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1.
Adv Colloid Interface Sci ; 331: 103199, 2024 May 19.
Artigo em Inglês | MEDLINE | ID: mdl-38909548

RESUMO

Recently, the availability of point-of-care sensor systems has led to the rapid development of smart and portable devices for the detection of hazardous analytes. The rapid flow of artificially ripened fruits into the market is associated with an elevated risk to human life, agriculture, and the ecosystem due to the use of artificial fruit ripening agents (AFRAs). Accordingly, there is a need for the development of "Point-of-care Sensors" to detect AFRAs due to several advantages, such as simple operation, promising detection mechanism, higher selectivity and sensitivity, compact, and portable. Traditional detection approaches are time-consuming and inappropriate for on-the-spot analyses. Presented comprehensive review aimed to reveal how such technology has systematically evolved over time (through conventional, advanced, and portable smart techniques) detection detect AFRA, till date. Moreover, focuses and highlights a framework of initiatives undertaken for technological advancements in the development of smart the portable detection techniques (kits) for the onsite detection of AFRAs in fruits with in-depth discussion over sensing mechanism and analytical performance of the sensing technology. Notably, colorimetric detection methods have the greatest potential for real-time monitoring of AFRA and its residues because they are easy to assemble, have a high level of selectivity and sensitivity, and can be read by the human eye independently. This study sought to differentiate between traditional credible strategies by presenting new prospects, perceptions, and challenges related to portable devices. This review provides systematic framework of advances in portable field recognition strategies for the on-spot AFRA detection in fruits and critical information for development of new paper-based portable sensors for fruit diagnostic sectors.

2.
Pak J Pharm Sci ; 29(5 Suppl): 1877-1880, 2016 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-28476717

RESUMO

Ulcerative colitis is an inflammatory disease of the large intestine whose effects are bloody diarrhea, cramping and bloating. The disease is usually relapsing and remitting. However, the cause of ulcerative colitis is not yet known. Due to this reason, finding an effective treatment has been a great challenge. The suggested medical treatment is usually composed of two portions; keeping the flare up from happening and treating the flare up when it has happened. Active flare ups are treated with corticosteroids. There are several hypothesis which suggest that ulcerative colitis could be due to the micro flora present in gut. For this reason, several researchers tried to modify the gut microflora with probiotics. However, there is no probiotics found that can induce emission faster than the placebo. The ulcerative colitis patients taking probiotics showed fewer and less severe symptoms during the flare up. This means that even though the probiotics did not end up the flare up faster, it slowed up the severity of the symptoms of the patients.


Assuntos
Colite Ulcerativa/fisiopatologia , Probióticos , Humanos
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