Is the Grass Really Greener? The Influence of Gender Identity and Sexual Orientation on Mate Copying Behaviors.

Mate copying is a sexual strategy whereby individuals attend to socially available information about their prospective mate. This allows for more accurate decision making in regard to mating. This phenomenon was originally demonstrated among nonhumans, but there is an increasing weight of evidence suggesting that humans also engage in mate copying. Research typically focuses on heterosexual cisgender women, with no previous studies having looked at those identifying outside of the traditional gender binary. The current study aimed to address this gap by examining the impact of gender identity and sexual orientation on the propensity to engage in mate copying. Participants (N = 831) completed an online survey providing desirability ratings for photographs alone (T1) and then rated the same photographs after receiving social information about the relationship status and previous relationship history of the pictured individual (T2). It was found that both gender identity (F(4, 713) = 3.94, ηp2 = .02) and sexual orientation (F(4, 713) = 4.40, ηp2 = .02) influenced an individual's overall propensity to mate copy, and that desirability patterns for individuals were very different depending on these variables. It was concluded that while mate copying certainly is evident among humans, the phenomenon is extremely nuanced and sensitive.

Effect of Sexual Racism on Partner Desirability in Gay Asian Men.

Sexual racism-including or excluding racial minority members in partner selection based on race-negatively affects Asian men who have sex with men (MSM) across various domains. The current study aims to investigate the effect of potential partners' racial preferences on desirability in Asian MSM. The relationship between sexual racism awareness and partner desirability when evaluating white partners with racial preferences was also investigated. A sample of Asian MSM (N = 128) responded to hypothetical online dating scenarios in which the racial background (Asian/white) and racial preference (none/Asian/white) of facial stimuli were manipulated. A two-way ANOVA with post-hoc Bonferroni analyses confirmed that, as hypothesized, among potential white partners, those that exhibited no racial preferences were most desirable, F(1.66, 210.54) = .11.37, p < .001, ηp2 = .08. Among potential Asian partners, those that preferred white men were least desirable, F(1.82, 231.60) = 81.95, p < .001, ηp2 = .39. Unexpectedly, there was no relationship evident between sexual racism awareness and desirability for potential white partners (in any racial preference condition; all rs < .20). Our findings suggest that overt expression of certain racial preferences can negatively affect desirability in online dating applications.

Was it Good for You? Gender Differences in Motives and Emotional Outcomes Following Casual Sex.

Casual sex, also referred to as a hookup, has been associated with a range of negative emotional outcomes for women, including regret, anxiety, depression and social stigma. However, it has been argued that it is the nature of the sexual motivation, not gender that influences the emotional outcome. This study was designed to ascertain what motivates people to have casual sex, what emotional outcomes follow casual sex and whether there are gender differences among these variables. Seven hundred and one participants (47% men and 52.8% women) completed a 44-item online survey. Gender differences were found for both sexual motivations and emotional outcomes of casual sex, with women generally having more negative emotional outcomes than men. Additionally, a principal components analysis uncovered four reliable principal motivations underlying engagement in casual sex, and three principal emotional outcomes of casual sex. Predictors of negative emotional outcomes included being motivated to regulate negative emotions and to achieve positive emotions. No predictors (apart from being a man) were found for a positive emotional outcome. While the stigma surrounding female sexual agency is diminishing, results generally support the presence of a sexual double-standard which encourages male promiscuity but dissuades female sexual autonomy.

I want what she's having: evidence of human mate copying.

A variety of non-human females do not select male partners independently. Instead they favor males having previous associations with other females, a phenomenon known as mate copying. This paper investigates whether humans also exhibit mate copying and whether consistent positive information about a man's mate value, and a woman's age and self-perceived mate value (SPMV), influence her tendency to copy the mate choices of others. Female university students (N = 123) rated the desirability of photographed men pictured alone or with one, two, or five women represented by silhouettes. In accordance with the visual arrays, men were described as currently in a romantic relationship; having previously been in one, two, or five relationships; or not having had a romantic relationship in the past 4 years. Women generally rated men pictured with one or two previous partners as more desirable than those with none. Men depicted with five previous partners, however, were found to be less desirable. Younger, presumably less experienced women had a greater tendency to mate copy compared with older women, but high SPMV did not predict greater levels of mate copying. The findings reaffirmed and expanded those suggesting that women do not make mate choices independently.

