Preparation and Characterization of a Renewable Starch-g-(MA-DETA) Copolymer and Its Adjustment for Dye Removal Applications.

Maleic anhydride-diethylenetriamine grafted on starch (st-g-(MA-DETA)) was synthesized through graft copolymerization, and the different parameters (copolymerization temperature, reaction time, concentration of initiator and monomer concentration) affecting starch graft percentage were studied to achieve the maximum grafting percentage. The maximum grafting percentage was found to be 29.17%. The starch and grafted starch copolymer were characterized using XRD, FTIR, SEM, EDS, NMR, and TGA analytical techniques to describe copolymerization. The crystallinity of starch and grafted starch was studied by XRD, confirming that grafted starch has a semicrystalline nature and indicating that the grafting reaction took place typically in the amorphous region of starch. NMR and IR spectroscopic techniques confirmed the successful synthesis of the st-g-(MA-DETA) copolymer. A TGA study revealed that grafting affects the thermal stability of starch. An SEM analysis showed the microparticles are distributed unevenly. Modified starch with the highest grafting ratio was then applied to celestine dye removal from water using different parameters. The experimental results indicated that St-g-(MA-DETA) has excellent dye removal properties in comparison to native starch.

Hemoglobin level is associated with severe stroke among stroke patients in Saudi Arabia.

OBJECTIVES: The purpose of this study was to examine the association between abnormal hemoglobin (Hb) level and stroke severity (as assessed by the National Institutes of Health Stroke Scale [NIHSS]). The study further aimed to describe the demographic and clinical characteristics of stroke patients in the middle region of Saudi Arabia. METHODOLOGY: We performed a retrospective review of all medical records of the stroke patients who were treated at a major hospital in Qassim province between 2016 and 2018. Reviewed data (n = 400) included demographics, Hb level on admission, type of stroke (ischemic vs. hemorrhagic), stroke risk factors, and NIHSS scores. Analysis of variance (ANOVA) test was used to assess the univariate association between NIHSS and Hb level. Regression statistics were utilized to examine the effect of abnormal Hb level on NIHSS scores while controlling for the other study variables. Data were analyzed using Statistical Package for the Social Sciences. RESULTS: Sixty-nine percent of the patients were men. More young women than men (≤39 years) had a stroke. Ischemic stroke is considerably more common than hemorrhagic stroke (a ratio of 12.7:1). ANOVA test showed that the mean score of NIHSS was significantly lower among patients with a normal Hb level. Regression showed that NIHSS scores were significantly associated with abnormal Hb level, in terms of low and high level. CONCLUSIONS: This study demonstrated further evidence of the association between abnormal Hb level NIHSS. Thus, our results emphasize the predictive importance of Hb level on identifying individuals who might be at higher risk of worse neurological outcomes after stroke. Physicians need to be cognizant of the negative effect of abnormal Hb level on the outcomes of stroke patients.

Pharmacovigilance Perception and Knowledge Among Pharmacists and Interns in Saudi Arabia.

AIM: The aim of this study was to determine and compare the level of knowledge and perception of ADRs reporting and pharmacovigilance among interns and hospital pharmacists in different health-care settings in Saudi Arabia. METHODS: A cross-sectional study was conducted among pharmacists and pharmacy interns in different hospitals in Saudi Arabia. A total of 315 participants completed the self-administered and validated questionnaire during the period from August 2018 to March 2019. RESULTS: There was poor perception and knowledge of pharmacovigilance and ADRs reporting among pharmacists as well as intern pharmacists. However, pharmacists had better knowledge score compared to interns (P=0.043). Most of the respondents believed that ADRs reporting is important. The majority of both interns and pharmacists stated that they did not receive adequate education about pharmacovigilance during their undergraduate or internship program. CONCLUSION: There is a gap in knowledge and perception about pharmacovigilance among practicing pharmacists and new pharmacy graduates. Drug safety fundamentals and policies should be taught to undergraduate pharmacy students in Saudi Arabia.

Seasonal Influenza Vaccination among Saudi Children: Parental Barriers and Willingness to Vaccinate Their Children.

Influenza is an acute respiratory infection. It is a contagious viral illness which can cause moderate to severe symptoms. However, high-risk groups, including children, can develop a severe condition requiring hospitalization that may, in severe cases, result in death. This study aimed to assess the knowledge and attitudes of Saudi parents toward the influenza vaccine and identify potential barriers to receiving the influenza vaccination. A cross-sectional survey was conducted using a questionnaire comprising 27 validated questions to assess parental awareness, knowledge, and attitudes toward the influenza vaccine. The overall attitude of the participants was positive (94.7%). However, their knowledge was generally poor (61.7%). Most participants were aware of the seasonal influenza vaccine (85.5%) and their children were up-to-date with the child national vaccination program vaccines (92.7%). Medical staff and awareness campaigns were the commonest sources of vaccine information. Significant predictors for knowledge about and attitudes toward the influenza vaccine included educational level, working in the medical field, monthly income, awareness of the seasonal influenza vaccine, having received the vaccine as parent, and having a child already vaccinated. Adherence to the influenza vaccination regimen for parents and their children was low. More educational campaigns are needed to increase knowledge about the vaccine.

Orthodontic Treatment Consideration in Diabetic Patients.

Although orthodontic treatment is commonly indicated for young healthy individuals, recent trends showed an increase in number of older individuals undergoing orthodontic interventions. The increased age resulted in a proportionate increase in the prevalence of systemic diseases facing dentists during orthodontic procedures, especially diabetes mellitus. This necessitates that dentists should be aware of the diagnosis of diabetes mellitus and its early signs particularly in teeth and oral cavity. It is also essential for them to understand the implications of diabetes on orthodontic treatment and the measures to be considered during managing those patients. In this review, we focused on the impact of diabetes mellitus on orthodontic treatment. We also summarized the data from previous studies that had explained the measures required to be taken into consideration during managing those patients. We included both human and animal studies to review in depth the pathophysiological mechanisms by which diabetes affects orthodontic treatment outcome. In conclusion, this review emphasizes the need to carefully identify early signs and symptoms of diabetes mellitus in patients demanding orthodontic treatment and to understand the considerations to be adopted before and during treating these patients.