Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Mais filtros

Base de dados
Ano de publicação
Tipo de documento
Intervalo de ano de publicação
1.
Parkinsonism Relat Disord ; 109: 105360, 2023 04.
Artigo em Inglês | MEDLINE | ID: mdl-36921515

RESUMO

INTRODUCTION: Reliable diagnosis of vascular parkinsonism (VaP) in the presence of a gait hypokinesia is an issue that is encountered in geriatrics. The EVAMAR-AGEX study was focusing on the phenomenon of recurrent falls in older persons (OP) with this parkinsonian gait. The present study is focusing on the diagnosis of VaP-related parkinsonian gait by developing a diagnostic guidance model adapted to OP. METHODS: Data from baseline and the 2-year follow-up visit were used to carry out univariate analysis and calculation of odds ratios, allowing to identify relevant variables to include in the diagnostic guidance model. To evaluate the model, confusion matrices were created, evaluating true positive, false negative, false positive and true negative incidences, sensitivity and specificity, and negative and positive predictive values. RESULTS: 79 patients included 58% male; average age 81.24 years. VaP diagnosis according to Zijlmans criteria occurred in 28%; neurodegenerative parkinsonian syndromes in 72%. A 4-criteria model was established to facilitate diagnostic: lack of prior hallucinations, lack of movement disorders tremor excluded, no cognitive fluctuations, and ≥75 years of age at diagnosis. In combination of 4/4 criteria, all of them were required to disclose a specificity of 91% in the diagnosis of VaP. In combination of 3/4, in case of negative test, a negative predictive value for VaP diagnosis of 0.97 was obtained. CONCLUSION: The challenge of our tool is both to be able to rule out what is probably not a VaP and to argue what makes a VaP diagnosis probable in OP.


Assuntos
Transtornos dos Movimentos , Doença de Parkinson Secundária , Transtornos Parkinsonianos , Doenças Vasculares , Humanos , Masculino , Idoso , Idoso de 80 Anos ou mais , Feminino , Hipocinesia/diagnóstico , Hipocinesia/etiologia , Transtornos Parkinsonianos/complicações , Transtornos Parkinsonianos/diagnóstico , Tremor/epidemiologia , Marcha , Doença de Parkinson Secundária/diagnóstico , Doença de Parkinson Secundária/etiologia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA