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1.
Aesthet Surg J ; 44(8): NP532-NP539, 2024 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-38748536

RESUMO

BACKGROUND: Despite the significant roles it plays in the functions of the platysma and lower lip, the cervical branch of the facial nerve is often overlooked compared to other branches, but its consideration is critical for ensuring the safety of neck surgeries. OBJECTIVES: The aim of this study was to clarify the anatomical discrepancies associated with the cervical branch of the facial nerve to enhance surgical safety. METHODS: The study utilized 20 fresh-frozen hemiheads. A 2-stage surgical procedure was employed, beginning with an initial deep-plane facelift including extensive neck dissection, followed by a superficial parotidectomy on fresh-frozen cadavers. This approach allowed for a thorough exploration and mapping of the cervical nerve in relation to its surrounding anatomical structures. RESULTS: Upon exiting the parotid gland, the cervical nerve consistently traveled beneath the investing layer of the deep cervical fascia for a brief distance, traversing the deep fascia to travel within the areolar connective tissue before terminating anteriorly in the platysma muscle. A single branch was observed in 2 cases, while 2 branches were noted in 18 cases. CONCLUSIONS: The cervical nerve's relatively deeper position below the mandible's angle facilitates a safer subplatysmal dissection via a lateral approach for the release of the cervical retaining ligaments. Due to the absence of a protective barrier, the nerve is more susceptible to injuries from direct trauma or thermal damage caused by electrocautery, especially during median approaches.


Assuntos
Cadáver , Nervo Facial , Ritidoplastia , Humanos , Ritidoplastia/métodos , Ritidoplastia/efeitos adversos , Feminino , Nervo Facial/anatomia & histologia , Masculino , Idoso , Pescoço/anatomia & histologia , Pescoço/inervação , Pescoço/cirurgia , Pessoa de Meia-Idade , Esvaziamento Cervical/efeitos adversos , Sistema Musculoaponeurótico Superficial/anatomia & histologia , Sistema Musculoaponeurótico Superficial/cirurgia , Glândula Parótida/anatomia & histologia , Glândula Parótida/cirurgia , Glândula Parótida/inervação , Músculos do Pescoço/inervação , Músculos do Pescoço/anatomia & histologia , Idoso de 80 Anos ou mais
2.
Aesthet Surg J ; 43(8): 805-816, 2023 07 15.
Artigo em Inglês | MEDLINE | ID: mdl-36967478

RESUMO

BACKGROUND: Opening the neck through a submental incision allows accurate management of deep neck structures and results in exceptional neck contours. OBJECTIVES: The authors aimed to evaluate the distribution of deep neck structures and investigate the detailed vascular anatomy of the submandibular gland. METHODS: A total of 26 fresh frozen cadaver heads (15 female, 11 male) were utilized. The authors evaluated the weights of the excised tissues simulating cosmetic resections, including subcutaneous fat, subplatysmal fat, the anterior belly of the digastric muscle, and submandibular glands. The vascular supply of the submandibular gland and intracapsular vessel diameters were also investigated. RESULTS: Whereas female cadavers had greater mean tissue weight removed from the supraplatysmal plane (mean 20.9 g, 56.6%) than the subplatysmal plane (16 g, 43.4%), male cadavers had higher mean tissue weight removed from the subplatysmal plane (10.5 g, 60.7%) than the supraplatysmal plane (mean 6.8 g, 39.3%). The mean subcutaneous (6.8 g) and subplatysmal (6.4 g) fat weights were almost equal in male cadavers; mean subcutaneous fat weight (20.9 g) was 3 times higher than subplatysmal fat weight (6.8 g) in female cadavers. There was a statistically significant relationship between body mass index and fat removed. The intraglandular vessel diameters increased as resections approached the main feeding vessels located posterosuperior (facial artery) and anterosuperior (submental artery) to the submandibular gland. CONCLUSIONS: The results suggest that to achieve exceptional neck contour the structures deep to the platysma often need to be addressed. The submandibular gland reduction can be safely performed with comprehensive understanding of its vascular anatomy.


