[Systemic factors of acute pancreatitis advance].

In experimental studies the sequence of vitals series lesion is established at various forms of acute experimental pancreatitis (edematous pancreatitis, a pancreatonecrosis). It is shown that one of the first in pathological process involves an intestine, then - a liver, further - kidneys. It is established that at acute pancreatitis the basis of a target organs lesion is membranodestruktivny process due to excess activity of lipids peroxidation processes and phospholipase systems which are registered not only in a blood plasma, but also in tissue structures of the studied organs - an intestine, a liver, kidneys (systemic distress damages of oxidative and phospholipase induced character) acts.