[Effect of ionizing radiation on functional activity of macrophagesi]. / Vliianie ioniziruiushchei radiatsii na funktsional'nuiu aktivnost' makrofagov.

It was shown that in vitro irradiation (8 Gy) of murine peritoneal macrophages suppressed their spontaneous cytotoxity and induced growth-stimulating activity. Exposure to 4 Gy induced mRNA proximal factors--TGF-beta and TNF-alpha and boosted growth-stimulating activity. These effects should be considered when evaluating efficacy of radiotherapy for tumors.