RESUMO
Capnocytophaga canimorsus is a fastidious, capnophilic and facultative anaerobic Gram-negative rod found commonly in the oral flora of dogs that may cause zoonotic infections such as cellulitis and eye infections. In immunocompromised patients, it may cause fulminant sepsis. Meningitis due to C. canimorsus is, however, a rare manifestation. This is the first reported case of C. canimorsus meningitis in Australia in an immunocompetent veterinarian diagnosed by 16s ribosomal RNA polymerase chain reaction.
Assuntos
Mordeduras e Picadas , Infecções por Bactérias Gram-Negativas , Meningite , Médicos Veterinários , Humanos , Animais , Cães , RNA Ribossômico 16S/genética , Capnocytophaga/genética , Reação em Cadeia da Polimerase , Infecções por Bactérias Gram-Negativas/diagnóstico , Mordeduras e Picadas/complicaçõesRESUMO
Cognitive dysfunction (CD) is pervasive in individuals who have chronic spinal cord injuries (SCI). Although classically associated with concomitant traumatic brain injuries, many other causes have been proposed, including premorbid neuropsychological conditions, mood disorders, substance abuse, polypharmacy, chronic pain and fatigue, sleep apnea, autonomic dysregulation, post-intensive care unit syndrome, cortical reorganizations, and neuroinflammation. The consequences of CD are likely widespread, affecting rehabilitation and function. CD in those with SCI should be recognized, and potentially treated, in order to provide the best patient care.
Assuntos
Lesões Encefálicas/complicações , Lesões Encefálicas/psicologia , Disfunção Cognitiva/etiologia , Disfunção Cognitiva/psicologia , Traumatismos da Medula Espinal/complicações , Traumatismos da Medula Espinal/psicologia , Humanos , Testes NeuropsicológicosRESUMO
Corynebacterium accolens is a rare human pathogen. We encountered a case of C. accolens isolated from a thigh collection in a man with osteomyelitis of the adjacent pubic symphysis.
Assuntos
Infecções por Corynebacterium/diagnóstico , Corynebacterium/isolamento & purificação , Osteomielite/diagnóstico , Sínfise Pubiana/microbiologia , Sínfise Pubiana/patologia , Idoso , Antibacterianos/farmacologia , Corynebacterium/classificação , Corynebacterium/genética , Infecções por Corynebacterium/microbiologia , DNA Bacteriano/química , DNA Bacteriano/genética , DNA Ribossômico/química , DNA Ribossômico/genética , Humanos , Masculino , Testes de Sensibilidade Microbiana , Dados de Sequência Molecular , Osteomielite/microbiologia , RNA Ribossômico 16S/genética , Análise de Sequência de DNARESUMO
OBJECTIVES: To describe the use and outcomes of outpatient antimicrobial therapy (OPAT) for infective endocarditis (IE) within the Canterbury region of New Zealand over an 8 year period. METHODS: All cases of IE admitted to Christchurch Hospital were reviewed. Prospectively collected data from our OPAT service's database and retrospective data from case notes were analysed. RESULTS: There were 213 episodes of IE meeting modified Duke Criteria over this time. Patients received OPAT in 100 episodes. Viridans streptococci were the infecting organism in 34, Staphylococcus aureus in 27, and enterococci in 10. Adverse events were encountered in 27 episodes. Of these, 24 were related to intravenous lines, infusion devices or adverse drug reactions which resolved with change of treatment. There were 3 serious adverse events which were likely to have occurred in hospital. During 12-month follow-up there were 5 further episodes of IE and 2 deaths unlikely to be directly related to the episode of IE. CONCLUSIONS: Despite significant co-morbidities and complications, nearly half of all patients with IE, including those with disease due to S. aureus and enterococci, successfully completed their treatment as outpatients. Continuous infusion devices were successfully used in 32 patients, including 22 with disease due to S. aureus.