Assuntos
Procedimentos de Cirurgia Plástica , Glândula Submandibular , Humanos , Masculino , Feminino , Glândula Submandibular/cirurgia , Glândula Submandibular/anatomia & histologia , Pescoço/cirurgia , Músculos do Pescoço/anatomia & histologia , Músculos do Pescoço/cirurgia , Cadáver
3.
Am J Otolaryngol ; 41(6): 102712, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32942114

RESUMO

PURPOSE: The present study compares the local anesthetic efficacy of EMLA® cream and lidocaine injection used in the radiofrequency reduction of the inferior turbinate. METHODS: The study included a total of 124 patients with inferior turbinate hypertrophy and who underwent turbinate reduction under local anesthesia. The operations were performed 15 min after a lidocaine injection and 30 min after EMLA cream application. The respondent patients were asked to interpret such situations as intraoperative pain, discomfort during the procedure, choking sensation and difficulty swallowing using the Visual Analogue Scale (VAS). RESULTS: The EMLA cream patients (Group A) were found to have a lower level of discomfort, choking sensation and difficulty swallowing than the lidocaine patients (Group B), while there was no substantial difference in pain between the two groups. CONCLUSIONS: It is concluded that EMLA® cream is an effective alternative to lidocaine injection during inferior turbinate reduction procedures.


Assuntos
Anestesia Local/métodos , Anestésicos Locais/administração & dosagem , Combinação Lidocaína e Prilocaína/administração & dosagem , Lidocaína/administração & dosagem , Lidocaína/efeitos adversos , Conchas Nasais/cirurgia , Adulto , Anestésicos Locais/efeitos adversos , Feminino , Humanos , Hipertrofia/cirurgia , Injeções , Combinação Lidocaína e Prilocaína/efeitos adversos , Masculino , Procedimentos Cirúrgicos Otorrinolaringológicos/métodos , Ablação por Radiofrequência , Estudos Retrospectivos , Conchas Nasais/patologia , Adulto Jovem
4.
Aesthetic Plast Surg ; 44(5): 1759-1765, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32700009

RESUMO

BACKGROUND: Following open rhinoplasty, a postoperative scar at the columellar incision line is a common morbidity. The aim of this study is to compare absorbable and nonabsorbable suture materials which had been used for closing the transcolumellar incision, in the aspect of risk of postoperative infection, wound healing, postoperative columellar scar and patient satisfaction. METHOD: A prospective, randomized, single-blind study was conducted between May 2017 and February 2018. Sixty-four rhinoplasty patients were randomly assigned to absorbable (n = 32) or nonabsorbable (n = 32) groups. The columellar incision was closed with 7 full-thickness skin sutures. Either nonabsorbable 6/0 polypropylene (Group 1) or absorbable 6/0 polyglytone 6211 (Group 2) sutures were placed at the columellar incisions. Polypropylene sutures were removed at the 7th postoperative day. A Mann-Whitney U test and Monte Carlo were used for statistical comparison. Photographs of the patients at the postoperative third month (Fig. 2) were evaluated and scored in terms of scarring, pigmentation, notching, level differences in the incision area by two different otorhinolaryngologists who did not know the randomization. Suture removing discomfort was assessed with visual analogue scale scores. A satisfaction survey was filled out by all the patients completing their third month after the operation. RESULTS: According to the results of both otorhinolaryngologists, there was no significant difference between the two groups in terms of pigmentation, level difference, notching, overall appearance and total score (p = 0.920, p = 0.498, respectively). The mean score on the Wong-Baker scale was 3.19 ± 1.67 in group 1. In the Satisfaction Survey, the average score of the group 1 was 6.90 ± 3.24, while the mean score of the group 2 was 7.062 ± 2.77. There was no statistically significant difference between the two groups (p = 0.715). CONCLUSIONS: Suturing inverted V transcolumellar incisions with rapid resorbable sutures caused significantly less discomfort but no difference in scarring compared to nonresorbable sutures as evaluated by patients and observers. LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .


Assuntos
Rinoplastia , Técnicas de Sutura , Humanos , Septo Nasal/cirurgia , Estudos Prospectivos , Método Simples-Cego , Suturas , Resultado do Tratamento
5.
Aesthetic Plast Surg ; 44(5): 1718-1724, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32458043

