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3.
Cureus ; 14(3): r41, 2022 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-35342675

RESUMO

[This retracts the article DOI: 10.7759/cureus.18401.].

4.
Cureus ; 13(10): e19133, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34868771

RESUMO

Xanthogranulomatous pyelonephritis is a rare chronic infectious process of the kidney, which has been described in three different forms: diffuse, segmental, and focal. It is also known as the great simulator since its clinical, radiological, and histopathological manifestations tend to be confused with other entities. We describe a case of a 55-year-old male patient with two months of clinical manifestations characterized by a 7x7-cm palpable mass in his right lumbar region, which was hot and painful upon touch and increasing in size. This article aims to present a case of xanthogranulomatous pyelonephritis and compare it with its primary differential diagnoses. It is evident that despite the condition being considered a simulating pathology, some key differences can be found to identify and distinguish it.

5.
Cureus ; 13(11): e19354, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-34909315

RESUMO

Introduction Double J stents (DJS) are commonly used in urological practice, but they do have a risk of complications, such as infection and hematuria. This study explored the association between ureteral double J stent colonization and lower urinary tract symptom (LUTS) severity. Methodology This cross-sectional study was conducted from January 2021 to June 2021 in patients admitted to a tertiary care hospital in Karachi, Pakistan, who required double J stent (DJS) insertion. Patients who came to the site for stent removal were invited to participate in the study and enrolled using a consecutive sampling technique between January 15, 2021, and March 15, 2021. Results The study enrolled 176 patients, of whom 73.33% had colonization and the remaining had no colonization. The factors significantly associated with symptom severity included colonization of the DJS (P-value = 0.001) and the patients' ages (P-value = 0.046). The two groups have significantly different symptoms, which included incontinence (P-value = 0.001), polyuria (P-value = 0.001), and nocturia (P-value = 0.001). Conclusion Our study found more severe symptoms in DJS patients with colonization than in those without colonization. Irritative voiding symptoms, including nocturia and dysuria, are more common in DJS patients with colonization.

6.
Cureus ; 13(11): e19407, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-34909327

RESUMO

Posterior reversible encephalopathy syndrome (PRES) is a clinical-radiological entity characterized by variable neurological manifestations, primarily caused by pathophysiological changes related to cerebral autoregulation that result in radiologically evident vasogenic edema. It is usually associated with hypertensive states, but it is not exclusively related to those.  A healthy 18-year-old primigravid woman with no proteinuria or hypertension on admission presented with normotensive PRES. She had an intense diffuse headache that preceded a generalized tonic-clonic seizure. Her neurological status deteriorated, and hypertension was detected afterward. Brain imaging revealed bilateral vasogenic edema in the occipital region. Magnesium sulfate and antihypertensive medications were administered. A cesarean section was performed, and her neurological symptoms subsequently improved, leading to discharge with no complications.  This case highlights the importance of suspecting PRES in pregnant patients even in the absence of preeclampsia.

7.
Cureus ; 13(9): e18401, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-34729278

RESUMO

BACKGROUND:  The aim of this study is to assess the correlation and agreement between venous blood gas (VBG) values and arterial blood gas (ABG) values in patients presented in the emergency department of the Indus Hospital, Karachi. This study also included the evaluation of specificity and sensitivity of VBGs values for the identification of abnormal ABG values. METHOD: It was a retrospective, observational study conducted at the Indus Hospital and Health Network, Karachi, Pakistan. All VBG and ABG values in the same patient which were collected at the same time from April 2020 to May 2021 were included in the study.  Results: The study involved 377 patients; 52.8% of patients were female, while 47.2% were male. The mean age of patients was 53.4 years (±17.2). There is an acceptable agreement between the arterial and venous values of pH, bicarbonate (mEq/l), and lactate (mEq/l), respectively, and poor agreement in PCO2 (mmHg) and PO2. CONCLUSION: The study found that analysis of VBG has the potential to be used in the emergency setting in general. Blood gas values of Lactate, HCO3, and pH have shown acceptable association and significant correlation, and they can be considered clinically interchangeable with ABGs values. However, venous PCO2 and PO2 were found to be different between the two.

8.
Cureus ; 13(10): e18803, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34796076

RESUMO

Introduction Multimorbidity is defined as the coexistence of more than one chronic condition in one individual. It is related to enhanced rates of disability and mortality, enhanced disease burden, decreased function levels, and it can affect the wellbeing and daily activities of people, including loss of autonomy and independence. The aim of the current study is to determine the predictors of quality of life among patients with multimorbidity in Karachi, Pakistan. Methodology It was a cross-sectional study conducted in 12 health care facilities of six districts in Karachi, Pakistan. Two health care facilities were selected from each district using a convenient sampling technique. The total sample size of this study was 690, equally distributed among 12 health care facilities. Results The majority of participants (33.47%) belonged to the age group of 40 to 49 years, while 29.85% of participants had an age between 30 to 39 years. More than half of the participants were females (50.87%). Overall, the multivariate analysis showed being male, married, younger, high educational status and employed were positively associated with quality of life. While having lower family income is negatively associated with quality of life. Conclusion The findings of this study had important implications for identifying distinct multimorbidity individuals who were at risk of a lower quality of life, and they emphasized the need for disease detection and treatment at an early stage. The study can also give important evidence for decision-makers when it comes to allocating health resources more efficiently, and health administrative departments can improve chronic disease management.

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