[Functional results of surgical treatment of patients with various types of acquired cholesteatoma]. / Funktsional'nye rezul'taty khirurgicheskogo lecheniya patsientov s razlichnymi tipami priobretennoi kholesteatomy.

OBJECTIVE: To study the long-term functional results of surgical treatment of patients with acquired cholesteatoma, their dependence on the age of patients, the type of cholesteatoma and the type of surgery. MATERIAL AND METHODS: The article presents the results of a dynamic comparison of the functional results of surgical treatment of 332 adults and 104 children with various forms of acquired middle ear cholesteatoma who underwent both closed and open surgical procedures. RESULTS: There were no statistically significant differences in hearing function into two age's groups depending on the type of cholesteatoma acquired. Average air conduction in adult patients for all types of cholesteatoma were ranked within 34.55-44.19 dB, air-bone gaps - 24.14-31.12 dB; in children - 33.72-39.16 dB and 27.33-34.95 dB, respectively. The exception was a group of adult patients with secondary cholesteatoma of the pars tensa. In the postoperative period, in patients of both age groups with all types of cholesteatoma, an improvement in the average values of air conduction by 18-20 dB and a decrease in the average values of the air-bone thresholds by 17-21 dB were noted. Analysis of the results of open surgical interventions showed a somewhat worse functional efficiency on 5-9 dB for air conduction average and 18-20 dB for air-bone gaps, both for adults and children. The stability of the achieved level of auditory function at all stages of postoperative observation was also noted. CONCLUSION: Surgical treatment of children and adult with all types of acquired cholesteatoma can improve hearing function and achieve stable results when using closed or open types of operations.

[Predictors of recurrent pathology and prognosis of the results of surgical treatment of patients with acquired middle-ear cholesteatoma]. / Prediktory retsidiviruyushchei patologii i prognoz rezul'tatov khirurgicheskogo lecheniya patsientov s priobretennoi kholesteatomoi srednego ukha.

A retrospective analysis of the results of surgical treatment of 436 patients (332 adults and 104 children under the age of 15 years) with acquired middle ear cholesteatoma was performed to identify possible predictors of relapse of the process and a prospective assessment of the results of surgical treatment. It was revealed that the leading factors in the development of residual pathology were: the presence of cholesteatoma in the area of destruction of the bone wall of the canal of the facial nerve, cholesteatoma of the hypothympanum, cholesteatoma in the place of destruction of the bone wall of the posterior cranial fossa. The key reasons for the formation of recurrent pathology were: children under 15 years of age, closed surgery, pathological changes in the tympanic orifice of the auditory tube and the presence of cholesteatoma in its lumen. Performing a closed operation in adults with pathology of the tympanic orifice of the auditory tube increases the risk of recurrent cholesteatoma by 18.6%, and in children by 20%. The choice of a closed method of surgical intervention for the epitympanic type of the disease can increase the risk of residual pathology by 17.2% in adults and 27.8% in children.

[Clinical case for removal infralabyrinthine petrous bone cholesteatoma with preservation the facial nerve]. / Udalenie infralabirintnoi kholesteatomy piramidy visochnoi kosti s sokhraneniem funktsii litsevogo nerva.

The article presents the case report of infralabyrinthine petrous bone cholesteatoma. We have analyzed the preoperative examination of the patient for identification method of surgical treatment with preservation the facial nerve and reducing cholesteatoma risk, perioperative findings and the end result of surgical treatment.

[The peculiar clinical features of different types of acquired cholesteatoma of the middle ear]. / Klinicheskie osobennosti priobretennoi kholesteatomy srednego ukha.