RESUMO

BACKGROUND: Rhinoplasty is one of the most unforgiving operations in facial plastic surgery. The correction of nasal deviation in an asymmetrical face can be challenging because known facial landmarks may mislead the surgeon. Eyebrows trimmed asymmetrically in an effort to create a more symmetrical facial appearance may be overlooked by surgeons. OBJECTIVE: To define the relationship between the eyebrow position and external nasal deviation in patients with a crooked nose. DESIGN, SETTING, AND PARTICIPANTS: Analysis was made of the preoperative and 6-month postoperative life-size photographs of female rhinoplasty patients who had been referred to the senior author's clinic between May 2014 and June 2019. The anthropometric landmarks on the life-size photographs were identifed. The most medial points of the eyebrows and most deviated part of the nose were marked and the distance from the mid-canthal point was measured. MAIN OUTCOMES AND MEASURE: The direction and amount of eyebrow shift were compared with the direction and amount of nasal deviation. RESULTS: Of the total 94 female rhinoplasty patients with at least one level external nasal deviation, 67 (71.2%) had ipsilateral eyebrow shift with external nasal deviation. The preoperative external nasal deviation amount was 1.81 ± 1.21 mm and preoperative eyebrow shift was 1.18 ± 1.06 mm (rS = 0.429, p < 0.001). The postoperative nasal deviation was 0.79 ± 0.92 mm, and the eyebrow shift was 0.54 ± 0.62 mm (rS = 0.570, p < 0.001). CONCLUSION AND RELEVANCE: Patients may tend to trim their eyebrows towards the side of the external nasal deviation. After centralization of the crooked nose with rhinoplasty, asymmetric eyebrow shaping tendencies of the patients were also seen to be improved. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .


Assuntos
Deformidades Adquiridas Nasais , Rinoplastia , Estética , Sobrancelhas , Feminino , Humanos , Septo Nasal/cirurgia , Nariz/cirurgia , Deformidades Adquiridas Nasais/cirurgia , Resultado do Tratamento
6.
Aesthetic Plast Surg ; 44(3): 910-916, 2020 06.
Artigo em Inglês | MEDLINE | ID: mdl-31834522

RESUMO

BACKGROUND: The age at which nasal tip support changes start to occur is unknown. Evaluation of nasal tip support is difficult, especially as the ideal nasal tip support pressure remains elusive. The aim of this study is to determine the nasal tip support pressure alterations relative to age and sex. OBJECTIVES: The aim of this study is to determine the changers in resistance of the nasal tip support in relation to age and sex. METHODS: This prospective clinical study was conducted between January and April 2019 at a tertiary health facility. Nasal tip resistances were measured in four different age-groups (20-29, 30-39, 40-64, and > 65 years) with a digital Newton meter. A total of 159 patients with a minimum of 36 patients per group were included in the study. Nasal tip resistance measurements were compared among nasal tip displacement distances of 2, 3, and 4 mm, focusing on age and sex. RESULTS: The nasal tip resistance of the 20-29 age-group was significantly higher at 2, 3, and 4 mm nasal tip displacement distances, when compared with the 30-39 and 40-64 age-groups, whereas compared to the > 65 years group, it was significantly higher at 3 and 4 mm nasal tip displacement distances (p < 0.005). Nasal tip resistance of males was found to be significantly higher than that of females, at 3 and 4 mm nasal tip displacement distances (p < 0.001). CONCLUSIONS: Nasal tip resistance is higher in males and universally decreases significantly after 30 years of age while remaining constant at later ages. Therefore, surgeons should prefer nasal tip resistance increasing techniques in the rhinoplasty operations that are performed on patients even from early years of age, in order to maintain and strengthen the nasal tip resistance. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.


Assuntos
Septo Nasal , Rinoplastia , Adulto , Estética , Feminino , Seguimentos , Humanos , Masculino , Septo Nasal/cirurgia , Estudos Prospectivos , Resultado do Tratamento
7.
Aesthetic Plast Surg ; 43(4): 1021-1027, 2019 08.
Artigo em Inglês | MEDLINE | ID: mdl-30895358

