A novel titanium alloy for load-bearing biomedical implants: Evaluating the antibacterial and biocompatibility of Ti536 produced via electron beam powder bed fusion additive manufacturing process.

Additive manufacturing (AM) of Ti-based biomedical implants is a pivotal research topic because of its ability to produce implants with complicated geometries. Despite desirable mechanical properties and biocompatibility of Ti alloys, one major drawback is their lack of inherent antibacterial properties, increasing the risk of postoperative infections. Hence, this research focuses on the Ti536 (Ti5Al3V6Cu) alloy, developed through Electron Beam Powder Bed Fusion (EB-PBF), exploring bio-corrosion, antibacterial features, and cell biocompatibility. The microstructural characterization revealed grain refinement and the formation of Ti2Cu precipitates with different morphologies and sizes in the Ti matrix. Electrochemical tests showed that Cu content minimally influenced the corrosion current density, while it slightly affected the stability, defect density, and chemical composition of the passive film. According to the findings, the Ti536 alloy demonstrated enhanced antibacterial properties without compromising its cell biocompatibility and corrosion behavior, thanks to Ti2Cu precipitates. This can be attributed to both the release of Cu ions and the Ti2Cu precipitates. The current study suggests that the EB-PBF fabricated Ti536 sample is well-suited for use in load-bearing applications within the medical industry. This research also offers an alloy design roadmap for novel biomedical Ti-based alloys with superior biological performance using AM methods.

Large-aperture experimental characterization of the acoustic field generated by a hovering unmanned aerial vehicle.

Unmanned aerial vehicles, specifically quadrotor drones, are increasingly commonplace in community and workplace settings and are often used for photography, cinematography, and small parcel transport. The presence of these flying robotic systems has a substantial impact on the surrounding environment. To better understand the ergonomic impacts of quadrotor drones, a quantitative description of their acoustic signature is needed. While previous efforts have presented detailed acoustic characterizations, there is a distinct lack of high spatial-fidelity investigations of the acoustic field of a quadrotor hovering under its own power. This work presents an experimental quantification of the spatial acoustic pressure distribution in the near-field of a live hovering unmanned aerial vehicle. A large-aperture scanning microphone array was constructed to measure sound pressure level at a total of 1728 points over a 2 m × 3 m × 1.5 m volume. A physics-infused machine learning model was fit to the data to better visualize and understand the experimental results. The experimental data and modeling presented in this work are intended to inform future design of experiments for quadrotor drone acoustics, provide quantitative information on the acoustic near-field signature, and demonstrate the utility of optical motion tracking coupled with a custom microphone array for characterization of live acoustic sources.

Using robotic mechanical perturbations for enhanced balance assessment.

Balance impairment is critical for many patient groups such as those with neural and musculoskeletal disorders and also the elderly. Accurate and objective assessment of balance performance has led to the development of several indices based on the measurement of the center of pressure. In this study, a robotic device was designed and fabricated to provide controlled and repeatable mechanical perturbations to the standing platform of the user. The device uses servo-controlled actuators and two parallel mechanisms to provide independent rotations in mediolateral and anterior-posterior directions. The device also provides visual feedback of the center of pressure position to the user. Functional tests were run and showed that the device is able to provide an appropriate dynamics (time constant of 0.19 s and bandwidth of 0.85 Hz) for the two motions. The efficacy of the device on the balance assessment was then evaluated experimentally. Ten healthy subjects performed a balance task with and without perturbations and seven center of pressure indices were measured. It was shown that the sensitivity of the indices to the user's performance was statistically increased in all indices particularly in anterior/posterior direction when the mechanical perturbations were present.