A deep learning model based on magnifying endoscopy with narrow-band imaging to evaluate intestinal metaplasia grading and OLGIM staging: A multicenter study.

BACKGROUND AND PURPOSE: Patients with stage III or IV of operative link for gastric intestinal metaplasia assessment (OLGIM) are at a higher risk of gastric cancer (GC). We aimed to construct a deep learning (DL) model based on magnifying endoscopy with narrow-band imaging (ME-NBI) to evaluate OLGIM staging. METHODS: This study included 4473 ME-NBI images obtained from 803 patients at three endoscopy centres. The endoscopic expert marked intestinal metaplasia (IM) regions on endoscopic images of the target biopsy sites. Faster Region-Convolutional Neural Network model was used to grade IM lesions and predict OLGIM staging. RESULTS: The diagnostic performance of the model for IM grading in internal and external validation sets, as measured by the area under the curve (AUC), was 0.872 and 0.803, respectively. The accuracy of this model in predicting the high-risk stage of OLGIM was 84.0%, which was not statistically different from that of three junior (71.3%, p = 0.148) and three senior endoscopists (75.3%, p = 0.317) specially trained in endoscopic images corresponding to pathological IM grade, but higher than that of three untrained junior endoscopists (64.0%, p = 0.023). CONCLUSION: This DL model can assist endoscopists in predicting OLGIM staging using ME-NBI without biopsy, thereby facilitating screening high-risk patients for GC.

Diagnosis and segmentation effect of the ME-NBI-based deep learning model on gastric neoplasms in patients with suspected superficial lesions - a multicenter study.

Background: Endoscopically visible gastric neoplastic lesions (GNLs), including early gastric cancer and intraepithelial neoplasia, should be accurately diagnosed and promptly treated. However, a high rate of missed diagnosis of GNLs contributes to the potential risk of the progression of gastric cancer. The aim of this study was to develop a deep learning-based computer-aided diagnosis (CAD) system for the diagnosis and segmentation of GNLs under magnifying endoscopy with narrow-band imaging (ME-NBI) in patients with suspected superficial lesions. Methods: ME-NBI images of patients with GNLs in two centers were retrospectively analysed. Two convolutional neural network (CNN) modules were developed and trained on these images. CNN1 was trained to diagnose GNLs, and CNN2 was trained for segmentation. An additional internal test set and an external test set from another center were used to evaluate the diagnosis and segmentation performance. Results: CNN1 showed a diagnostic performance with an accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of 90.8%, 92.5%, 89.0%, 89.4% and 92.2%, respectively, and an area under the curve (AUC) of 0.928 in the internal test set. With CNN1 assistance, all endoscopists had a higher accuracy than for an independent diagnosis. The average intersection over union (IOU) between CNN2 and the ground truth was 0.5837, with a precision, recall and the Dice coefficient of 0.776, 0.983 and 0.867, respectively. Conclusions: This CAD system can be used as an auxiliary tool to diagnose and segment GNLs, assisting endoscopists in more accurately diagnosing GNLs and delineating their extent to improve the positive rate of lesion biopsy and ensure the integrity of endoscopic resection.

APD optimal bias voltage compensation method based on machine learning.

The signal-to-noise ratio (SNR) of avalanche photodiode (APD) in optical detection system is greatly influenced by background radiation and operating temperature, so an APD optimal bias voltage compensation method based on machine learning is designed to accurately judge the current laser emission state and APD working state so that dichotomy compensation can be carried out to make APD work in optimal state. By means of cross-verification, the accuracy of judging laser emission state and APD working state is as high as 100% and 99.3% separately, then the number of input variables in the model is reduced appropriately by experiment and the prediction speed of the algorithm is further improved. Finally, road detection application is taken as the experimental background and comparison between the proposed method and the most widely used signal amplitude feedback compensation method is carried out. The results of this study suggest that the proposed APD optimal bias voltage compensation method based on machine learning offers a new and promising approach.

SAW Torque Sensor Gyroscopic Effect Compensation by Least Squares Support Vector Machine Algorithm Based on Chaos Estimation of Distributed Algorithm.

As this study examined the issue of surface acoustic wave (SAW) torque sensor which interfered in high rotational speed, the gyroscopic effect generated by rotation was analyzed. Firstly, the SAW coupled equations which contained torque and rotation loads were deduced, and the torque calculation error caused by rotation was solved. Following this, the hardware of the SAW gyroscopic effect testing platform and the turntable experiment were designed to verify the correctness of the theoretical calculation. Finally, according to the experimental data, the gyroscopic effect was compensated by multivariate polynomial fitting (MPF), Gaussian processes regression (GPR), and least squares support vector machine algorithms (LSSVM). The comparison results showed that the LSSVM has the obvious advantage. For improving the function of LSSVM model, chaos estimation of distributed algorithm (CEDA) was proposed to optimize the super parameters of the LSSVM, and numerical simulation results showed that: (1) CEDA is superior to traditional estimation of distributed algorithms in convergence speed and anti-premature ability; (2) the performance of CEDA-LSSVM is better than genetic algorithms (GA)-LSSVM and particle swarm optimization (PSO)-LSSVM. After compensating by CEDA-LSSVM, the magnitude of the torque calculation relative error was 10-4 in any direction. This method has a significant effect on reducing gyroscopic interference, and it lays a foundation for the engineering application of SAW torque sensor.