RESUMO

BACKGROUND: A good understanding of nasal tip support mechanisms is essential for achieving successful and functional rhinoplasty results. The loss of nasal tip support resulting from different maneuvers adopted during rhinoplasty and how this loss is affected by reconstructive applications should be known. This study evaluated and compared changes in nasal tip support perioperatively after different techniques were used during septorhinoplasty. METHODS: Patients who underwent primary open rhinoplasty between January 2018 and March 2018 in a tertiary medical center were included in this prospective blind case series. Nasal tip resistance measurements were taken after perioperative maneuvers by creating enough force to achieve 1 mm, 2 mm and 3 mm of displacement at the tip region. Measurements were obtained during six different stages using a Newton meter: preoperatively, after caudal septal resection, after skin flap elevation, after the columellar strut or tongue-in-groove procedure, after tip suturing and postoperatively. Our hypothesis was that during septorhinoplasty, each maneuver used changes the tip support intraoperatively. The predictor variables were the different rhinoplasty techniques used. The outcome variable was nasal tip resistance to compression intraoperatively and immediate postoperatively. Appropriate statistics were computed, and a p < 0.05 value was considered significant. RESULTS: Ten of the 15 patients were female, and 5 were male. The patient age ranged from 19 to 40 (mean 24.8 ± 4.9). The tongue-in-groove technique was applied in 5 of the patients, while columellar strut grafting was performed in 10. The application of columellar strut grafting did not create a significant increase in nasal tip support (p > 0.05). An increase in nasal tip support was observed at each stage (85%, 53%, 35%) after application of the tongue-in-groove technique (p < 0.05). CONCLUSIONS: A novel and reproducible technique for digitally evaluating manual force is presented for determining changes in nasal tip support with different maneuvers applied in living patients undergoing rhinoplasty. No significant difference was noted between the preoperative and postoperative measurements for columellar strut grafting. The tongue-in-groove technique is an important maneuver that has a significant effect on nasal tip support. According to our data, the interdomal and intercrural ligaments, the medial crus-septum connections and the connections between alar cartilage and overlying skin and muscle tissue are important structures for tip support. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .


Assuntos
Cartilagens Nasais/cirurgia , Septo Nasal/cirurgia , Nariz/cirurgia , Rinoplastia/métodos , Retalhos Cirúrgicos/transplante , Cicatrização/fisiologia , Adulto , Fatores Etários , Estudos de Coortes , Estética , Feminino , Seguimentos , Hospitais Universitários , Humanos , Masculino , Septo Nasal/fisiopatologia , Nariz/anatomia & histologia , Estudos Prospectivos , Medição de Risco , Fatores Sexuais , Fatores de Tempo , Resultado do Tratamento , Turquia , Adulto Jovem
8.
Exp Clin Transplant ; 2018 Sep 04.
Artigo em Inglês | MEDLINE | ID: mdl-30198839

RESUMO

OBJECTIVES: The aim of this study was to define the otorhinolaryngologic manifestations and clinical characteristics of patients who received kidney or liver transplants at a university hospital. MATERIALS AND METHODS: Medical records of patients who received a kidney or liver transplant between 2000 and 2013 and who were referred or applied to the ear, nose, and throat clinic were retrospectively reviewed. Otorhinolaryngologic complaints, signs, examination findings, and diagnoses of patients were noted. RESULTS: Our analyses included 540 visits to the ear, nose, and throat clinic by 101 liver and 191 kidney transplant recipients. Mean duration between date of transplant and otorhinolaryngologic examination was 747.9 ± 37.1 days. The most common complaint was rhinorrhea (n = 112), whereas the most common diagnosis was acute rhinosinusitis (n = 85). Acute upper respiratory tract infections, including rhinosinusitis, were diagnosed more frequently during the late postoperative period (ie, > 180 days after transplant). Epistaxis was more frequent during the first 30 days after transplant. CONCLUSIONS: A diverse variety of otorhinolaryngologic conditions, including emergencies and potentially life-threatening infections, were seen in our kidney and liver transplant recipients, both during the early and the late follow-up period. All transplant team members should be familiar with the clinical presentation of frequently seen otorhinolaryngologic diseases.

9.
Kulak Burun Bogaz Ihtis Derg ; 26(3): 152-8, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27107601

RESUMO

OBJECTIVES: This study aims to compare pain, bleeding, nasal obstruction, crust and synechia formation, and anesthesia-related morbidity in patients with and without use of nasal packs after septoplasty. PATIENTS AND METHODS: A total of 66 patients (32 women, 34 men; mean age 24 years; range 18 to 48 years) who underwent Cottle's septoplasty under general anesthesia were randomly allocated to three groups in this prospective cohort. Telfa nasal packs were used in sutures + telfa group (n=22) and Merocell nasal packs in merocel alone group (n=22). No packs were administered in sutures alone group (n=22). Three groups were compared in terms of nasal obstruction, bleeding, pain, crust and synechia formation, as well as the amount of secretion, the need for oropharyngeal airway, the presence of laryngospasm, and effort for nasal breathing after anesthesia. RESULTS: The amount of bleeding was higher with lower degree of nasal obstruction in sutures alone group. Pain and secretion were more remarkable in merocel alone group. After the first week, these differences were unable to be differentiated among the groups. There were no differences between three groups with respect to crust and synechia formation two weeks after septal surgery. CONCLUSION: Nasal packs can be more useful in patients who suffer from bleeding-related morbidity, while septoplasty applied without nasal packs can be more suitable in patients with obstructive sleep apnea. The use of nasal packs in septoplasty should be determined on an individualized basis with respect to the characteristics of each patient.


Assuntos
Rinoplastia/métodos , Tampões Cirúrgicos , Adolescente , Adulto , Bandagens , Epistaxe/etiologia , Feminino , Formaldeído , Humanos , Masculino , Pessoa de Meia-Idade , Obstrução Nasal/etiologia , Septo Nasal/cirurgia , Medição da Dor , Conforto do Paciente , Álcool de Polivinil , Estudos Prospectivos , Aderências Teciduais/etiologia , Adulto Jovem
10.
Kulak Burun Bogaz Ihtis Derg ; 26(1): 12-8, 2016.
Artigo em Turco | MEDLINE | ID: mdl-26794330

RESUMO

OBJECTIVES: This study aims to investigate the possible relationship between passive rhinomanometry measurements in sitting and supine position and obstructive sleep apnea syndrome. PATIENTS AND METHODS: Between January 2011 and December 2013, 88 male patients (mean age 46.8 years; range 18 to 79 years) underwent passive rhinomanometry in sitting and supine position following history, physical examination and fiberoptic endoscopic examination. 1.5 lt/sn air flow was pumped into the nose of each patient via a silicone nasal mask. Meanwhile, flow and pressure values were measured. RESULTS: There was no correlation between the resistance values and apnea hypopnea index (AHI) scores and polysomnography and physical examination parameters (p>0.05). The differential resistance was correlated with AHI (r=0.325, p<0.05), body mass index (r=0.324, p<0.05), neck circumference (r=0.421, p<0.01), waist circumference (r=0.444, p<0.01), modified Mallampati score (r=0.356, p<0.05), and retropalatal grade (r=0.438, p<0.01). CONCLUSION: The correlation between the differential resistance and physical examination parameters and AHI scores support the hypothesis that position-related retropalatal segment alterations can be measured by passive rhinomanometry while awake.


Assuntos
Rinomanometria/métodos , Apneia Obstrutiva do Sono/diagnóstico , Decúbito Dorsal , Adolescente , Adulto , Idoso , Índice de Massa Corporal , Humanos , Masculino , Pessoa de Meia-Idade , Pescoço/anatomia & histologia , Exame Físico , Polissonografia , Circunferência da Cintura , Adulto Jovem
11.
J Craniofac Surg ; 26(3): e244-6, 2015 May.
Artigo em Inglês | MEDLINE | ID: mdl-25915667

RESUMO

Endoscopic approaches have become an alternative to external approaches in the treatment of sinonasal inverted papillomas (IPs) in recent years. The aim of this study was to analyze the outcomes of endoscopic modified medial maxillectomy preserving the nasolacrimal duct and the inferior turbinate in selected IP cases. Medical charts of patients diagnosed with IP originating from the maxillary sinus between July 2008 and August 2013 were reviewed. Eight patients who had undergone endoscopic modified medial maxillectomy were included in the study. Attachment of IP was located on the medial wall of the maxillary sinus in all cases. The nasolacrimal duct was preserved in all of the patients. The inferior turbinate was completely preserved in 5 patients, and the anterior part of the inferior turbinate was preserved in 3 patients. The mean follow-up period of the patients was 30.8 months (12-60  mo). None of the patients had recurrence or major complications. The postoperative complaints were minor hemorrhagic discharge and crusting for the first few weeks. Endoscopic modified medial maxillectomy preserving the nasolacrimal duct and the inferior turbinate provides good surgical and functional outcomes in selected IP cases.


Assuntos
Endoscopia/métodos , Osteotomia Maxilar/métodos , Neoplasias do Seio Maxilar/cirurgia , Seio Maxilar/cirurgia , Papiloma Invertido/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
12.
Laryngoscope ; 125(6): 1291-5, 2015 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-25476595

RESUMO

OBJECTIVES/HYPOTHESIS: Septorhinoplasty is one of the most commonly performed plastic surgery procedures in the world. Studies on septorhinoplasty in the literature mainly focus on the surgical procedures and their outcomes, but the general appearance of the nose and nasal skin following surgery is also very important. STUDY DESIGN: Case-control study examining 30 septorhinoplasty patients and 20 septoplasty patients for postoperative skin conditions. RESULTS: There were significant differences identified between the septorhinoplasty group and the septoplasty group with respect to their mean preoperative Global Acne Grading System, Seborrheic Dermatitis Area Severity Index, and visual analog scores (acne, seborrhea, and ecchymosis). CONCLUSIONS: The aim of study was to identify and evaluate postoperative skin conditions among septorhinoplasty patients, as well as the progression and duration of treatment of these conditions. LEVEL OF EVIDENCE: 3b.


