RESUMO
OBJECTIVES: To study of the association between thyroid carcinoma and Hashimoto's thyroiditis (HT). MATERIAL AND METHODS: [corrected] Retrospective study of 78 patients undergoing surgery between 2001 and 2002, with a pathological diagnosis of Hashimoto's thyroiditis. The clinical data and complementary tests performed before surgery are reported. RESULTS: The mean age was 44.6 years, with 77 females and only one male. There were 12 cases of thyroid cancer associated with HT, mostly with the nodular form, with 11 papillary carcinoma (14.1%) and one non-hodgkin B lymphoma of the thyroid. Tumor size varied from 4 to 60 mm with a mean of 26 mm. There was one microcancer (size<10 mm). CONCLUSIONS: We did not find an increased incidence of thyroid cancer associated with this highly selected population of HT patients.
Assuntos
Carcinoma Papilar/complicações , Doença de Hashimoto/complicações , Linfoma de Células B/complicações , Neoplasias da Glândula Tireoide/complicações , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Carcinoma Papilar/patologia , Feminino , Doença de Hashimoto/diagnóstico , Doença de Hashimoto/diagnóstico por imagem , Doença de Hashimoto/patologia , Doença de Hashimoto/cirurgia , Humanos , Linfoma de Células B/patologia , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Testes de Função Tireóidea , Glândula Tireoide/patologia , Neoplasias da Glândula Tireoide/patologia , Tireoidectomia , UltrassonografiaRESUMO
OBJECTIVES: The management of diagnosis, treatment and outcome of malignant neoplasm arising in a lingual thyroid. MATERIAL AND METHODS: We report a case of papillary-follicular carcinoma arising in a lingual thyroid. RESULTS: Lingual carcinoma causes dysphagia and pain due to oropharyngeal obstruction. Surgical pharyngotomy with a trans-hyoid approach provides good access to the lesions. Therefore, the eutopic thyroid was present, in pretracheal position, without neoplastic proliferation. CONCLUSIONS: Carcinoma arising in lingual thyroid is an extreme rare entity. Its diagnosis is histologic. Its treatment is surgical associated with radio-iodine therapy.
Assuntos
Carcinoma Papilar, Variante Folicular , Coristoma , Glândula Tireoide , Neoplasias da Glândula Tireoide , Doenças da Língua/complicações , Neoplasias da Língua , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Carcinoma Papilar, Variante Folicular/diagnóstico , Carcinoma Papilar, Variante Folicular/patologia , Carcinoma Papilar, Variante Folicular/cirurgia , Criança , Coristoma/complicações , Transtornos de Deglutição/etiologia , Diagnóstico Diferencial , Feminino , Seguimentos , Humanos , Imuno-Histoquímica , Laringoscopia , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Glândula Tireoide/patologia , Neoplasias da Glândula Tireoide/diagnóstico , Neoplasias da Glândula Tireoide/epidemiologia , Neoplasias da Glândula Tireoide/patologia , Tireoidectomia , Fatores de Tempo , Língua/patologia , Neoplasias da Língua/diagnóstico , Neoplasias da Língua/patologia , Neoplasias da Língua/cirurgiaRESUMO
In order to study the etiology of endemic goiter in the north-western part of Tunisia, we examined 93 adolescents of this region. We measured urinary iodine concentrations, serum total thyroxine, total triiodothyronine, thyrotropin, thyroglobulin and antithyrogobulin antibody concentrations. The adolescents were questioned about their alimentary habits, the origin of their drinking water and the presence of known goiter(s) in their family. Among these adolescents, 49.5% of them had a goiter. Urinary iodine concentrations showed mild iodine deficiency. The serum determinations gave results within the reference ranges, without any significative differences between adolescents, with or without goiter. We found two risk factors: the age of adolescents, and the presence of a known goiter in the family. These results suggest that the actual prevention may not be adequate, or most likely that goitrogenic factors are to be looked for, especially in drinking water, since the majority of these adolescents drink no controlled water.