Assuntos
Doenças da Coroide/diagnóstico , Infecções Oculares Bacterianas/diagnóstico , Granuloma/diagnóstico , Transtornos da Visão/diagnóstico , Doença de Whipple/complicações , Doença de Whipple/diagnóstico , Adulto , Doenças da Coroide/microbiologia , Diagnóstico Diferencial , Infecções Oculares Bacterianas/microbiologia , Granuloma/microbiologia , Humanos , Masculino , Imagem Multimodal/métodos , Transtornos da Visão/microbiologiaRESUMO
INTRODUCTION: Whereas syphilis is a classical cause of uveitis, it is still often under-recognized. Treatment recommendations are not based on specific clinical studies. CASE REPORTS: We report two patients with syphilitic uveitis diagnosed and treated at the University Hospital of Angers. Ocular involvement was inaugural in both patients. Each had a specific treatment but none had a complete recovery of visual function. CONCLUSION: Syphilis must be discussed in all patients diagnosed with uveitis or papillitis. Although not evidence-based, prompt therapy may lead to functional recovery.
Assuntos
Infecções Oculares Bacterianas/diagnóstico , Sífilis/diagnóstico , Adulto , Infecções Oculares Bacterianas/complicações , Infecções Oculares Bacterianas/fisiopatologia , Humanos , Masculino , Pessoa de Meia-Idade , Sífilis/complicações , Sífilis/fisiopatologia , Acuidade Visual/fisiologiaRESUMO
INTRODUCTION: The Niemann Pick disease type B is a rare deficiency in sphingomyelinase activity, autosomal recessively inherited. CASE REPORTS: We report three patients (two men, one woman) of the same family, who showed pulmonary and hepatosplenic lesions, usually present in the disease but also adrenal gland lesions confirmed by tomodensitometry. CONCLUSION: The current treatment of Niemann Pick disease is purely symptomatic awaiting the use of enzymatic replacement therapy which has been successfully experimented in animal model.
Assuntos
Doença de Niemann-Pick Tipo B/diagnóstico , Doença de Niemann-Pick Tipo B/genética , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
INTRODUCTION: The hemophagocytic syndrome is rare and sometimes associated with tuberculosis. OBSERVATION: We report the case of a 30-year-old migrant from Congo presenting with a recurrent right pleuropneumonia, cachexia and night sweat. Blood tests revealed bicytopenia with a normal myelogram. Thorax CT-scan showed large mediastinal lymph nodes and pleuritis. Mediastinal lymph node biopsy concluded to granulomatosis lymphadenopathy with necrosis and bone marrow biopsy suggested hemophagocytic syndrome. The outcome was favorable with antibiotics and corticosteroids.
Assuntos
Linfo-Histiocitose Hemofagocítica/etiologia , Tuberculose/complicações , Adulto , Humanos , MasculinoRESUMO
Scarlet fever is a rare disease in adult patients. We report a patient in whom scarlet fever was associated with hypertrophic gastritis and multiple organ failure. A 62-year-old woman presented with septic shock and multiple organ failure. Bacteriological survey was negative. Abdominal tomodensitometry showed an hypertrophic gastritis. Histological analysis demonstrated a non specific gastritis without any tumoral sign. Cefotaxime and amoxicillin led to improvement and hypertrophic gastritis progressively resolved. A sandpaper rash over the body with finger desquamation, elevation of antistreptolysin O and a recent contact with an infected grandson led to the diagnosis of scarlet fever. Due to antibiotic prescription, scarlet fever is now uncommon. Although classical, ENT or gastroenteritis presentations may be puzzling for the diagnosis of scarlet fever. As 150 years ago, diagnosis of scarlet fever is still a clinical challenge.