symptoms.

19.
Cureus ; 15(4): e37620, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-37197107

RESUMO

The abdominal aortic aneurysm (AAA) is a vascular condition that commonly affects individuals over the age of 65, leading to complications such as rupture, thrombosis, and embolization that can result in significant morbidity and mortality. Aorto-enteric fistula (AEF), a rare but life-threatening complication of abdominal aortic aneurysms, occurs when there is communication between the aneurysm and adjacent bowel loops. A 63-year-old man presented to the emergency department (ED) with severe abdominal pain, nausea, vomiting, and dark, tarry stools. Prior to his current presentation, the patient sought medical care from several primary care centers for vague abdominal pain that was diagnosed as dyspepsia, and he was prescribed omeprazole. During the current presentation, the patient had hemodynamic instability and a diffusely tender abdomen. Subsequently, a computed tomography (CT) scan revealed an abdominal aortic aneurysm with AEF. Although the patient underwent exploratory laparotomy, he suffered cardiac arrest and ultimately died in the operating room. This case underscores the importance of early recognition and management of AEF, which is crucial for improving patient outcomes.

20.
Cureus ; 15(4): e38106, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-37252494

RESUMO

Aortocaval fistula is a rare but serious complication of an abdominal aortic aneurysm characterized by communication between the dilated abdominal aorta and inferior vena cava. Prompt diagnosis and treatment are essential to reduce the mortality rate. A 66-year-old man with a history of poorly controlled hypertension, diabetes mellitus, and dyslipidemia presented to the emergency department with sudden, severe lower back pain. Laboratory investigations showed a rapid drop in hemoglobin levels and increased lactate levels. A CT scan revealed an aortocaval fistula resulting from a rupture of the abdominal aorta. The patient underwent emergency surgery, but a cardiac arrest occurred during the procedure, and he could not be resuscitated. Despite advances in imaging and surgical techniques, the mortality rate of aortocaval fistula remains high. It is crucial for clinicians to maintain a high level of suspicion for aortocaval fistula in patients with an abdominal aortic aneurysm who present with a sudden onset of abdominal and back pain and to initiate appropriate resuscitative measures and an urgent surgical consultation.

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