Physicochemical characterization and biological activity of synthetic TLR4 agonist formulations.

Immunostimulatory molecules such as monophosphoryl lipid A (MPL), a Toll-like receptor 4 (TLR4) agonist, can be formulated to enhance vaccine adjuvant effects and to promote a Th1-type immune response. This study compares the in vitro and in vivo potency of aqueous and emulsion formulations containing a synthetic MPL analogue. In addition, formulation structure and association of the synthetic TLR-4 agonist and antigen with the formulation are characterized using dynamic light scattering, zeta potential measurement, HPLC, and SDS-PAGE. The biological and biophysical effects of formulating the agonist with different oil and surfactant components from animal, plant, and synthetic sources are examined. These findings have important implications for the formulation of TLR4 agonists as well as the influence of formulation component substitution on adjuvant activity. The results indicate that (1) the agonist is associated with the oil droplets in emulsion formulations, (2) the emulsion formulations containing synthetic TLR4 agonist induce higher IgG2a/IgG1 antibody ratios than aqueous formulations or an emulsion formulation without the agonist, and (3) appropriate plant-derived components can be substituted for animal-derived components in oil-in-water emulsions without loss of biological activity.

Monitoring the effects of component structure and source on formulation stability and adjuvant activity of oil-in-water emulsions.

Oil-in-water emulsions have shown promise as safe and effective adjuvant formulations for vaccines. In particular, formulations consisting of metabolizable oils such as shark-derived squalene and detergents such as egg phosphatidylcholine have been used to produce stable vaccine emulsion formulations. However, there is an emphasis in pharmaceutical regulatory bodies on using synthetic or plant-derived components from sustainable sources instead of animal-derived components. This study compares the physicochemical properties and biological efficacy of emulsions consisting of oil and detergent components from animal, plant, and synthetic sources. In particular, effects of component structure and source on emulsion stability and biological activity are examined. It is shown that oil-in-water emulsions using animal-derived components can be substituted with synthetic or plant-derived materials while still exhibiting satisfactory physicochemical and biological properties.

Oxidase, superoxide dismutase, and hydrogen peroxide reductase activities of methanobactin from types I and II methanotrophs.

Methanobactin (mb) is a copper-binding chromopeptide that appears to be involved in oxidation of methane by the membrane-associated or particulate methane monooxygenase (pMMO). To examine this potential physiological role, the redox and catalytic properties of mb from three different methanotrophs were examined in the absence and presence of O(2). Metal free mb from the type II methanotroph Methylosinus trichosporium OB3b, but not from the type I methanotrophs Methylococcus capsulatus Bath or Methylomicrobium album BG8, were reduced by a variety of reductants, including NADH and duroquinol, and catalyzed the reduction of O(2) to O(2)(-). Copper-containing mb (Cu-mb) from all three methanotrophs showed several interesting properties, including reductase dependent oxidase activity, dismutation of O(2)(-) to H(2)O(2), and the reductant dependent reduction of H(2)O(2) to H(2)O. The superoxide dismutase-like and hydrogen peroxide reductase activities of Cu-mb were 4 and 1 order(s) of magnitude higher, respectively, than the observed oxidase activity. The results demonstrate that Cu-mb from all three methanotrophs are redox-active molecules and oxygen radical scavengers, with the capacity to detoxify both superoxide and hydrogen peroxide without the formation of the hydroxyl radicals associated with Fenton reactions. As previously observed with Cu-mb from Ms. trichosporium OB3b, Cu-mb from both type I methanotrophs stimulated pMMO activity. However, in contrast to previous studies using mb from Ms. trichosporium OB3b, pMMO activity was not inhibited by mb from the two type I methanotrophs at low copper to mb ratios.