We have undertaken the analysis of the specific clinical manifestations of acquired cholesteatoma of the middle ear in 437 chronic patients suffering from this pathology. 96.1% of them presented with primarily acquired cholesteatoma of the middle ear (including 53.3% having attic cholesteatoma, 22.8% with sinus cholesteatoma, and 19.9% of tensa retraction cholesteatoma). 3.9% of the patients exhibited a different mechanism of development of cholesteatoma. The secondary acquired mesotympanic cholesteatoma formed in association with the long-term chronic inflammation of the middle ear, concomitant perforation of the tympanic membrane and epithelial invasion from the edge of the tympanic membrane perforation and middle ear cavity. Typmanosclerosis of different degree and localization played an important role in the enhancement of the prevalence of this condition. All types of acquired cholesteatoma were found to extend beyond the point of origin of the disorder. The maximum destruction of the ossicular chain was documented in the patients presenting with sinus cholesteatoma. Those with secondary acquired cholesteatoma showed the worst functional capacity as a result of rigid fixation of the auditory ossicles. The overall cholesteatoma relapse rate (including both residual and recurrent cholesteatoma) was estimated to be 15.6%. It is concluded that the surgical strategy should be chosen on an individual basis for each concrete patient. The long-term observation of the treated patients with the application of the up-to-date radiological techniques is believed to be the indispensable prerequisite for the successful management of the complicated pathology under consideration.

[Sanation of petrous bone cholesteatoma in the otosurgical practice]. / Sanatsiia kholesteatomy piramidy visochnoi kosti v otokhirurgicheskoi praktike.

The present article reports the clinical cases of the surgical intervention on 20 patients presenting with petrous bone cholesteatoma. We have identified several clinical variants of petrous bone cholesteatoma based on the results of multispiral computed tomography (MSCT) of the temporal bones and categorized them into the following types in accordance with the classification proposed by Moffat-Smith an M. Sanna for this pathological condition: supralabyrinthine (n=8), supralabyrinthine-apical (n=2), infralabyrinthine (n=3), infralabyrinthine-apical (n=5), massive (n=1), and massive - apical (n=1). The surgical sanation of petrous bone cholesteatoma was performed in all the 20 patients in the absence of the pronounced bone destruction in the walls of the temporal bone pyramid and of the subdural expansion of cholesteatoma. In all the cases, the trepanation cavity remained open till its complete epidermization. The follow up period was around 3 years in duration on the average. The post-surgical analysis of the clinical conditions of each of the 20 patients was performed with special reference to the surgical technique applied for the removal of petrous bone cholesteatoma and the final outcome of the radical treatment.

[The methods of surgical sanation of the difficult to access parts of the middle ear in the patients presenting with chronic suppurative otitis media and concomitant cholesteatoma]. / Sposoby khirurgicheskoi sanatsii trudnodostupnykh otdelov srednego ukha u bol'nykh khronicheskim gnoinym srednim otitom s kholesteatomoi.

The recurrent cholesteatomic process is one of the main causes of the poor outcome of the surgical treatment in the patients with acquired cholesteatoma of the middle ear. The relapse can be due to the incomplete removal of the cholesteatomic matrix especially from the difficult to access for visual control during the surgical intervention parts of the anterior epitympanic space, medial sinuses of retrotympanum, deep-lying portions of hypotympanum, and retrofacial part of the mastoid cavity. One more cause behind the recurrent process is the retention of the conditions for the secondary retraction of the neotympanic membrane, The objective of the present study was the improvement of the surgical modalities for better visualization and sanation of the difficult to access anatomically complex parts of the middle ear under the eye control, the creation of the conditions for the additional ventilation of the tympanic cavity and the reduction of the risk of development of residual and/or recurrent cholesteatomas. To this effect, we undertook the analysis of the results of 438 primary and 226 secondary (revisional) surgical interventions on the patients presenting with chronic suppurative otitis media and concomitant cholesteatomas. The study has demonstrated that the cause of 14.6% of the cases of residual cholesteatoma was the incomplete removal of its matrix from the anterior epitympanic space, medial sinuses of retrotympanum, deep-lying portions of hypotympanum, and retrofacial part of the mastoid cavity. The proposed surgical strategies reduced the risk of development of residual cholesteatoma from 8.2% to 3.9%. The newly developed method for the additional ventilation of the tympanic cavity allowed the frequency of recurrent cholesteatoma to be decreased from 2.5% to 1.6%.