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Drug Dev Res ; 84(8): 1572-1577, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-37587871

RESUMO

Animal testing is required in drug development research and is crucial for assessing the efficacy and safety of medications before they are commercialized. However, the newly furnished Food and Drug Administration Modernization Act 2.0 has given new insight into drug development. It opens a new door by offering an alternative testing method for developing a new drug without using animals. This newly proposed system may potentially significantly impact nondeveloped countries worldwide. In this study, we explore the alternative testing options such as in silico modeling, human tissue-on-chip engineering, animal-free recombinant antibodies, tissue engineering, and artificial intelligence presented by this act and discuss its implications for nondeveloped countries.


Assuntos
Inteligência Artificial , Aprovação de Drogas , Animais , Estados Unidos , Humanos , Preparações Farmacêuticas , Desenvolvimento de Medicamentos , United States Food and Drug Administration
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