[Epidemiological and anatomopathological profile of endometriosis in Dakar: retrospective study over a period of 20 years]. / Aspects épidémiologique et anatomopathologique des endométrioses à Dakar : étude rétrospective sur une période de 20 ans.

INTRODUCTION: Endometriosis is a gynecological pathology defined by the presence and abnormal development of endometrial tissue outside the uterine cavity. Our objective was to draw up an epidemiological profile and to describe the anatomical clinical forms of endometriosis in Dakar. PATIENTS AND METHODS: This is a retrospective study of all cases of external and internal endometriosis diagnosed in an anatomy and pathology laboratory in Dakar over a period of twenty (20) years. The study parameters were collected from anonymous data sheets. Data entry and analysis were performed using version 22 of the EPI INFO and SPSS software. RESULTS: Our study involved 104 female patients. The mean age was 47.3±10.0. Among the patients with an adenomyosis condition, the mean age was 49.8 years. Patients with an external endometriosis condition had a mean age of 37.6 years. The location of the endometriosis was statistically correlated with the age of patients and with parity. Anatomically and pathologically, the surgical specimen 89.4% (n=93) was the main type of sampling that was found. The uterine body was the main location of the pathology, with 78.9% (n=82), followed by the umbilical location with 9.6% (n=10). Leiomyomas 44.07% (n=26) were the main associated lesions. CONCLUSION: Endometriosis is a gynecological pathology that is unfortunately not well known, and which is under diagnosed in Senegal.

[Phalus sarcomatoid carcinoma, a case study]. / Carcinome a cellules fusiformes (sarcomatoide) du penis. a propos d'un cas.

The sarcomatoid carcinoma is a rare histological form, high grade malignancy, aggressive and dark prognosis. We report a (01) case in a young adult of 32 years. The aim of this work is to present, through a review of the literature, the epidemiological and morphological characteristics of this affection; and also to describe the difficulties that the pathologist may encounter in diagnosis of this condition.

Le carcinome sarcomatoide en est une variante rare du carcinome épidermoïde, de haut grade de malignité, agressive et de pronostic sombre. Nous rapportons un (01) cas chez un jeune adulte de 32 ans. Le but de ce travail est de présenter à travers une revue de la littérature, les caractères épidémiologique et morphologique de cette affection ; et aussi de décrire les difficultés du diagnostic histopathologique.

[Primary cutaneous localization revealing leukemia/T-cell lymphoma associated with chronic HTLV-1 infection in a adult. A case presentation]. / Localisation cutanée révélatrice d'une leucémie/lymphome T de l'adulte.

Adult T-cell leukemia/lymphoma (ATLL) is a rare medical condition and a diagnosis that ought to be considered for patients living in an area endemic for the HTLV-1 virus (human T-lymphotrophic virus) where a T-cell lymphoproliferative diagnosis has been made. The cutaneous clinical forms may be the first manifestation of the disease. We report here an observation in a 60-year-old Senegalese woman whose skin lesions were sampled to reveal the ATLL immunophenotypic profile CD4+, CD25+, FoxP3-, and CD7-. HTLV-1 seropositivity confirmed the histopathological diagnosis, and should be corroborated by demonstration of a molecular clonal rearrangement by PCR (Polymerase Chain Reaction). This is a problem because such techniques are not always available in Africa.