Assuntos
Disco Óptico , Doenças do Nervo Óptico , Neoplasias do Nervo Óptico , Angiofluoresceinografia , Humanos , Necrose/complicações , Necrose/diagnóstico , Disco Óptico/diagnóstico por imagem , Doenças do Nervo Óptico/complicações , Doenças do Nervo Óptico/etiologia , Neoplasias do Nervo Óptico/complicações , Neoplasias do Nervo Óptico/diagnósticoAssuntos
Fóvea Central/anormalidades , Hiperopia/diagnóstico , Hiperopia/patologia , Adulto , Idoso , Feminino , Angiofluoresceinografia , Fóvea Central/irrigação sanguínea , Fóvea Central/patologia , Humanos , Hiperopia/complicações , Pessoa de Meia-Idade , Vasos Retinianos/anormalidades , Vasos Retinianos/patologia , Índice de Gravidade de Doença , Tomografia de Coerência ÓpticaRESUMO
OBJECTIVE: We aimed to present patients with the Mayer-Rokitansky-Küster-Hauser syndrome (MRKH) coming from one center and presenting all the possibilities of its treatment, at the forefront with the uterine transplantation. PATIENTS AND METHODS: The presented work is an example of different types of MRKH syndrome diagnosed in 25 women who were diagnosed in the Department of Gynecological Endocrinology due to the primary amenorrhea from 01/2001 to 06/2018. RESULTS: Patients suffering from MRKH syndrome are capable of having genetic offspring but are unable to give birth to their own child, due to an absence of the uterus, blindly terminated vagina, and normal ovaries. Patients suffering from this syndrome have the opportunity to receive treatment in accordance with their current needs. However, there are many medical, technical, and ethical limitations in achieving the most important therapeutic target: uterine transplantation and childbirth. CONCLUSIONS: Until a few years ago, patients with an absolute uterine factor of infertility, including women with MRKH syndrome, had a real choice of only two equally controversial options giving a chance for motherhood - surrogacy and adoption. However, modern transplantation has shown that a third option - a uterine transplant - exists and is available.
Assuntos
Transtornos 46, XX do Desenvolvimento Sexual/diagnóstico , Transtornos 46, XX do Desenvolvimento Sexual/cirurgia , Anormalidades Congênitas/diagnóstico , Anormalidades Congênitas/cirurgia , Ductos Paramesonéfricos/anormalidades , Útero/transplante , Transtornos 46, XX do Desenvolvimento Sexual/fisiopatologia , Adolescente , Adulto , Anormalidades Congênitas/fisiopatologia , Feminino , Previsões , Humanos , Ductos Paramesonéfricos/fisiopatologia , Ductos Paramesonéfricos/cirurgia , Transplante de Órgãos/métodos , Transplante de Órgãos/tendências , Resultado do Tratamento , Útero/irrigação sanguínea , Útero/fisiologia , Adulto JovemRESUMO
Colic, or persistent unexplained crying in infants, is a disorder commonly encountered by the family physician. Although colic is not detrimental to an infant's health, it can place tremendous stress on the family. No effective cure for this disorder is known. Researchers have investigated a wide variety of therapies, including formula changes, pharmacotherapy and infant positioning maneuvers, but study results have been conflicting, controversial and inconclusive. At present, behavioral management, supportive counseling and parental reassurance are the mainstays of treatment. By formulating an effective individualized management plan, the family physician can help assist parents through the trying period of infantile colic.