Assuntos
Antioxidantes/análise , Doença da Artéria Coronariana/sangue , Doença da Artéria Coronariana/diagnóstico por imagem , Peróxidos Lipídicos/sangue , Adulto , Idoso , Colesterol/sangue , HDL-Colesterol/sangue , LDL-Colesterol/sangue , VLDL-Colesterol/sangue , Angiografia Coronária , Progressão da Doença , Glutationa Peroxidase/sangue , Humanos , Malondialdeído/sangue , Pessoa de Meia-Idade , Valores de Referência , Selênio/sangue , Compostos de Sulfidrila/sangueRESUMO
Erythrocytes from alcoholics without liver cirrhosis and control subjects were examined for the susceptibility to lipid peroxidation. Erythrocytes of patients were found to be sensitive to H2O2-induced peroxidation as compared to controls. In addition, chronic alcoholics showed a high level of plasma lipid peroxide levels. These results suggest the stimulation of lipid peroxidation in chronic alcoholics.
Assuntos
Alcoolismo/sangue , Eritrócitos/metabolismo , Peróxidos Lipídicos/sangue , Adulto , Glutationa/sangue , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
Plasma lipid peroxide levels and the susceptibility of erythrocytes to lipid peroxidation were significantly increased in patients with essential hypertension. Patients with retinopathy had higher lipid peroxide levels compared to those without retinopathy. No change was observed in spontaneous hemolysis test values, an indicator of vitamin E status, and erythrocyte glutathione levels of essential hypertensives compared to normotensives. However, erythrocyte glutathione levels were found to be decreased in patients with retinopathy. These results showed that lipid peroxidation was increased in patients with essential hypertension and that this increase was more pronounced in those with retinopathy.