Arrhythmogenic right ventricular cardiomyopathy with sustained ventricular tachycardia: a case report.

INTRODUCTION: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an infrequent hereditary disorder distinguished by fibrofatty replacement of the myocardium in the right ventricular, which predisposes individuals to life-threatening arrhythmias. This case delineates an ARVC patient who suffered recurrent bouts of sustained ventricular tachycardia (VT). In this case, we mainly discuss the application of myocardial contrast echocardiography (MCE) in displaying myocardial fibrosis in patients with ARVC. CASE PRESENTATION: A 43-year-old male experienced three episodes of unexplained VT over an eight-year period, accompanied by symptoms of chest discomfort, palpitations and dizziness. Coronary angiography revealed no significant coronary stenosis. The electrocardiogram (ECG) results indicated characteristic epsilon waves in right precordial leads, and subsequent echocardiography identified right ventricular enlargement and right ventricular systolic dysfunction. MCE further disclosed regional myocardial ischemia at the epicardium of the left ventricular apex. Ultimately, cardiovascular magnetic resonance imaging (CMR) corroborated the ARVC diagnosis, highlighting linear intensification in the right ventricle during the delayed enhancement. CONCLUSION: Prompt identification of ARVC is crucial for timely intervention and management. MCE may offer an effective and valuable technique for the detection of myocardial involvement in ARVC patient.

Life history responses of spring-and autumn-germinated ephemeral plants to increased nitrogen and precipitation in the Gurbantunggut Desert.

Nitrogen deposition and precipitation change are not only hot topics of current global change but also the main environmental factors affecting plant growth. Thus, the effects of nitrogen and precipitation on the life history of spring-(SG) and autumn-germinated (AG) ephemeral plants of Erodium oxyrhynchum were researched in the Gurbantunggut Desert, northern China, and the aim was to understand the response of plants from different germination seasons to global change. SG and AG plants with increased nitrogen and precipitation plus nitrogen treatments were measured to determine seedling survival, phenology, plant traits, biomass accumulation and allocation and dormancy characteristics of offspring (seeds). The results showed that increased nitrogen and precipitation plus nitrogen treatments significantly improved the survival of SG and AG plants during the seedling stage, and precipitation plus nitrogen treatments also improved the growth and seed production of SG and AG plants, but increased nitrogen significantly inhibited their growth and seed production. Therefore, precipitation plays an important role in regulating nitrogen uptake by plants in arid and semiarid ecosystems. With increased nitrogen, SG and AG plants allocated more biomass into root and reproductive organs but allocated significantly less biomass into the leaf, with almost no change in biomass allocation to the stem. With nitrogen plus precipitation treatments, biomass allocation in all organs of SG and AG plants showed almost no change. Clearly, changes in soil moisture also affected biomass allocation of SG and AG plants. For offspring dormancy, SG and AG plants produced more nondormancy seeds with increased nitrogen but produced more dormancy seeds under precipitation plus nitrogen treatments. Hence, in a harsh environment, SG and AG plants produced more nondormancy offspring with low reproduction in order to occupy the habitat rapidly in the following year or produced more dormancy offspring with high reproduction in a suitable environment intended for spreading germination risk in time and conserve the population.

Thiazole Orange derivatives: synthesis, fluorescence properties, and labeling cancer cells.

A series of Thiazole Orange (TO) derivatives were synthesized and modified by introducing different substitutional groups on benzothiazole and 4-methylquinoline All the TO derivatives were confirmed by (1)HNMR and MS. TO derivative bearing NH(2)- was modified by folic acid and used to label breast cancer cells. The phenomenon of fluorescence enhancement was shown by the fluorescence spectrums of TO derivatives and micrographs of the labeled breast cancer cells. It offered a new try in the aspect of labeling cells by the embedded dyes.