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1.
Diagn Interv Radiol ; 24(5): 308-315, 2018 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30211684

RESUMO

METHODS: A total of 20 heparinized pig kidneys were investigated at 10 intrapelvic hydrostatic pressure steps (0-90 mmHg). SWE (ARFI; Virtual TouchTM IQ, Siemens) measurements were taken at three different measuring regions and in two measuring sequences using a linear ultrasonography probe (9L4, Siemens). Median values of 10 shear-wave speed (SWS) measurements were calculated for each pressure step. Logarithmic transformed median SWS values were analyzed in a linear mixed model. RESULTS: SWS increased significantly with increasing intrapelvic pressure. Median SWS for all kidneys in both measuring sequences and all measuring regions was 1.47 m/s (interquartile range [IQR], 0.38 m/s) at 0 mmHg, 1.94 m/s (IQR, 0.42 m/s) at 30 mmHg, 2.07 m/s (IQR, 0.43 m/s) at 60 mmHg, 2.24 m/s (IQR, 0.49 m/s) at 90 mmHg. The correlation between pelvic pressure increase and median SWS values for the central parenchyma was significantly higher compared with the peripheral parenchyma. CONCLUSION: Acutely increased renal pelvic pressure correlates with increasing SWS values in ARFI elastography in an ex vivo porcine kidney model.


Assuntos
Técnicas de Imagem por Elasticidade/métodos , Rim/anatomia & histologia , Tecido Parenquimatoso/diagnóstico por imagem , Sistema Urinário/patologia , Animais , Rim/diagnóstico por imagem , Rim/fisiopatologia , Modelos Animais , Tecido Parenquimatoso/fisiopatologia , Pelve/fisiologia , Pressão , Suínos , Ultrassonografia/métodos
2.
Med Ultrason ; 19(4): 366-373, 2017 Nov 29.
Artigo em Inglês | MEDLINE | ID: mdl-29197912

RESUMO

AIMS: To evaluate the applicability of point shear wave elastography (pSWE) for measuring renal parenchymal stiffness in healthy children and adolescents and to establish norm values for shear wave speed (SWS) using two ARFI methods and ultrasound probes. MATERIAL AND METHODS: We prospectively investigated 264 children (43.9% males). pSWE (Virtual TouchTM Quantification and Virtual TouchTM Imaging Quantification (VTQ and VTIQ; Siemens, Germany)) was performed in the renal cortex of 528 healthy kidneys using a 1-6 MHz convex and a 4-9 MHz linear ultrasound probe in ventrolateral and dorsal examinations. Feasibility and reproducibility of pSWE measurements were evaluated. SWS values were analysed with regard to age, body dimensions, kidney volume and measuring depth. RESULTS: pSWE measurements were successful in >95% of subjects using the low and in <60% using the high-frequency probe. Mean SWS values (m/s) differed by method and probe: 2.10±0.43 (VTQ1-6MHz, convex, ventrolateral), 2.30±0.37 (VTQ1-6MHz, convex, dorsal), 1.58±0.44 (VTQ4-9MHz, linear, dorsal) and 1.96±0.27 (VTIQ4-9MHz, linear, dorsal). SWS was positively correlated with age, weight and body height, but independent of sex, BMI, or kidney volume and depth. CONCLUSIONS: pSWE (VTQ) is a feasible method to evaluate renal parenchymal stiffness in children of all ages. SWS values are age and weight dependent and differ significantly between high- and low-frequency probes. High-frequency probes and VTIQ should only be used in children <10 years.


Assuntos
Técnicas de Imagem por Elasticidade/métodos , Rim/anatomia & histologia , Adolescente , Adulto , Criança , Pré-Escolar , Estudos de Viabilidade , Feminino , Humanos , Lactente , Masculino , Estudos Prospectivos , Valores de Referência , Reprodutibilidade dos Testes , Adulto Jovem
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