RESUMO
Interstitial nephritis and immune complex-mediated glomerulonephritis are the two common renal manifestations of primary Sjögren's syndrome (SS). Here, we discuss three cases of primary SS where presenting manifestation was distal renal tubular acidosis. The possibility of an underlying autoimmune disorder should be considered in a patient presenting with distal tubular acidosis or recurrent hypokalemic periodic paralysis as treatment of primary disease improves the outcome of illness.
Assuntos
Acidose Tubular Renal/imunologia , Paralisia Periódica Hipopotassêmica/imunologia , Síndrome de Sjogren/imunologia , Acidose Tubular Renal/diagnóstico , Acidose Tubular Renal/tratamento farmacológico , Adulto , Biópsia , Suplementos Nutricionais , Feminino , Humanos , Hidroxicloroquina/uso terapêutico , Paralisia Periódica Hipopotassêmica/diagnóstico , Paralisia Periódica Hipopotassêmica/tratamento farmacológico , Túbulos Renais Distais/imunologia , Túbulos Renais Distais/patologia , Potássio/uso terapêutico , Recidiva , Glândulas Salivares/imunologia , Glândulas Salivares/patologia , Síndrome de Sjogren/complicações , Síndrome de Sjogren/diagnóstico , Síndrome de Sjogren/tratamento farmacológico , Esteroides/uso terapêutico , Resultado do TratamentoRESUMO
Renal complications due to organophosphate poisoning are very rare. We are presenting a unique case of transient distal renal tubular acidosis due to organophosphate poisoning, which to the best of our knowledge is the first of its kind. An elderly female after deliberate self-harm with ingestion of chlorpyrifos had multiple ventricular arrhythmias due to hypokalemia secondary to distal renal tubular acidosis which improved completely after treatment.