RESUMO
Cutaneous adenosquamous carcinoma is a mixed, squamous and glandular, rare malignant tumor of the skin characterized by a mixed, squamous, and glandular differentiation. Few cases of this tumor have been so far reported, and even fewer have been thoroughly studied by immunohistochemistry. We report here an exceptional case of cutaneous adenosquamous carcinoma which showed immunohistochemically features of intestinal differentiation, namely because of the expression of keratin 20 and CDX2, a marker of gastrointestinal tumors.
Assuntos
Carcinoma Adenoescamoso/patologia , Neoplasias de Cabeça e Pescoço/patologia , Couro Cabeludo/patologia , Neoplasias Cutâneas/patologia , Idoso de 80 Anos ou mais , Biomarcadores Tumorais/análise , Fator de Transcrição CDX2/análise , Carcinoma Adenoescamoso/química , Carcinoma Adenoescamoso/cirurgia , Neoplasias de Cabeça e Pescoço/química , Neoplasias de Cabeça e Pescoço/cirurgia , Humanos , Imuno-Histoquímica , Queratina-20/análise , Masculino , Fenótipo , Couro Cabeludo/química , Couro Cabeludo/cirurgia , Neoplasias Cutâneas/química , Neoplasias Cutâneas/cirurgiaRESUMO
Porokeratotic eccrine ostial and dermal duct nevus (PEODDN) is a rare dermatosis initially described as 'comedo nevus' and renamed 'PEODDN'; it has also been referred to as linear eccrine nevus with comedones, porokeratotic eccrine ostial and hair follicle nevus, and porokeratotic adnexal ostial nevus. PEODDN is usually present at birth or develops early in life. Rarely, PEODDN can develop in adults. The treatment of this puzzling condition is not standardized. We report herein a new case of adultonset PEODDN with dermatoscopic images. Our patient responded favorably to topical tazarotene.