Assuntos
Acne Vulgar/epidemiologia , Acne Vulgar/etiologia , Dermatite Seborreica/epidemiologia , Dermatite Seborreica/etiologia , Equimose/epidemiologia , Equimose/etiologia , Septo Nasal/cirurgia , Rinoplastia/efeitos adversos , Adolescente , Adulto , Estudos de Casos e Controles , Feminino , Humanos , Masculino , Adulto Jovem
13.
Laryngoscope ; 124(11): E425-30, 2014 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-24966072

RESUMO

OBJECTIVES/HYPOTHESIS: To show and compare the long-term inflammatory responses to subdermal microdroplet injections of 1,000 centistoke (cS) and 5,000 cS liquid injectable silicone (LIS), and to assess the applicability of insulin pen as an alternative LIS delivery device in an animal model. STUDY DESIGN: Animal study. METHODS: Eighteen healthy adult Sprague-Dawley rats were used. Two graft recipient sites and four injection sites were prepared on each rat's back for: 1) autogenous auricular cartilage graft; 2) silicone sheet; 3) 1,000 cS LIS injection with insulin syringe; 4) 1,000 cS LIS injection with insulin pen; 5) 5,000 cS LIS injection with insulin syringe; and 6) 5,000 cS LIS injection with insulin pen. The animals were followed up for 6 months, and skin biopsies were examined for the evaluation of LIS microdroplets in situ and the degree of inflammatory tissue response. Immunohistochemistry was used for the examination of macrophages and the density of microvessels. RESULTS: Biopsies from 17 animals were assessed. There was no statistically significant difference among the groups in terms of the number of lymphocytes (P = 0.081), macrophages (P = 0.857), and neutrophils (P = 0.995), the degree of vascular proliferation (P = 0.698), and the mean LIS microdroplet diameter (P = 0.540). Grossly, there was no sign of granuloma formation in any of the specimens. CONCLUSION: There is a low-grade, well-tolerated long-term inflammatory response to microdroplet injections of 1,000 cS and 5,000 cS LIS that is comparable to autogenous cartilage graft in rats. Standard dose delivery devices such as insulin pens can be used for controlled LIS injections. LEVEL OF EVIDENCE: N/A.


Assuntos
Cartilagem Articular/cirurgia , Inflamação/patologia , Silicones/farmacologia , Pele/patologia , Animais , Biópsia por Agulha , Modelos Animais de Doenças , Injeções Subcutâneas , Contagem de Linfócitos , Macrófagos/citologia , Masculino , Neutrófilos/citologia , Tamanho da Partícula , Distribuição Aleatória , Ratos , Ratos Sprague-Dawley , Rinoplastia/métodos , Ritidoplastia/métodos , Sensibilidade e Especificidade , Seringas , Fatores de Tempo , Transplante Autólogo
14.
Plast Reconstr Surg ; 128(5): 1045-1051, 2011 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-22030487

RESUMO

BACKGROUND: Cartilage grafts are frequently used in nasal surgery for structural and/or aesthetic purposes. The literature holds contradictory reports concerning the effect of crushing on the viability of cartilage grafts. METHODS: Nasal septal and costal cartilage grafts were harvested from 12 New Zealand rabbits. Each nasal septal and costal cartilage was divided into five equal pieces. One of the pieces was left intact and the remaining four were prepared as slightly, moderately, severely, or significantly crushed. The cartilage pieces were then autoimplanted into the paravertebral skin of the rabbits. The animals were euthanized 4 months later and the effect of crushing on cartilage grafts was assessed pathologically. RESULTS: The viability of the chondrocytes was found to be decreased as the level of crushing increased. The mean chondrocyte viability rates for the intact, slightly crushed, moderately crushed, severely crushed, and significantly crushed cartilages were 88, 75, 51, 41, and 13 percent for the septal cartilages and 94, 83, 62, 32, and 26 percent for the costal cartilages, respectively. The differences between the mean viability rates of septal and costal cartilage groups were statistically not significant. CONCLUSIONS: The level of crushing determines the rate of viability for the crushed cartilage. Viability rates and the clinical properties of the slightly crushed cartilage grafts at long-term follow-up may be similar to those of the intact cartilage grafts. However, severe or significant crushing leads to a decrement in the viability of the chondrocytes and may cause unpredictable degrees of volume loss at long-term follow-up.


Assuntos
Transplante de Células/métodos , Condrócitos/transplante , Cartilagens Nasais/transplante , Sobrevivência de Tecidos/fisiologia , Animais , Modelos Animais de Doenças , Rejeição de Enxerto , Sobrevivência de Enxerto , Cartilagens Nasais/citologia , Coelhos , Distribuição Aleatória , Costelas/citologia , Costelas/transplante , Sensibilidade e Especificidade , Estatísticas não Paramétricas , Coleta de Tecidos e Órgãos/métodos
15.
Otolaryngol Head Neck Surg ; 145(2): 319-23, 2011 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-21493269

RESUMO

OBJECTIVE: To investigate the clinical features of paranasal sinus osteomas and to estimate the growth rate of these tumors in a large series of patients. DESIGN: Case series with chart review. SETTING: University hospital, tertiary referral center. SUBJECTS AND METHODS: The authors retrospectively reviewed the paranasal sinus tomography scans that were taken between January 1997 and April 2008 to find patients with paranasal sinus osteomas. A questionnaire was performed to evaluate the possible clinical symptoms associated with sinus osteomas, and control paranasal sinus computed tomography was taken for patients in whom paranasal computed tomography examination had been done at least 1 year ago. RESULTS: A total of 17,154 paranasal sinus computed tomographies of 14,137 patients were reviewed, and 243 cases of paranasal sinus osteomas were found. The lesions were located in the frontal sinus in 183, ethmoid sinus in 48, maxillary sinus in 5, and sphenoid sinus in 7 patients. Eighty-nine patients with paranasal sinus osteomas were readmitted. The mean follow-up was 54 months in this group. In 46 of 89 patients, an increase in the size of osteomas was detected. The mean growth rate of osteomas was estimated to be 0.79 mm/y in the cephalocaudal direction and 0.99 mm/y in the mediolateral direction. No significant differences were found in the growth rate according to location and growth directions. CONCLUSION: Neither a specific growth pattern nor a specific factor affecting the growth rate of these tumors could be demonstrated. Follow-up is necessary because of the potential severe complications.


Assuntos
Neoplasias Ósseas/diagnóstico por imagem , Osteoma/diagnóstico por imagem , Neoplasias dos Seios Paranasais/diagnóstico por imagem , Seios Paranasais , Tomografia Computadorizada por Raios X , Adolescente , Adulto , Idoso , Progressão da Doença , Feminino , Seguimentos , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Recidiva Local de Neoplasia/diagnóstico por imagem , Recidiva Local de Neoplasia/epidemiologia , Estudos Retrospectivos , Índice de Gravidade de Doença , Inquéritos e Questionários , Turquia/epidemiologia , Adulto Jovem
16.
J Craniomaxillofac Surg ; 39(3): 221-5, 2011 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-20418106

RESUMO

The amount or quality of available septal cartilage may be inadequate for grafting in some rhinoplasty patients. In such cases, auricular or costal cartilage may provide an additional source of cartilage. Crushed septal cartilage has been shown to be useful for dorsal onlay grafts. We aimed to investigate the effect of different degrees of crushing on the viability of human auricular and costal cartilage. Ten auricular and 10 costal cartilage grafts were obtained from 20 patients during secondary rhinoplasty. Each graft was sectioned into five pieces. One of the pieces was left intact and the remaining four were prepared as slightly, moderately, significantly, and severely crushed. Viability and proliferation rates of chondrocytes in cell cultures were evaluated. Mean viability rates on day 1 for intact, slightly crushed, moderately crushed, significantly crushed, and severely crushed auricular cartilages were 70%, 67%, 65%, 58%, and 45%; while those for costal cartilages were 65%, 63%, 59%, 55%, and 53%, respectively. There was no statistically significant difference between the viability rates of the similarly crushed auricular and costal cartilage groups on days 1, 2, 3 and 10. The viability of crushed human auricular and costal cartilage grafts depends on the degree of crushing applied.


