Self-Description of a University-Community Partnership to Advocate for Restroom Access Policy Change in Chicago.

BACKGROUND: Transgender, nonbinary, and gender-non-conforming individuals face significant obstacles accessing public restrooms, resulting in negative mental and physical health consequences. OBJECTIVES: We describe the Chicago Restroom Access Project, a university and community partnership aimed at reforming restroom laws in Chicago and the state of Illinois. METHODS: A range of community-engagement approaches were used, including recruiting, mobilizing, and partnering with diverse stakeholders, amplifying the voices of under-represented members of the impacted community, collecting data for evidence-based decision-making, fluid membership, and diffuse leadership. RESULTS: Outcomes included developing resources for public education, changing the City of Chicago Human Rights Ordinance, changing Illinois state law on single-occupancy restrooms, and implementing restroom reform at an educational institution. Lessons learned are also described. CONCLUSIONS: The methods and principles of this partnership provide approaches that can be used to advocate for reform and policy change for restroom access throughout the country.

Efficacy and safety of a novel moldable, resorbable, and degradable sealant of bone surfaces for hemostasis after bone graft harvesting from the iliac crest.

STUDY DESIGN: A prospective, controlled, open, randomized multicenter study. OBJECTIVE: The study's objective was to demonstrate equivalence of a novel, moldable, resorbable, and degradable synthetic polymer (Bone Seal) compared with a collagen fleece (Lyostypt) in efficacy and safety for topical hemostasis after iliac crest bone graft harvesting. SUMMARY OF BACKGROUND DATA: Harvesting cortico-cancellous bone from the iliac crest is a well established procedure in orthopedic and particularly in spine surgery. It is associated with significant morbidity at the donor site where hematoma formation may cause impaired wound healing and infections in up to 10% of cases. METHODS: A total of 112 patients were included in the safety analysis. Safety was determined by a compound wound healing score and the incidence of adverse clinical effects. One hundred and eight patients were studied for equivalence in efficacy using a compound bleeding score. The handling properties and the application to the bone surface of either device were measured with two additional compound scores. RESULTS: The mean bleeding scores in the final analysis was 4.5 +/- 1.3 for the Bone Seal group and 4.2 +/- 1.3 for the collagen fleece group. Bone Seal was better applicable to the bleeding bone surfaces than the collagen fleece, even though its handling was more complicated. Wound healing and the incidences of adverse clinical events were comparable in either study group. CONCLUSIONS: Bone Seal is an effective and safe hemostatic material for sealing bleeding bone surfaces after iliac crest bone graft harvesting. By virtue of its hemostatic efficacy, Bone Seal is preventive for wound healing disorders.