Effect of a Customized Panchakarma (bio-purificatory) Treatment Plan in a Case of Urethral Stricture with Cystitis: A Case Report.

Objectives: Cystitis, inflammation of the bladder due to urinary tract infection, and Urethral stricture, narrowing of the urethra that obstructs the urine flow are conditions often aligned with the Ayurvedic concept of Mutraghata (urinary obstruction). This case report aims to evaluate the effectiveness of an Ayurvedic treatment protocol, including Udwartana (powder massage), Virechana (purgation), and Uttara Basti (enema) (urethral douche) on the parameters of Uroflowmetry. Methodology: A patient diagnosed with cystitis and urethral stricture underwent a series of Panchakarma (bio-purificatory) procedures. The protocol included Udwartana (powder massage), Avagaha Swedana (sitz bath), Virechana (purgation), Niruha Basti (enema) (decoction enema), Uttara Basti (enema) (urethral douche) using medicated decoctions and oils on alternate days. Post-discharge, the patient continued oral Ayurvedic medications at home. Uroflowmetry was employed to assess treatment effectiveness before and after the intervention. Results: Marked improvements were observed in Uroflowmetry parameters, including maximum flow rate, average flow rate, and voiding time along with a reduction in symptoms such as frequent urination, burning sensation during micturition, reduced flow, and the patient reported an enhanced quality of life, with better performances in daily activities. These improvements were sustained during the 60- day follow-up period. Conclusion: A combination of modified Uttara Basti (transurethral douche) and other panchakarma procedures, plus oral Ayurvedic medications was effective in relieving the symptoms of urethral stricture and improving Uroflowmetry parameters with sustained results during the 60-day follow-up period.

Therapeutic influence of some dietary articles on gut microbiota in the pathogenesis of rheumatoid arthritis (Amavata) - A review.

BACKGROUND: Amavata is a chronic immune­inflammatory systemic disorder caused by the formation of Ama and its association with Vata at Kaphasthana (joints) and can be simulated with rheumatoid arthritis (RA). Published evidences show that treatment indicated in Amavata is effective in RA. Increased inflammatory status in RA is suggestive of gut dysbiosis involving gut microbiota (GM). AIM: The aim of the present study was to analyze the influence of diet on GM of RA patients based on Pathya (dietary advice) mentioned for Amavata. MATERIALS AND METHODS: Laghutrayis such as Bhavaprakasha Samhita, Madhava Nidana and Sharangadhara Samhita, Bhaishajya Ratnavali and Nighantus (Sanskrit glossary) such as Raja Nighantu, Bhavaprakasha Nighantu and Yogaratnakara, Ashtanga Hridaya also different databases were reviewed for Pathya of Amavata. Different databases such as PubMed, Scopus, DHARA, Google Scholar, Science Direct were searched with research papers establishing the role of nonnutritive bioactive components in horse gram, barley, garlic, ginger, drumstick leaves, cow urine and buttermilk in the management of RA were also reviewed. It was found that Pathya influences on the GM by lowering or inhibiting inflammatory markers such as interleukin­6 (IL­6), 17 and leukotrines through Bowman­Birk inhibitors and polyphenolic compounds. Among them, Takra is already a proven probiotic. Gomutra augments B and T lymphocytes, IL­1 and IL­2, strengthening the immune system. CONCLUSION: It was concluded that Pathya Ahara mentioned for Amavata have a direct link with GM of RA patients. Even though the pharmacological actions have been clinically proven/practised, this review creates evidence for its scientific basis.