Assuntos
Condrócitos/citologia , Condrócitos/fisiologia , Adulto , Sobrevivência Celular , Células Cultivadas , Condrócitos/transplante , Cartilagem da Orelha , Feminino , Sobrevivência de Enxerto , Humanos , Masculino , Pessoa de Meia-Idade , Rinoplastia/métodos , Costelas , Estatísticas não Paramétricas , Adulto Jovem
18.
Diagn Interv Radiol ; 16(2): 129-31, 2010 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-19821257

RESUMO

Paranasal schwannomas are uncommon lesions, representing less than 4% of all head and neck schwannomas. They give rise to nonspecific symptoms such as nasal obstruction, epistaxis, and anosmia. Imaging features are generally nonspecific. Here, we present the radiologic features of a benign schwannoma of the middle turbinate with dural invasion in a 71-year-old woman.


Assuntos
Neurilemoma/diagnóstico por imagem , Neoplasias Nasais/diagnóstico por imagem , Neoplasias dos Seios Paranasais/diagnóstico por imagem , Conchas Nasais/diagnóstico por imagem , Idoso , Biópsia , Diplopia/diagnóstico por imagem , Diplopia/etiologia , Dura-Máter/diagnóstico por imagem , Dura-Máter/cirurgia , Epistaxe/diagnóstico por imagem , Epistaxe/etiologia , Feminino , Humanos , Neurilemoma/patologia , Neurilemoma/cirurgia , Neoplasias Nasais/patologia , Neoplasias Nasais/cirurgia , Neoplasias dos Seios Paranasais/patologia , Neoplasias dos Seios Paranasais/cirurgia , Tomografia Computadorizada por Raios X/métodos , Conchas Nasais/patologia
19.
Plast Reconstr Surg ; 123(6): 1704-1709, 2009 06.
Artigo em Inglês | MEDLINE | ID: mdl-19342991

RESUMO

BACKGROUND: Various surgical treatment modalities are available for inferior turbinate (IT) hypertrophy. Each is related with well-established complications, but still there is a lack of consensus on the optimal technique. Outfracture of the IT is thought to be a minimal destructive procedure among all other reductive turbinate interventions. Our aim was to assess the long term effects of IT outfracture technique in patients with mild or moderate IT hypertrophies. METHODS: Twenty ITs in 10 patients were outfractured during a septoplasty procedure. The distance of the IT bone to the lateral nasal wall was compared at 3 different levels of the nasal passage before and after (at 9 months) surgery with computed tomography scans of each patient at (1) the first section in which the IT bone could be seen entirely (anterior portion), (2) the level of the maxillary sinus ostium (middle portion), (3) the last section in which the IT bone could be seen entirely (posterior portion). RESULTS: A statistically significant degree of lateralization was observed at all levels in all patients. The mean lateralization rates were 15%, 26%, and 23% for the right side, and 26%, 29%, and 25% for the left side at first, second, and third levels, respectively. There was no bleeding, edema, or crusting due to the outfracture procedure in any patient. CONCLUSIONS: Our results suggest that outfracture of the IT is an effective and durable technique, which can be performed easily to enlarge the nasal airway in mild and moderate IT hypertrophies with minimal morbidity.

20.
Eur Arch Otorhinolaryngol ; 266(9): 1365-71, 2009 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-19242710

RESUMO

There exists no functional guide that can serve as a diagnostic tool for individual susceptibility to motion sickness (MS). We evaluated vestibular system functioning via a caloric test (which assesses functioning of the superior vestibular nerve) and the vestibular-evoked myogenic potentials (VEMP) test (which assesses inferior vestibular nerve functioning) in 20 MS susceptible and 20 nonsusceptible individuals. Susceptibility to MS was determined by self-declaration and with MS susceptibility questionnaire and Hamilton Anxiety Scale (HAS). We found statistically significant differences for scores on the MS susceptibility questionnaire and HAS questionnaire; however, we found no correlation between VEMP and caloric test results. We suggest that VEMP and caloric test results are not affected by individuals' susceptibility to MS. We could not find vestibular system deficits using the VEMP and caloric test combination. Our findings do not support vestibular function asymmetry in MS patients.


Assuntos
Enjoo devido ao Movimento/fisiopatologia , Testes de Função Vestibular , Adulto , Suscetibilidade a Doenças , Eletromiografia , Potenciais Evocados , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Nervo Vestibular/fisiopatologia , Vestíbulo do Labirinto/fisiopatologia
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